2.The prevention and treatment of chronic diseases: an important heavy task with an uneasy long haul
Chinese Journal of Endocrinology and Metabolism 2015;31(10):837-838
The prevalence of obesity,type 2 diabetes,and other chronic non-communicable diseases is increasing rapidly world-wide.Most recent epidemiological data showed that China is now in an era of obesity,and under a huge burden of the complications related with obesity,diabetes,as well as cerebral-and cardiovascular disorders.Strenuous efforts,comprehensive strategies,effective measures,and practical solutions must all be taken to combat against these chronic diseases.
3.Clinical value of OCT in the diagnosis of patients with normal tension glaucoma
Zhonghai CHEN ; Changchang ZHU
Chinese Journal of Primary Medicine and Pharmacy 2016;23(9):1417-1419
Objective To analyze the application value of optical coherence tomography (OCT)in the diagnosis of normal tension glaucoma (NTG).Methods 50 NTG patients (92 eyes)were selected as control group, at the same period 50 cases in our hospital physical examination center for the health examination were selected as the observation group.The optic disc and retinal nerve fiber layer thickness were measured by OCT.The disc diameter, disc area,depending on the cup diameter,optic cup area in the optic disc parameters were observed and compared between the two groups.Results The optic disc diameter between the control group and the observation group had no significant difference (t =1.02,P >0.05),the differences among the remaining nine parameters were significant (t =3.11,2.85,5.63,5.21,4.13,3.06,3.10,6.58,4.36,all P <0.05).Conclusion OCT can measure and analyze the optic disc and retinal nerve fiber layer quantitatively,it is reproducible,clinical early diagnosis of NTG is of great significance,it is worth popularization and application.
4.Analysis of correlation between NKG2D receptor pathway and the mechanism of DNT cell' killing effect
International Journal of Surgery 2015;42(6):429-432
NKG2D is an activating receptor expressed on various immune cells' surfaces.Currently,eight ligands have been found,they can be divided into two kinds:MHC Ⅰ related protein and ULBP molecules.NKG2D receptors and their respective ligands differentially exist in normal and cancerous tissues.So far,many researchers have found that a lot of immune cells' anti-tumor mechanism is mediated by NKG2D receptor and it can't be replaced in the resistance to the development of carcinoma.adoptive immunotherapy is a new method of treating cancer that propose to find tumor-specific cytotoxicity immune cells and enlarge the amount of it,then injected into human body to resist tumor.Recently,many researchers have found that DNT cells (CD4-CD8-T 细胞)have the function of anti-tumor;sadly its mechanisms are unclear.After the summary of NKG2D receptor-mediated pathway of destruction,this paper try to analyze its relevance to DNT cells' killing effect,on the purpose of finding the Killing mechanism of DNT cells that may existed.
5.Determination of Trace Resorcin in Waste Water by Kinetic Spectrophotometry
Journal of Environment and Health 1993;0(01):-
Objective To establish a new spectrophotometry for determination of trace resorcin. Methods Resorcin can inhibit discolouring reaction of bromophenol red induced by H2O2 ,which is catalyzed by Fe(Ⅲ) in NH3-NH4Cl medium. Results The detection limit of this method was 0.054 ?g/ml, linear range was 0.16-2.6 ?g/ml, the optimum reaction temperature was 75℃ and the optimum reaction time was 4 min. Conclusion The present method is simple, accurate and can be used to determine trace resorcin in waste water.
6.Setting up and Running of Automatic Outpatient Pharmacy
China Pharmacy 2007;0(31):-
OBJECTIVE: To provide references for the setting up and running of automatic management in pharmacy. METHODS: The application of ROWA automated storage system after the setting up of automatic outpatient pharmacy in our hospital and its impact on the outpatient pharmacy were analyzed. RESULTS & CONCLUSIONS: The ROWA automated storage system has helped improve the working environment and efficiency of service, reduce labor intensity, increase the connotation of services, and the competitiveness, promote hospital's service brand as well as creating better social and economi- cal benefits.
