1.Relation of dietary fat with cardiovascular diseases
Journal of Medical and Pharmaceutical Information 2001;(11):10-15
The dietary fat and fatty acid influenced the process of arteriosclerosis and thrombosis. Current Vietnamese diet contains the low fat and protein, and high salt and carbohydrate. In order to prevent from arteriosclerosis and thrombosis, it should strengthen the fat in the diet concomitantly improve the quality of fat as trend of reduction of AI, TI index and n-6/n-3 ratio.
Dietary Fats
;
cardiovascular disease
2.Clinical characteristics, treatment and 2-year outcomes in Malaysian and Bruneian patients with stable coronary artery within the worldwide CLARIFY registry
Kok Han Chee ; Gim Hooi Choo ; Ahmad Nizar Jamaluddin ; Kauthaman Mahendran ; Nicola Greenlaw ; Chandran Krishnan
The Medical Journal of Malaysia 2017;72(5):282-285
Introduction: The on-going, international, prospective,
observational, longitudinal CLARIFY registry is investigating
the demographics, clinical profiles, management and
outcomes of patients with stable coronary artery disease
(CAD). This paper assesses baseline characteristics,
treatment, and clinical outcomes at two years’ follow-up of
Malaysian/Bruneian patients compared with the overall
registry population.
Method: Between November 2009 and July 2010, outpatients
from 45 countries who met the criteria for stable CAD were
recruited into the registry. Baseline characteristics were
documented at enrolment, and patients were reassessed
during their annual visits over a five-year follow-up period.
Key outcomes measured were sudden death and
cardiovascular (CV) death, non-CV death and CV morbidity.
Results: At baseline, 33,283 patients were available for
analysis within the registry; 380 and 27 were Malaysians and
Bruneians, respectively. The mean ages of
Malaysian/Bruneian patients and the rest of the world (RoW)
were 57.83 ±9.98 years and 64.23 ± 10.46 years, respectively
(p<0.001). The median body mass index values were 26.6
(24.4-29.6) kg/m2 and 27.3 (24.8-30.3) kg/m2
, respectively
(p=0.014). Malaysian/Bruneian patients had lower rates of
myocardial infarction (54.55% versus 59.76%, p=0.033) and
higher rates of diabetes (43.24% versus 28.99%, p<0.001)
and dyslipidaemia (90.42% versus 74.66%, p<0.001)
compared with the RoW. Measured clinical outcomes in
Malaysian and Bruneian patients at 2-years follow-up were
low and generally comparable to the RoW.
Conclusion: Malaysian/Bruneian patients with stable CAD
tend to be younger with poorer diabetic control compared
with the RoW. However, they had similar outcomes as the
main registry following two years of treatment.
Coronary Artery Disease
;
Cardiovascular Diseases
;
Heart Rate
3.Practicality and importance of selected endothelial dysfunction measurement techniques: review
Michael D WHITT ; Mark J JACKSON
Biomedical Engineering Letters 2019;9(1):87-95
The measurement of endothelial dysfunction (ED) has importance in that it indicates the presence of coronary artery disease (Kuvin et al. in J Am Coll Cardiol 38(7):1843–1849, 2001) in addition to acting as a predictor of future adverse events (Halcox et al. in Circulation 106:653–658, 2002). Various tools, methods, and metrics exist that can provide an indicator of endothelial dysfunction. Given the signifi cance of ED, it is of utmost importance to fi nd a measurement technique that is reliable, while defi ning a metric providing a framework for an overall system that is practical, accurate, and repeatable. Success would provide a tool for the early detection of cardiovascular disease not only moving patients that are currently classifi ed as asymptomatic to symptomatic, but also providing a method to monitor the effi cacy of treatments.
Cardiovascular Diseases
;
Coronary Artery Disease
;
Humans
;
Methods
4.Fetal origin of some chronic diseases associated with nutrition
Journal of Medical and Pharmaceutical Information 2003;0(6):6-8
The theory on establishment of programmed in the fetal period and chronic diseases haven’t still given out anything clearly but in most of studies, they showed that there is a relation between fetal growing with cardiovascular diseases, hypertension and metabolic syndrome. Its establishment of programmed in fetal period doesn’t replace other risk factors but adding more the environmental factor to these diseases. Currently, the important of fetal nutrition and mother nutrition in pregnancy period are paid attention as well as other nutrition issue in the transition period.
