Cerebral Palsy ; physiopathology ; rehabilitation ; Child ; Disability Evaluation ; Humans ; Motor Skills ; Movement ; Muscle Spasticity ; physiopathology ; rehabilitation ; Neuropsychological Tests

Cancer cachexia is a state of highly wasting in the terminal stages of cancer, which is characterized by the depletion of adipose tissue, muscle wasting and body weight loss.Loss of fat depots is more prominent than muscle wasting and often precedes.The enhancement of lipolysis, free fatty acids oxidation and white adipose tissue browning, the reduction of lipogenesis, lipid deposition and adipogenesisare important factors causing fat loss.Tumor necrosis factor α, interleukin-6 and zinc α2-glycoprotein are mediators involved in the process of depletion of adipose tissue, thus the drugs targetingthese mediators show a good promise for the treatment of cancer cachexia.The attention paid to the mechanism of depletion of adipose tissue contributes to the development of new therapeutic methods and drugs.

Objective:To evaluate the present situation and trend of antifungal medicines used in 34 hospitals in Wuhan area. Methods:The sales volume,market share,DDDs and DDC of antifungal medicines in 34 hospitals in Wuhan area during 2012 and 2014 were statistically analyzed. Results:The consumption sum and growth rate of the medicines were increased year by year, and those of pyrrolic medicines were the highest. The sales volume of voriconazole ranked the first. The DDDs of clotrimazole vaginal tablets and nifuratel-nysfungin suppositories ranked the top two. Conclusion:The consumption of antifungal medicines in Wuhan area has been increased greatly and the consumption structure is relatively stable. The utilization evaluation of antifungal medicines should be enhanced. Antifungal medicines should be rationally used to prevent or slow down the spread of drug resistant bacteria.

Hematopoietic stem cell transplantation (HSCT) has been widely performed for patients with various genetic and acquired malignant and non-malignant diseases.Central nervous system (CNS) complications are considered an important cause of morbidity and mortality after HSCT.This review discuss the main causes of CNS after HSCT such as infection,drug toxicity,graft-versus-host disease,metabolic encephalopathy,neurologic relapses etc,so as to benefit the early recognition of CNS complications and to improve the prognosis of patients after HSCT.

Objective We aimed to assess the influence of space teaching on junior-college nursing students' autonomous learning ability.Methods Using random number table,two classes of junior-college nursing students of Grade 2012 were selected and divided into the experimental group (46 students) and the control group (47 students) according to their classes.Students in the control group received routine multimedia teaching.Students in the experimental group received space teaching based on the platform of World University City.The effect of space teaching on developing nursing students' autonomous learning ability was assessed with the help of their test results and the nursing students' autonomous learning ability evaluation form.Results After carrying out space teaching,the average grade,theoretical performance,total points,the total score of autonomous learning ability and the score of each dimension in the experimental group and the differences were remarkably higher than those of the control group (t value was 2.80,2.45,2.29 and 11.58).Conclusions Space teaching can assist in arousing nursing students' learning motivation and improving nursing students' independent learning ability.It can be used for reference and promoted.

OBJECTIVE:To evaluate the permeation enhancing effect of Flos Caryophylli volatile oil versus azone on diclofenac sodium.METHODS:Percutaneous absorption experiment was performed on the apparatus of isolated skin,and the penetrated amounts of diclofenac sodium at different time were measured,then the steady-state flux and enhancing rate were calculated,and the deposit effect of diclofenac sodium was investigated.RESULTS:Flos Caryophylli volatile oil and azone all had promotion effect on percutaneous absorption of diclofenac sodium,especially when they used in combination.Used either in combination or alone,they all had remarkable enhancement property on deposit effect of diclofenac sodium(P

Objective To understand the natural lighting in houses in constructed in different times island city and the influential factors in Dinghai, Zhoushan. Methods 3 districts, 92 families living in the buildings with 4-6 floors were chosen in Dinghai, Zhoushan, the daylight factor and the ratio of the window and the floor were determined, the subjective evaluation such as good, common, worse, the worst was done among 323 person according to the Code of Housing Design,GB50096-1999, Daylight Code of Building Design, GB50033-2001, Design Code for Planning City Residential Areas, GB50180-1993. Results The daylight in all the investigated houses met the requirement in GB50180-1993. The ratio of the window and the floor in the living room, bedroom, kitchen was larger than 1/7, that of the dinning room was more than 1/10, which met the requirement in GB50096-1999, in addition, the ratio of the newly buildings was higher than that of the old. The total qualified rate of the lowest daylight factor was 58.2, the main bedroom ranked the best, the living room ranked the worst, significant different results were seen in the houses constructed in different times, in 1980s, 1990s and 2000, it was 43.3%, 54.7% and 76.7% respectively. 91.9 percent of people who living in the first floor think the natural lighting worse, even the worst. Conclusion All the natural lighting designs for the involved houses in the island city can meet the requirements in the national standard of China, some people still complained the bad natural lighting, especially those who living in the lower floors.

Stereotactic body radiotherapy (SBRT) is a treatment of high dose radiation in a single or small number fractions to the target areas.Compared with conventional radiotherapy,SBRT has the features of higher dose and better precision.The application in lung cancer can be summarized as the following three points:① SBRT has established the status of standard treatment for early (T1-2 N0 M0) nonsmall cell lung cancer (NSCLC) patients who unable or unwilling to undergo surgery.② The resuhs of preliminary application of SBRT in the operable NSCLC are not inferior to surgery.③ As for isolated metastases (1-3),the combination of systemic treatment and SBRT has been gradually accepted.This article makes a summary of this.

AIM:28 patients with congestive heart failure (CHF) were selected in this studyThe therapeutic scheme was as follows:after withdrawal of other vasodilators,urapidil was given in dose of 100～400?g/min intravenous drip;in severe case,the administration continued for 24～72 h;treatment lasted 3～6 daysThe patients'blood pressure,heart rate and LVEF were measured before and after treatmentRESULTS:The patients'clinical manifestations were markedly improved with a total effective rate of 89%LVEF was improved obviously too and the product of systolic pressure and heart rate was decreasedCONCLUSION:Urapidil is a vasodilator with slight side effects,reliable effectiveness and moderate action,and has undoubted therapeutic effect on CHF

OBJECTIVE:To discuss the development of the core competitive power of domestic vitamin C manufacturing enterprises.METHODS:To analyse the characteristic of vitamin C industry in China and the competitive situation in the new market enviroment after China entry into WTO and to study the value chain of Chinese enterprises.RESULTS&CONCLU?SION:In order to develop the new core competitive power,it is important to breed the core of value chain that is based on in?novation.