ObjectiveTo study the relation between white blood cell(WBC) count and left ventricular (LV) remodeling after emergency percutaneous coronary intervention (PCI) in patients with acute myocardial infarction (AMI).MethodsA total of 117 ST segment elevation AMI patients having underwent emergency PCI were enrolled.WBC count,cardiac troponin Ⅰ (cTnI),high-sensitivity C-reactive protein (hs-CRP) and N-terminal pro-B-type natriuretic peptide(NT-proBNP) were obtained at admission before PCI.According to the WBC count level,patients were divided into normal WBC group(WBC count ≤ 10 ×109/L,60 cases) and elevated WBC group(WBC count＞ 10 × 109/L,57 cases).Two-dimensional echocardiography was applied after PCI.The relation between WBC count and LV remodeling prognosis including LV ejection fraction(LVEF),LV end diastolic diameter(LVEDD) and LV aneurysm were compared after AMI.ResultsAdmission NT-proBNP,hs-CRP and cTnI peak in elevated WBC group were higher than those in normal WBC group [ (2408.83 ± 3173.39) pg/L vs.(713.11 ± 636.82) pg/L,(39.64 ± 59.51) mg/L vs.(11.23 ± 14.14) mg/L,(107.76 ± 107.71) pg/L vs.(62.23 ± 87.79) pg/L,P ＜0.05].Admission WBC count was positively correlated with LVEDD and negatively correlated with LVEF(P ＜0.01 ).Patients with LV aneurysm had higher WBC count than those without LV aneurysm[ ( 12.59 ± 5.22) × 109/L vs. (9.27 ± 2.60) × 109/L,P =0.001 ].Multivariate analyses showed that admission WBC count ≥ 10.5 × 109/L was an independent determinant of LV aneurysm(OR =22.5,95％ CI:2.69-187.83,P ＜ 0.01 ),and this cut-off value yielded sensitivity of 76.9％ and specificity of 69.7％ respectively.Conclusion Admission WBC count may be considered as a prognostic biological tag in the prediction of the development of LV remodeling after emergency PCI in patients with AMI.

Objective To explore the prevalence and relationship of urinary incontinence and depression among elderly female patients.Methods A total of 118 female patients older than 60 years old were interviewed face to face.The prevalence of urinary incontinence and depression were estimated using the International Consultation on Incontinence Questionnaire Urinary Incontinence Short Form-Chinese (ICIQ-SF-Chinese) and Geriatric Depression Scale-15 (GDS-15).Linear regression and Spearman correlation were used to identify the relationship between urinary incontinence and depression.Results Urinary incontinence was found in 27.1％ (32/118),and depression was in 39.0％ (46/118) of the survey population.Urinary incontinence with depression was found in 13.6％ (16/118) of the overall population.Urinary incontinence was positively correlated with depression,r=0.211,P＜0.05.The frequency of entertainment and urinary incontinence were significantly related to depression symptoms,P＜0.05.Conclusions Urinary incontinence appears to possess an additive effect on incidence of depression,which seriously affects both physical and mental health of patients.Clinicians should give patients health education and intervention measures at early stage.

Objective To understand the incidence of common geriatric syndromes in hospitalized patients,and analyze the relationship between different kinds of geriatric syndromes.Methods A crosssectional study was conducted by five well-trained investigators-300 patients were chosen from geriatric department and medical department within 3 top three hospitals in Chengdu.Results 300 copies of questionnaires were distributed in total,and 300 questionnaires were returned (response rate 100％).Among those,277 questionnaires were considered valid (valid response rate 92.3％).Among those elderly which were above 65 years old,having risk of falling accounted for 91.3％,feeling pain accounted for 79.1％,chronic constipation accounted for 59.2％,having risk of malnutrition accounted for 49.1％,malnutrition accounted for 28.2％,having risk of pressure ulcers accounted for 32.5％,incontinence accounted for 25.3％,and dysphagia accounted for 17％.The correlation among these syndromes was signifcant.Conclusions The overall incidence of geriatric syndromes in hospitalized patients is higher than that in the community.These syndromes are correlated with each other.One can be a risk factor of other geriatric syndromes and also could affect each other.