Nutrition Therapy
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Cardiovascular Diseases
;
Chronic Disease
;
Fetal Nutrition Disorders
7.Focused Update on Aspirin for Primary Stroke Prevention in Korean Clinical Practice Guidelines for Stroke.
Jaseong KOO ; Sang Won HAN ; Hahn Young KIM ; Jong Moo PARK ; Yong Jin CHO ; Kyusik KANG ; Kyung Ho YU ; Joung Ho RHA ; Ji Hoe HEO ; Sun Uck KWON ; Chang Wan OH ; Hee Joon BAE ; Byung Chul LEE ; Byung Woo YOON ; Keun Sik HONG
Journal of the Korean Neurological Association 2011;29(4):277-284
The first edition of the Korean clinical practice guidelines for primary stroke prevention reflects evidence published before June 2007. Since then, several clinical studies and meta-analyses have been conducted to determine the efficacy of aspirin for the primary prevention of cardiovascular disease including stroke. The aim of this guideline update is to provide timely recommendations taking into consideration the new evidence. Three clinical studies and four meta-analyses performed between July 2007 and November 2010 were identified and included for updating the guidelines. The main finding was a lack of aspirin efficacy for primary stroke prevention in patients with diabetes or peripheral arterial disease. We have summarized the new evidence and revised our recommendations for aspirin for primary stroke prevention. New evidence will need to be reflected continuously in future guideline updates.
Aspirin
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Cardiovascular Diseases
;
Humans
;
Peripheral Arterial Disease
;
Primary Prevention
;
Stroke
8.Serum leptin in non-alcoholic fatty liver disease: Ambiguous clinical implications concerning cardiovascular disease
Dimitrios PATOULIAS ; Konstantinos IMPRIALOS ; Konstantinos STAVROPOULOS ; Michael DOUMAS
Clinical and Molecular Hepatology 2019;25(3):331-332
No abstract available.
Cardiovascular Diseases
;
Leptin
;
Non-alcoholic Fatty Liver Disease
10.Association of metabolic dysfunction-associated fatty liver disease with coronary artery calcification among Filipino patients in a tertiary hospital in Cebu City
Mary Grace S. Nepomuceno ; Michael Albert M. Diy ; Aileen Mae L. Catapang
Philippine Journal of Internal Medicine 2025;63(1):39-44
BACKGROUND:
Non-alcoholic fatty liver disease (NAFLD), now known as Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD), is linked to cardiovascular disease. This renaming emphasizes the role of metabolic problems. Coronary artery calcification (CAC) reflects early coronary artery disease, but data on the MAFLD-CAC link is limited.
OBJECTIVE:
To demonstrate the association between metabolic dysfunction-associated fatty liver disease (MAFLD) based on its criteria and coronary artery calcification, as measured by CT CAC score.
METHODS:
This single-center retrospective study involved adult Filipino patients who underwent CT CAC scoring between January 2021 and January 2023. Clinical and laboratory data were obtained via review of electronic records.
RESULTS:
This study involved 147 patients with an average age of 62 years, primarily females (57.14%), and mostly falling into the Obese-Class I category (31.29%). The most common comorbidities were hypertension (95.24%), dyslipidemia (62.59%), and diabetes mellitus (38.1%). In terms of CAC scores using the CT Agatston method, majority (30.61%) had low calcium buildup (Stage 2 with scores between 1-99). Approximately 26.53% had higher liver fat content with liver HU below 40, while 73.47% had lower liver fat content with HU equal to or greater than 40. Furthermore, 25.17% of patients with fatty livers and other risk factors were diagnosed with MAFLD, while 74.83% were not. The p-value indicated a significant difference in proportions, suggesting a lower proportion of MAFLD among those who had undergone CT CAC scoring. However, the Pearson Chi-Square statistic (4.051) and the p-value (0.256) indicated no statistically significant association between MAFLD and CT CAC.
CONCLUSION
The study found a notably lower proportion of MAFLD diagnoses in patients who underwent CT CAC scoring. Additionally, there was no statistically significant link between MAFLD and CT CAC.
Cardiovascular Diseases
;
Coronary Artery Disease
;
Fatty Liver, Alcoholic