1.The follow-up of post-mastectomy patients: Should the ipsilateral side be assessed with both mammogram and ultrasound?
Radhika Sridharan ; Hartini Baherin ; Norlia Abdullah ; Suria-Hayati Mohd Pauzi ; Zulfiqar Mohd Annuar
The Medical Journal of Malaysia 2016;71(5):282-287
Aim: This study aimed to determine findings of axillary view
mammogram (MMG) and ultrasound (USG) of the ipsilateral
side in post-mastectomy patients and to document difficulty
level in performing the axillary view and patients’ pain level
during the procedure.
Methods: Post-mastectomy patients who had MMG and USG
on follow-up during an 18-months period were included. The
MMG and USG findings of 183 patients were reviewed and
histology results were recorded when available.
Radiographers’ difficulty and patients’ pain level during the
axillary view MMG were charted.
Results: On MMG, 172 cases were normal, eight cases were
benign (Category 2) and three cases indeterminate
(Category 3). On USG, 175 cases were normal, three cases
were benign (Category 2) and five cases indeterminate
(Category 3). Malignant lesions detected in two out of 183
patients (1%) were metastatic carcinoma in bilateral axillary
lymph nodes and leiomyosarcoma at the mastectomy site.
These two cases were Category 3 on USG with negative
MMG findings. In majority of cases (79%), the radiographer
had no difficulty performing the axillary view compared with
contralateral MMG. Majority of patients (80%) experienced
similar pain during axillary view compared to contralateral
MMG.
Conclusion: Follow-up imaging of post-mastectomy patients
should include (i) USG of the mastectomy site, both axillary
regions, and the contralateral breast, and (ii) MMG of the
contralateral side. Ipsilateral axillary view MMG is not
necessary.
2.Accuracy of ultrasound versus computed tomography urogram in detecting urinary tract calculi
Salinawati Bakin ; Erica Yee Hing ; Fam Xeng Inn ; Zulfiqar Mohd Annuar
The Medical Journal of Malaysia 2015;70(4):238-241
Aim: To determine the (i) sensitivity and specificity of
ultrasound (USG) in the detection of urinary tract calculi, (ii)
size of renal calculi detected on USG, and (iii) size of renal
calculi not seen on USG but detected on computed
tomography urogram (CTU).
Methods: A total of 201 patients’ USG and CTU were
compared retrospectively for the presence of calculi.
Sensitivity, specificity, accuracy, positive predictive value
and negative predictive value of USG were calculated with
CTU as the gold standard.
Results: From the 201 sets of data collected, 59 calculi were
detected on both USG and CTU. The sensitivity and
specificity of renal calculi detection on USG were 53% and
85% respectively. The mean size of the renal calculus
detected on USG was 7.6 mm ± 4.1 mm and the mean size of
the renal calculus not visualised on USG but detected on
CTU was 4 mm ± 2.4 mm. The sensitivity and specificity of
ureteric calculi detection on USG were 12% and 97%
respectively. The sensitivity and specificity of urinary
bladder calculi detection on USG were 20% and 100%
respectively.
Conclusion: This study showed that the accuracy of US in
detecting renal, ureteric and urinary bladder calculi were
67%, 80% and 98% respectively.
Calculi
;
Urinary Calculi
3.Contrast enhanced Voiding Urosonography (ce-VUS) as a radiation-free technique in the diagnosis of vesicoureteric reflux: Our early experience
Faizah Mohd Zaki ; Hamzaini Abdul Hamid ; Kanaheswari Yoganathan ; Dayang Anita Abdul Aziz ; Zulfiqar Muhamed Annuar
The Medical Journal of Malaysia 2015;70(5):269-272
Objective: Contrast-enhanced ultrasound has become
increasingly utilised as an alternative imaging modality for
the diagnosis of vesicoureteric reflux (VUR) in paediatric
patients. The study objective is to evaluate the efficacy of
contrast enhanced Voiding Urosonography (ce-VUS)
compared with fluoroscopic micturating
cystourethrography (MCU) in the detection of VUR.
Methods: This prospective study was carried out between
July 2011 and January 2013 on paediatric patients who
underwent MCU. All consented patients would undergo ceVUS
prior to MCU. We documented the epidemiology details,
the number of Kidney-Ureter (K-U) unit studied, baseline
renal and bladder sonogram, as well as presence of VUR on
ce-VUR. The technique for ce-VUS was standardized using
normal saline to fill the bladder prior to administration of
SonoVue® (2.5 ml) to assess the kidney-ureter (K-U) unit.