Objective:To explore the mechanism of interleukin-1?(IL-1?) induced AHR.Methods:The authors work out an original model of AHR induced by IL-1? administered intratracheally to guinea pigs,and investigate the effects of neurokinin released from intrinsic airway neurons on the development of this airway hyperresponsiveness,PC 20 values were significantly lower in animals given IL-1? than that in controls( P 0 05),showing complete inhibition of IL-1? induced AHR by capsaicin pretreatment.PC 20 values were significantly higher in animals with NK 1 receptor antagonist pretreatment than that in animals exposed to IL-1?( P

Objective To observe and study the effect of PDCA circulation nursing management mode on the axial symptoms, quality of life and satisfaction of patients undergoing cervical operation.Methods A total of 100 patients with cervical vertebrae surgery in our hospital were randomly divided into experimental group and control group, with 50 cases in each group.The control group was given conventional nursing, and the experimental group used PDCA cycle nursing management mode of nursing, axial symptoms, the quality of life and satisfaction at discharge and in one-year after were compared.Results The experimental group had lower axial symptoms rate than the control group at discharge(P<0.01), and it was higher in one year after discharge than the control group(P<0.01).The quality of life score and satisfaction of the experimental group were significantly higher than that of the control group(P<0.01).Conclusion PDCA cycle nursing management model can significantly reduce the symptoms of patients with cervical spinal surgery, improve the quality of life and satisfaction of patients, so it is worthy of clinical practice.

Objective To observe and study the effect of PDCA circulation nursing management mode on the axial symptoms, quality of life and satisfaction of patients undergoing cervical operation.Methods A total of 100 patients with cervical vertebrae surgery in our hospital were randomly divided into experimental group and control group, with 50 cases in each group.The control group was given conventional nursing, and the experimental group used PDCA cycle nursing management mode of nursing, axial symptoms, the quality of life and satisfaction at discharge and in one-year after were compared.Results The experimental group had lower axial symptoms rate than the control group at discharge(P<0.01), and it was higher in one year after discharge than the control group(P<0.01).The quality of life score and satisfaction of the experimental group were significantly higher than that of the control group(P<0.01).Conclusion PDCA cycle nursing management model can significantly reduce the symptoms of patients with cervical spinal surgery, improve the quality of life and satisfaction of patients, so it is worthy of clinical practice.

Objective To explore the effect of continuous quality improvement nursing on HAMA, HAMD score and pain in patients with cervical spine fracture.Methods A total of 120 cervical spine fracture patients in our hospital were randomly divided into control group (n=60) and experimental group(n=60).The patients of control group received routine nursing care interventions while the patients of experimental group received continuous quality improvement nursing intervention.The Hamilton Anxiety Scale (HAMA), Hamilton Depression Scale (HAMD) score, visual analogue scale and nursing quality score were compared between the two groups before and after the intervention.Results Compared with intervention before, the scores of HAMD and HAMA in the two groups were decreased after treatment (P<0.05).The scores of HAMD and HAMA in the experimental group were significantly lower (P<0.05).Compared with intervention before, the visual analogue scores of the two groups were decreased in different degrees after intervention, and was significantly lower in experimental group than that of the control group (P<0.05).The quality of nursing was significantly higher than that of the control group (P<0.05).Conclusion Compared with conventional care, continuous quality improvement in the treatment of patients with cervical fractures can not only effectively improve the patient''s pain, but also help to improve negative emotions, and improve the quality of care.So it''s worthy of clinical promotion.

