China ; Congresses as Topic ; Humans ; Integrative Medicine ; methods ; trends ; Medicine, Chinese Traditional ; methods ; trends ; Societies, Medical ; organization & administration

The prevalence of obesity,type 2 diabetes,and other chronic non-communicable diseases is increasing rapidly world-wide.Most recent epidemiological data showed that China is now in an era of obesity,and under a huge burden of the complications related with obesity,diabetes,as well as cerebral-and cardiovascular disorders.Strenuous efforts,comprehensive strategies,effective measures,and practical solutions must all be taken to combat against these chronic diseases.

The cardiovascular system is closely associated with sex hormones. The risk factors of the cadiovascular diseases or related events, such as lipid metabolism, coagulatory function and vascular endothelium function are affected by sex hormones and their analogues by a number of pathways. Consensus is generaly reached about hormone replacement therapy (HRT) among menopausal women except the effects on cardiovascular system, which removined to be controversial. It is recommended that women should consult their doctors for their individulized administration of HRT.

As the introduction of novel agents,the median overall survival of elderly newly diagnosed multiple myeloma patients has increased roughly from 30 to 60 months.But patients with high risk prognostic features still have a poor clinical outcome.This paper which combined the 19th annual congress of the European Hematology Association (EHA) reviews the advances in elderly patients with newly diagnosed multiple myeloma,including standard of care,the way to treatment and prognostic factors.

Objective: To observe the anti-hypertensive effect of pomegranate polyphenols in spontaneously hypertensive rats ( SHR) and explore the underlying mechanism. Methods:Totally 40 male SHR rats at the age of 12 weeks were randomly divided into five groups:SHR control group, pomegranate polyphenols groups respectively at the dose of 120 mg·kg-1 , 240 mg·kg-1 and 480 mg ·kg-1 , and captopril group at the dose of 15 mg·kg-1 . The age-matched Wistar-Kyoto ( WKY) rats were randomly divided into two groups:WKY control group and pomegranate polyphenols group at the dose of 480 mg·kg-1 . All the rats were given corresponding drug or water by intragastric administration for four weeks. The systolic blood pressure ( SBP) and diastolic blood pressure ( DBP) were measured weekly. After the 4-week administration, the rats were fasted 12 hours and anaesthetized with 25% urethane solution. The blood samples were collected from abdominal aorta. The serum concentrations of angiotensin II ( Ang II) and endothelin ( ET) were de-termined by euzymelinked immunosorbent assay. The concentration of nitric oxide ( NO) in serum was determined by nitrate reduction test. Results:Pomegranate polyphenols could significantly lower the SBP and DBP, decrease the serum concentrations of Ang II and ET, and increase the serum concentration of NO(P<0.05 or P<0.01). In addition, pomegranate polyphenols had no effects on blood pressure and vasoactive substances in WKY rats. Conclusion: Pomegranate polyphenols has anti-hypertensive effect in SHR rats. The mechanism may be related to regulating the expression of vasoactive substances, such as Ang II, ET and NO.

Objective To probe into the relationship of self-management behavior and hope level in patients with coronary heart disease after percutaneous coronary intervention (PCI).Methods The research instruments included three questionnaires:the Coronary Artery Disease Self-management Scale,the Herth Hope Scale and the demographic characteristics of respondents.Results Self-management behavior was in medium level and it was necessary to be improved.The total score of self-management behavior was positively correlated with hope level.Conclusions Medical workers should fully understand the status of selfmanagement behavior,and promote desirable self-management behavior through increase of hope level.

Since the 1960s,endovascular coil embolization has gradually become another treatment for intracranial aneurysms in addition to craniotomy clipping surgery,and in recent years,it has become the preferred method for many neurologists.However,the complexity of intracranial vascular anatomy and the diversity of intracranial aneurysm make the coil embolization alone unable to meet the needs of all intracranial aneurysms.And then some novel materials and techniques emerged,such as coated coils,balloon-assisted embolization,stent-assisted embolization,and covered stents.The principle of covered stents for the treatment of intracranial aneurysms is to place a kind of stents with bio-physical barriers into the parent arteries,while maintaining the patency of the parent artery,thus isolating aneurysms,leading to thrombogenesis inside and finally curing the lesions while maintaining the patency of parent arteries.It has huge advantage in the treatment of wide-necked,huge,dissecting and pseudo aneurysms without important adjacent branch vessels.This article reviews the application situation and the prospects of development of covered stents in the treatment of intracranial aneurysms.

BACKGROUND:Rabbit VX2 hepatocarcinoma models are characterized by expanded and infiltrative growth, abundant blood supply, similar pathological and imaging features to human hepatocelular carcinoma, so this model is ideal for imaging experiments. OBJECTIVE: To establish rabbit VX2 hepatocarcinoma models and compare two different laparotomy methods in establishing rabbit VX2 hepatocarcinoma models. METHODS:Thirty New Zealand rabbits were randomly divided into two groups: traditional laparotomy (tumor particles were directly embedded into the liver with tweezers) and improved laparotomy (tumor particles were injected into the liver through a 15G syringe needle). The growth features of the tumor established in two different ways were compared by ultrasound. RESULTS AND CONCLUSION:The tumor formation rate was 100% in the two groups; the single rate was respectively 50% and 90%; the ectopic implantation rate was 50% and 10%, there were significant differences between two groups (P < 0.05). The mortality rate within 2 weeks was 33% and 0 in the two groups, with significant differences (P < 0.05). The improved laparotomy method is feasible for modeling rabbit VX2 hepatocarcinoma, due to minimal injury, short operation time, high success rate and stable features.

NKG2D is an activating receptor expressed on various immune cells' surfaces.Currently,eight ligands have been found,they can be divided into two kinds:MHC Ⅰ related protein and ULBP molecules.NKG2D receptors and their respective ligands differentially exist in normal and cancerous tissues.So far,many researchers have found that a lot of immune cells' anti-tumor mechanism is mediated by NKG2D receptor and it can't be replaced in the resistance to the development of carcinoma.adoptive immunotherapy is a new method of treating cancer that propose to find tumor-specific cytotoxicity immune cells and enlarge the amount of it,then injected into human body to resist tumor.Recently,many researchers have found that DNT cells (CD4-CD8-T 细胞)have the function of anti-tumor;sadly its mechanisms are unclear.After the summary of NKG2D receptor-mediated pathway of destruction,this paper try to analyze its relevance to DNT cells' killing effect,on the purpose of finding the Killing mechanism of DNT cells that may existed.

According to the texts of Baihu Jia Renshen Decoction in the books of Maijing,Qianjin Yaofang,Qianjin Yifang,Taiping Shenghui Fang,Hxin Fang,and Jingui Yuhan Jing,the author drew the following conclusions:Baihu Jia Renshen Decoction in the present Shanghan Lun was very likely the written error Of Baihu Decoction,which was more close to the original meaning of Zhang Zhong-jing.From the period of Sui and Tang Dynasty,doctors had gotten new experiences in their practices.They added Ginsen into Baihu Decoction and named the new decoction"BaihU Jia Renshen Decoction",which was still in use today.Although there was not intrinsically difierence between Baihu Decoction and Baihu Jia Renshen Decoction,while the saying of"adding Renshen or not,should be decided by patient's Yuanqi"by doctor Shu Chi-yuan in Qing Dynasty had a significant impact.The erroneous views by some recent scholars can't be complied with,who advocated that the four main symptoms of Baihu Decoction syndrome should belong to syndrome of Baihu Jia Renshen Decoction according to the original texts in Shanghan Lun.