Objective: To investigate the effect of oat on blood glucose、insulin and serum lipid in aged patients with type-2 diabetes mellitus.Methods: Blood glucose(FBG,PBG),insulin(F-INS,P-INS) and serum lipid(TG,TC) were determined in eighty aged patients with type-2 diabetes mellitus before and after 50-100 g oat intake. Results: FBG,PBG and P-INS were decreased significantly(P

Objective To investigate the extracellular and intracellular free amino acid concentrations in healthy subjects and its changes in chronic renal failure(Car) .Methods The free amino acid concentrations in the plasma, in the erythrocytes and in the skeletal muscle of 15 patients with CRF were compared with those in ten healthy subjects.Results In healthy subjects, there was little ~difference between the concentrations in erythrocytes and in plasma for most amino acids; but in ~erythrocytes the concentrations of Asp, Glu, Ser were higher than those in plasma (P

Bone Neoplasms ; pathology ; Female ; Giant Cell Tumors ; pathology ; Humans ; Middle Aged ; Petrous Bone ; pathology

Animals ; Drugs, Chinese Herbal ; chemistry ; Humans ; Medicine, Chinese Traditional ; Microscopy, Confocal ; Muscle, Smooth, Vascular ; ultrastructure

Adolescent ; Adult ; Diabetes Mellitus, Type 1 ; blood ; complications ; genetics ; Diabetic Angiopathies ; blood ; complications ; Female ; Gene Frequency ; Genotype ; Homocysteine ; blood ; Humans ; Male ; Methylenetetrahydrofolate Reductase (NADPH2) ; genetics ; Mutation ; Polymorphism, Genetic ; Regression Analysis

Objective To investigate the prognosis of isolated fetal pyelectasis detected by ultrasound.Methods A total of 109 cases of isolated fetal pyelectasis (renal pelvis anteroposterior diameter ≥ 5 mm by ultrasound screening at any gestational age without structural or chromosome abnormalities) detected by prenatal ultrasound screening from March 2004 to July 2014 in Obstetrics & Gynecology Hospital of Fudan University,were delivered and followed up until neonatal period on chromosome examination,prenatal B ultrasound and outcome of neonates.Receiver operating characteristics curves were plotted and used to predict the optimal critical point of poor prognosis and the warning point of follow-up.Results Among the 109 cases,83 cases tended to have a natural recovery during pregnancy,71 of them had normal renal pelvis.Two of the neonates died,9 cases needed surgical treatment,and 98 cases had normal renal pelvis or need follow-up only.The area under the receiver operating characteristics curves was 0.860 (95％CI:0.860± 1.96 × 0.112).The optimal critical point of poor prognosis was determined at ≥ 11 mm in anteroposterior diameter with sensitivity 81.8％,and specificity 83.7％,and the warning point of prenatal follow-up was at ≥ 7 mm in anteroposterior diameter with sensitivity 100.0％ and specificity 50.0％.Conclusions The prognosis of isolated fetal pyelectasis is mostly good.The fetus with pyelectasis thicker than 7 mm should be followed-up closely during prenatal and neonatal period,and the fetus with pyelectasis thicker than 11 mm is likely to have poor prognosis in neonatal period.

This article discusses the ethical problems about Senile patients of dermatosis and venereal disease in the diagnosis and treatment.The problems mainly include:(1)moral responsibility is not strong and skills are not taken into account when inquiring history;(2)it is not careful enough and personality of patients may be hurt when making medical examination;(3)attitude is not solemn and operation not normative;(4)treatment is not normative and charcteristics of senile patients are not considered.We bring forward some suggestions including of:(1)moral responsibility must be strong enough and skills should be taken into account when inquiring history;(2)it must be careful engough and personality of patients may be respected when making medical examination;(3)attitude must be solemn and operation must be normative;(4)characteristics of senile patients must be considered and treatment should be reasonable;(5)life of senile patients should be respected and cherished,the quality of life should be attached importance to:

Objective To study the dose distribution of intra-cavitary NiTi metal-stent for correction in radiotherapy of esophageal carcinoma.Methods Thermoluminescence Dosimeter(TLD) with LiF dose units was used to simulate the dose variation in wax phantom with or without Chinese and Japanese metal stents in esophageal lumen on 60Co, 4 MV X-ray and 6 MV X-ray machines. The dose distribution on the stent fringe (i.e.,on the esophageal mucosa) was compared with that at the center of esophagus without metal stent.Results When a single anterior field was used to irradiate the esophageal carcinoma, the dose enhancement on the anterior and posterior point of the Chinese metal stent was 16.2% and 7.8% by 60Co,15.4% and 6.8% by 4 MV X-ray and 12.8% and 5.8% by 6 MV X-ray. With the same set-up, the dose enhancement of Japanese stent was 13.0% by 6 MV X-ray. When anterioposterior and posterioanterior (AP/PA) opposing fields were used ,the dose enhancement ratio was 11.7%～24.0%. When three fields from three different directions were used ,the dose were increased by 3.2～16.2%.Conclusions When irradiating esophageal carcinoma with intra-cavitary metal stent,we suggest the fraction dose be below 1.7 Gy when one field is used and not exceed 1.5 Gy when AP/PA fields are used. It is advisable to use the three field technique with the diameter of the stent limited to 1.5 cm.

Objective To investigate the role of connective tissue growth factor (CTGF) in transdifferentiation of human renal tubular epithelial cells (HKC).Methods Cultured HKC were divided into 3 groups: (1) negative control; (2) low dose CTGF treated (rhCTGF 2. 5 ng/ml); (3) high dose CTGF treated (rhCTGF,5. 0 ng/ml). Expression of ?-smooth muscle actin (?-SMA) and fibronectin(FN) mRNA were measured by RT-PCR. Indirect immunofluorescence and flow cytometry methods were used to assess the level of intracellular ?-SMA protein. Concentration of FN secreted into the media was determined by ELBA. Results Upon the stimulations of different concentrations of rhCTGF,expression of ?-SMA and FN mRNA increased markedly(P

This article discusses the ethical problems about Senile patients of dermatosis and venereal disease in the diagnosis and treatment.The problems mainly include:(1)moral responsibility is not strong and skills are not taken into account when inquiring history;(2)it is not careful enough and personality of patients may be hurt when making medical examination;(3)attitude is not solemn and operation not normative;(4)treatment is not normative and charcteristics of senile patients are not considered.We bring forward some suggestions including of:(1)moral responsibility must be strong enough and skills should be taken into account when inquiring history;(2)it must be careful engough and personality of patients may be respected when making medical examination;(3)attitude must be solemn and operation must be normative;(4)characteristics of senile patients must be considered and treatment should be reasonable;(5)life of senile patients should be respected and cherished,the quality of life should be attached importance to: