Objective To sonographically measure nuchal skin thickness(NT) and biparietal diameter/femur length (BPD/FL) for normal fetuses between 10 and 24 gestational weeks,screen abnormal cases then to culture fetal cells and chromosome analysis, diagnosis aneuploid chromosome deformed fetuses Methods Ultrosonic estimation of fetal gestation according to gestational sac or CRL or BPD/Fl and AC, measuring NT, BPD/Fl of 100 cases per gestational weeks, drawing normal curve of NT, making curve of 90 th and 10 th NT and BPD/Fl. Restropectively analysis 5 cases trisomy 21.Results The average of NT was 1 76mm between 10 and 13 gestational weeks. The average of NT was 3 52mm between14 and 24 gestational weeks. The value of 50th was 2 40～1 40 between14 and 24 gestational weeks.Conclusions If the value of NT is more than 90 percent of normal fetuses, and if BPD/FL ratio is morn than 90 percent of normal fetuses,the sensitivity of trisome 21 should increase.Combining factors as elderly and high risk parturition, the sensitivity of trisomy 21 is much more increasing.

Objective To compare the causes of poor effects after surgical treatment for severe cervical spondylotic myelopathy,and to analyze the clinical value of posterior surgery in the treatment of severe cervical spondylotic myelopathy.Methods From September 2013 to November 2016,ninety-two patients with severe cervical myelopathy in Shiyan Medical Hospital were selected as the research object,the patients were divided into the observation group and the control group,50 cases in each group,according to the different surgical methods,the control group received anterior cervical discectomy and interbody fusion and internal fixation treatment,the observation group was treated with cervical posterior decompression surgical treatment,the prognosis and the changes of cervical vertebra function in the two groups were recorded.Results There were statistically significant differences between the two groups in terms of operation time,intraoperative blood loss and postoperative hospital stay(t=5.392,7.114,4.552,P<0.05).The intervertebral height at 1 month after surgery in the observation group and the control group were(4.92 ± 1.51)mm and(4.26 ± 1.32)mm,significantly lower than those before the operation((3.72±0.42)mm,(3.78±0.93)mm)(t=10.495,6.114,P<0.05) .At 1 month after operation,the intervertebral height of the observation group was significantly higher than that of the control group(t=4.521,P<0.05).The excellent and good rate of JOA score of the observation group and control group at 1 month after operation were 97.6% and 84.0%,respectively,and the rate of the observation group was significantly higher than that of the control group(χ2=4.797,P<0.05).In the observation group and the control group,there were 1 case of throat pain after operation,and they were relieved after suitable treatment.Conclusion Compared with the anterior approach,the posterior treatment of severe cervical spondylotic myelopathy can reduce the trauma of patients,promote the recovery of intervertebral height and improve the function of the cervical spine,so as to achieve better results.