Objective To evaluate the application of microcirculation temperature regulator for patient receiving reversed digital artery island flap surgery comparing with conventional heat lamp. Methods 68 patients after reversed digital artery island flap surgery in department of foot and hand surgery were randomized to treatment group using microcirculation temperature regulator (n=34) and control group using heat lamp (n=34) by random number table. Flap survival, length of hospital stay and satisfaction were evaluated. Results 100.00%of 34 flaps survived in the treatment group, higher than 67.65%(23 flaps of 34) in the control group, statistical differences were observed between two groups (χ2=13.123,P<0.01). Average length of hospital stay in treatment group was (11.6 ± 5.9) days, shorter than (19.5 ± 8.1) days in control group (t=4.600,P<0.01). Patients satisfaction rate was 100.00% (34/34) in microcirculation temperature regulator application group, which was also higher compared to using heat lamp 76.47% (26/34) (χ2=12.851,P<0.01). Conclusions Application of microcirculation temperature regulator could increase flap survival, shorten length of hospital stay, and improve patients′satisfaction.

OBJECTIVE:To analysis the characteristics and regularity of the adverse drug reaction(ADR)occurred in our hospital. METHODS:307 ADR cases collected from 2004 to 2008 in our hospital were analyzed statistically in respect of patient’s age and sex,route of administration,categories of drugs,organs and systems involved in ADR and clinical manifestations,etc. RESULTS:Of total 307 ADR cases,more cases were woman;45.93% of cases were aged ≤18 a and 60 a. 80.13% of ADR cases were induced via intravenous administration. The incidence of ADR cases were mainly induced by antiinfective drugs,accounted for 48.53%. The most common manifestation of the ADR was lesion of skin and its appendants(27.97%),followed by injury of digestive system(16.10%). CONCLUSION:Great importance should be attached to rational use of anti-infective drugs and its management to reduce or avoid the occurrence of ADR and improve the quality of ADR reports.