OBJECTIVE:To develop an HPLC method for the determination of Tanshinone ⅡA in Lianchuang pills. METHODS:The chromatographic separation was performed on Agilent Zorbax SB-C18 (250mm?4.6mm,5?m) column with column temperature at 25℃. The mobile phased consisted of methanol-water (75∶25) at a flow rate of 1.0mL?min-1.The detection wavelength was set at 270nm.RESULTS:The linear range of Tanshinone ⅡA was 0.020 2～0.202 0?g(r=0.999 9).The average recovery was 99.79%(RSD=1.01%,n=6). CONCLUSION:The method is simple, rapid and accurate, and it could be used for the quality control of Lianchuang pills.

AIM: To establish the quality control standard for Compound Dingfengzhitong Capsule (Radix Notoginseng, Radix Saposhnikoviae, Radix Angelicae Dahuricae). METHODS: Radix Saposhnikoviae, Radix Angelicae Dahuricae in capsule were identified by TLC, and the content of ginsenoside R g1 was determined by HPLC. RESULTS: Radix Saposhnikoviae, Radix Angelicae Dahuricae could be identified by TLC. The Ginsenoside R g1 showed a good linear relationship at a range of 0.5286?g～26.43?g, r=0.9999(n=6) , the average recovery was 99.94%, and RSD was 1.34%( n =9). CONCLUSION: The method is accurate with the good reproducibility and can be used for the quality control of Compound Dingfengzhitong Capsules.

OBJECTIVE:To establish a method for the identification of four chemicals-Ephedrina Hydrochloridum,prednisone acetate,codeine phosphate and dexamethasone acetate in antiasthmatic and antitussive Chinese patent medicine.METHODS:With Kening capsule(an antitussive) as positive control,the chemicals which were illegally added into the antiasthmatic and antitussive Chinese patent medicine were determined by HPLC with octadecylsilane chemically bonded silica as loading agent.RESULTS:Under the same chromatographic condition,the four chemicals could all be detected.CONCLUSION:The method is simple,practical and specific,and it can be applied to detect the illegally added chemicals in antiasthmatic and antitussive Chinese patent medicine.