Objective To explore the attitude and knowledge towards elderly among undergraduate nursing student , and to investigate the factors which influencing their willingness to work with elderly . Methods A total of 112 freshmen and junior nursing students were chosen by convenience method as sample in one university and surveyed by demographic questions , the Kogan′s Attitude toward Older People ( KAOP) and the Palmore′s Facts on Aging Quiz 1 ( FAQ 1).Results 85.7% of participates had not learned the aging knowledge systematically , and 75.0% presented interest in aged people while 65.2% showed willingness to work for elderly .All students showed a positive attitude towards elderly ( KAOP >102 ) , and the freshmen acquired (145.5 ±11.3) scores while junior students gained (132.9 ±11.9) scores (t=5.6,P<0.05). Meanwhile, freshmen obtained (12.0 ±2.3) scores for the knowledge of aging whilst junior students achieved (12.9 ±2.5) scores (t=-2.0,P<0.05).The age of students had positive correlation with the knowledge of aging, but negative correlation with attitude towards elderly (r =0.231, -0.374,respectively;P <0.05). Students who were more interested in elderly showed more willingness to work for elderly (r=0.314,P<0.01). Conclusions Undergraduate nursing students have a positive attitude towards elderly , and have shortage of aging knowledge , which implied that we should change the curriculum model to improve the right view and interest toward elderly , and cultivate more excellent geriatric nursing students .

Objective To explore the effect of continuous quality improvement nursing on HAMA, HAMD score and pain in patients with cervical spine fracture.Methods A total of 120 cervical spine fracture patients in our hospital were randomly divided into control group (n=60) and experimental group(n=60).The patients of control group received routine nursing care interventions while the patients of experimental group received continuous quality improvement nursing intervention.The Hamilton Anxiety Scale (HAMA), Hamilton Depression Scale (HAMD) score, visual analogue scale and nursing quality score were compared between the two groups before and after the intervention.Results Compared with intervention before, the scores of HAMD and HAMA in the two groups were decreased after treatment (P<0.05).The scores of HAMD and HAMA in the experimental group were significantly lower (P<0.05).Compared with intervention before, the visual analogue scores of the two groups were decreased in different degrees after intervention, and was significantly lower in experimental group than that of the control group (P<0.05).The quality of nursing was significantly higher than that of the control group (P<0.05).Conclusion Compared with conventional care, continuous quality improvement in the treatment of patients with cervical fractures can not only effectively improve the patient''s pain, but also help to improve negative emotions, and improve the quality of care.So it''s worthy of clinical promotion.

Objective To investigate the home-based rehabilitation of stroke patients in China, and to compare the curative effects under different factors, so as to discuss the strategies for home-based rehabilitation. Methods A total of 234 cases of stroke patients who has been discharged from the center of rehabilitation medicine of a Class Ⅲ Grade A hospital were selected by random cluster sampling method. Family rehabilitation status of patients and their caregivers was investigated by outpatient follow-up, home follow-up and telephone follow-up survey. In the survey, the general information questionnaire, the Barthel Index (BI), the Instrumental Activities of Daily Living (IADL), the Self-perceived Burden Scale (SPBS) and the Zarit Caregiver Burden Interview (ZBI) were applied. Results The results showed that the BI score was (61.77±22.83). The average score of IADL was (7.25±6.26). The SPB score was (29.26±7.07). 91.13% of the patients in the study group had a sense of burden. The ZBI score of the caregivers was (43.97±12.28), 59.40% of which had moderate or severe burden. The result of single factor analysis showed that the differences in the scores of BI, IADL, SPBS and ZBI of patients in different gender were statistically significant (P＜ 0.05). There were significant differences in BI and IADL scores among patients of different ages, main caregivers, family rehabilitation time and caregivers' gender (P＜ 0.05). The differences in the scores of IADL and SPBS of patients with different educational level were statistically significant (P＜0.05). The differences in BI and ZBI scores of patients with different disease types were statistically significant (P＜0.05). Conclusions The family rehabilitation of stroke patients is poor. Medical workers should pay attention to the rehabilitation of patients after discharge, especially to female stroke patients, caregivers and to strengthen the rehabilitation knowledge training for male caregivers. It is suggested that community rehabilitation, family doctor responsibility system and hospital-community-family Union should be vigorously developed so as to improve the family rehabilitation of stroke patients, reduce readmission rate, increase the utilization of social resources, and improve the health level of the whole people.