Dedicated contrast detection software was used to discern
the presence of microbubbles in the pelvicaliceal system
(PCS). The findings were then compared with MCU.
Results: 27 paediatric patients were involved in the study [17
males (63%) and 10 females (37%)] involving 55 K-U units
(one patient had a complete duplex system). MCU detected
VUR in 10 K-U units while ce-VUS detected VUR in 8 out of
the 10 K-U units. There were 2 false negative cases (both
Grade 1) with ce-VUS. The sensitivity, specificity, accuracy,
positive predictive value, and negative predictive value of
ce-VUS were 80%, 98%, 95%, 89% and 96%, respectively.
Conclusion: ce-VUS is a sensitive and specific radiation-free
alternative for the detection of VUR in the paediatric
population.
Urinary Tract Infections
4.Renal doppler assessment in differentiating obstructive from non-obstructive hydronephrosis in children
Nadzri Misni ; Erica Yee Hing ; Hamzaini Abdul Hamid ; Faizah Mohd Zaki ; Aini AbAziz ; Kanaheswari Yoganathan ; Zulfiqar Mohd Annuar
The Medical Journal of Malaysia 2015;70(6):346-350
background: to determine the usefulness of Doppler
ultrasound measurement of resistive index (RI) in
differentiating obstructive from non-obstructive
hydronephrosis in children.
Methods: From August 2011 to November 2012, renal
Doppler assessments of the intra-renal renal arteries were
performed on 16 children (19 kidneys) with congenital
hydronephrosis. the independent t-test was used to
assess for significant difference in RI values between those
with obstructive hydronephrosis (6 kidneys) and those with
non-obstructive hydronephrosis (13 kidneys) as determined
by dynamic renal scintigraphy. the assessor was blinded to
the clinical findings and scintigraphy results.
Results: RI was significantly different between obstructive
and non-obstructive hydronephrosis. Obstructive
hydronephrosis returned higher RI values, with mean RI of
0.78. Mean RI in non-obstructive hydronephrosis was 0.70,
and the difference was significant (p <0.05). the sensitivity
and specificity of Doppler ultrasound were 100% and 53%
respectively.
conclusion: Doppler ultrasound measurement of resistive
index is useful in differentiating obstructive from nonobstructive
hydronephrosis and provides an alternative
non-ionizing investigation other than dynamic renal
scintigraphy.
5.Comparison on the use of semi-automated and automated core biopsy needle in ultrasound guided breast biopsy
Radhika Sridharan ; Shereen Mohd Yunos ; Suraya Aziz ; Rizuana Iqbal Hussain ; Sharifah Majedah Idrus Alhabshi ; Suria Hayati Md Pauzi ; Saladina Jaszle Jasmin ; Zulfiqar Mohd Annuar
The Medical Journal of Malaysia 2015;70(6):325-333
Objective: The aim of this study was to compare the use of
semi-automated (Medax Velox 2; Poggio Rusco, Italy) and
automated (Bard Magnum Biopsy Instrument; Covington,
GA, USA) core biopsy needles, for ultrasound guided breast
biopsy.
Materials and Methods: A 14G semi-automatic spring loaded
core biopsy needle with a 22-mm-throw (Medax Velox 2;
Poggio Rusco, Italy) and 14-gauge automated needle device
with a 22-mm-throw biopsy gun (Bard-Magnum Biopsy
Instrument, Covington, GA, USA) were used for breast
biopsies under ultrasound guidance on alternate months
during the study period between July 2009 and May 2011.
One hundred and sixty lesions were biopsied and
specimens were sent for histological evaluation.
Results: The automated needle obtained a higher number of
histology reports at 84% (67/80) as compared with the semiautomated
needle at 60% (48/80) (Fisher exact test, p
value=0.023). Inadequate samples with the automated
needle were much less at 9% (7/60) than with the semiautomated
needle at 23% (18/60) (Fisher exact test, p
value=0.028). The semi-automated needle showed slightly
less fragmented samples. However, the number of
fragmented samples with definitive diagnosis was slightly
higher with the automated compared with the semiautomated
needle, at 16% (13/80) and 13% (10/80)
respectively. Compared with histology of 29 lesions that
were excised, the semi-automated needle had higher
sensitivity (100%) but lower specificity (75%) and accuracy
(90%) compared with the automated needle (88% sensitivity,
100% specificity, 95% accuracy).
Conclusion: Definitive diagnosis from the study samples
slightly favours the use of automated core biopsy needle as
compared to semi-automated core biopsy needle.