7.Analysis of diagnosis and treatment of intrahepatic biliary cystadenoma
Chinese Journal of General Surgery 2001;0(08):-
Objective To improve the recognition of intrahepatic biliary cystadenoma.Methods The clinical manifestations,radiologic features,diagnosis and surgical treatment of 18 patients with intrahepatic biliary cystadenomaadmitted in our hospital during the recent 8 years were retrospectively analyzed.Results Four cases were discovered by general medical examination,while the other 14 patients had varying symptoms that included right upper abdominal discomfort or pain in 11 cases,abdominal mass in 3 cases,and jaundice accompaniedby fever in 2 cases.B ultrasound and CT scan showed intrahepatic cystic occupying lesions consistingof multilocular or single cyst,and usually with papillary structures in the cyst wall.All of 18 cases received surgical resection.The patholgic dingnosis was intrahepatic biliary cystadenoma in all the 18 cases,and 6 of them showed malignant change.The average survival time of maligmant patients was 35(27-58)months.Conclusions Preoperative diagnosis of intrahepatic biliary cystadenoma is difficult.Intrahepatic biliarycystadenoma is easy to develop into cystadenocarcinoma.Early surgical resection is necessary,and can effectively prevent recurrence or malignant transformation.
8.Effects of Nimodipine on Peripheral Facial Paralysis and Hearing in Mimetic Convulsion Patients after Mi-crovascular Decompression
China Pharmacy 2016;27(5):681-683
OBJECTIVE:To observe the effects of nimodipine on peripheral facial paralysis and hearing in mimetic convulsion patients after microvascular decompression. METHODS:162 mimetic convulsion patients underwent microvascular decompression were enrolled in this study,and then randomly divided into control group and observation group,81 cases in each group. Control group was given routine microvascular decompression,and observation group was additionally given intravenous pump of Nimodip-ine injection 40 mg,qd,2 mg/h for consecutive 3 days after operation,and then given Nimodipine tablet 40 mg,qd,for 10 days. The incidence of peripheral facial paralysis and hearing disorder,onset time,duration time and severity of facial paralysis were ob-served in 2 groups. RESULTS:The incidence of peripheral facial paralysis and hearing disorder were 8.6% and 6.2% in observa-tion group,which were significantly lower than 14.8%and 11.1%of control group,with statistical significance(P<0.05). The on-set and duration time of peripheral facial paralysis was(15.32±3.15)d and(36.52±5.84)d in observation group,which were sig-nificantly later and lower than(12.21±2.16)d and(44.73±6.57)d of control group,with statistical significance(P<0.05). Ac-cording to House-Brackman classification method,the incidence of Ⅲ、Ⅳ facial paralysis was lower in control group than that in observation group,with statistical significance (P<0.05). CONCLUSIONS:Nimodipine can significantly decrease the incidence of peripheral facial paralysis and hearing disorder in mimetic convulsion patients after microvascular decompression,and contrib-utes to the recovery of injured nerve function.
9.The change and significance of local plasma fibrinogen during acute myocardial ischemia
Chinese Journal of Pathophysiology 1986;0(02):-
It is general belied that myocardial ischemia caused an increase of plasma fibrinogen(Fg),but the changes of Fg in ischemic region is not clear.In 17 open chest dogs, an external stenosis or infarction was produced by a micro-meter constrictor on left circumflex coronary artery. The changes of Fg and platelet count(PC) in coronary sinus were observed for 60 min. The results showed that acute myocardial ischemia produed a decrease in Fg when coronary artery stenosis was more than 75%; there was also a decrease in PC when stenosis was more than 90%. The reduced amplitude of PC was more than that of Fg. Histopathologic examination confirmed the presence of damanged endothelial cell, platelet adhesion and aggregation coronary thrombosis and microemboli in ischemic region It is suggested that acute myocardial ischemia lead to a decrease of Fg in the ischemic myocardium, which was associated with platelet aggregation and coronary thrombosis.
10.Human peripheral blood lymphocytes causing destruction of sheep erythrocytes
Chinese Journal of Pathophysiology 1986;0(01):-
Human peripheral blood lymphocytes and sheep red blood cells(SRBC)were incubated together in Hanks solution containing Ca~(2+) and Mg~(2+) ion, causing SRBC destruction and release of hemoglobin, 500%hemolysis value was found to 6.1921?0.06. The destruction of SRBC by lymphocytes was inhibited by trypsinase, its 50% hemolysis value became 0.0348?0.03 (P