1.The character, diagnosis and treatment for early postoperative inflammatory small bowel obstruction
Chinese Journal of Current Advances in General Surgery 1999;0(03):-
Objective :To investigate the character,diagnosis and treatment for early postoperative inflammatory small bowel obstruction (EBSBO). Methods: From April 1997 to May 2000 with 7 cases of EPSBO,their ages ranged form 21 to 59 years old. The time of onset of intestinal obstruction was at 4 to 9 days after operation. We also revieved the recent literature. Results:All patients were initially treated with a nasogastric tube,TPN,Growth hormone,a-drenocortical hormone, somatostatin. Three patients were resolved eftectually and four need operation.of them,one occured intestinal fistula. Conclusion:BPSBO usually occures with in two weeks after operation. The clinical symptomes are vomiting and distention, but less abdominal pain. The reason includs mechanical and motility factores, none sustaines bowel infarction. According to the different causes,conservative treatment is as carried out initially,if nonopera-tian isn't successful .operation should be considered.
2.Expression and implication of Survivin and its correlation with p27~(kipl) in gallbladder cancer
Zongli ZHANG ; Jie CHAI ; Demin MA
Chinese Journal of Current Advances in General Surgery 2004;0(05):-
Objective:To study the expression of Survivin and p27~(kipl)and their relationship with the clinical features of gallbladder cancer.Methods:Fifty specimens of gallbladder cancer,20 specimens of chronic cholecystitis,20 specimens of polypoid lesions of gallbladder(PLG)were included,the expression of Survivin and p27~(kipl)were detected using immunohistochemistry assay.Results:In 50 cases of gallbladder cancer,39 cases expressed Survivin and 22 cases expressed p27~(kipl).There was a negative correlation between the expression of p27 and survivin(P0.05),but the expression of p27~(kipl)was related to the pathological grade,clinical stage and lymph node metastasis of gallbladder cancer(P
3.Expression of hMLH1 and hMSH2 in hilar cholangiocarcinoma and its significance
Zongli ZHANG ; Demin MA ; Yanchao GAO
Chinese Journal of Hepatobiliary Surgery 2008;14(4):272-274
Objective To investigate the expression of hMLH1 and hMSH2 in hilar cholangiocarcinoma and its relation to clinical features and prognosis of the tumor.Methods The expression of hMLH1 and hMSH2 was determined with immunohistochemistry in 54 specimens of hilar cholangiocarcinoma and 25 of normal bile duct tissue.Lahoratory data were then analyzed statistically together with the related clinicopathological data.Results 1)hMLH1 and hMSH2 were expressed in 24 and 21 out of the 54 cases of hilar cholangiocarcinoma(44.4%,38.9%)and 23 and 21 of the 25 normal cases(92%,84%),respectively(P<0.05).2)The expression of hMLH1 and hMSH2 in hilar cholangiocarcinoma had no association with the age,gender,tumor size and Bismuth type(P>0.05)but close relation to lymph node metastasis and pathological changes(P<0.05).3)The 2-year survival rate was markedly lower in hMLH1-negative patients than in hMLH1-and hMSH2-positive ones (15%vs.45.4%,23.5%vs.44%,P<0.05).Conclusions Joint action of hMLH1 and hMSH2plays an important role in the oncogenesis and metastasis of hilar cholangiocarcinoma.These two may be valuble factors to indicate prognosis of the tumor.
4.Expression of TFIIB-related factor 2 protein in human hepatocellular carcinoma and its clinical significance
Lijie ZHENG ; Yanchao GAO ; Zongli ZHANG
Chinese Journal of Hepatobiliary Surgery 2014;20(4):290-293
Objective To study the expression of TFIIB-related factor 2 (BRF2) in hepatocellular carcinoma(HCC) and to determine its clinical significance.Methods 80 HCC patients who received ‘curative' hepatectomy at the Qilu Hospital were studied.Immunohistochemistry analysis was performed to examine the expression of BRF2 and CD34 (microvessel density) in tumor tissues,matched paraneoplastic tissues,and normal liver tissues.Statistical methods were performed to analyse the relationships of expressions of BRF2 and CD34 with clinicopathologic factors.Results BRF2 protein was expressed at a high rate of 61.3% in HCC tumor,which was significantly higher than that in normal liver tissues and matched paraneoplastic tissues (31.6%,28.8 %,respectively,P < 0.05).BRF2 was significantly associated with tumor differentiation,number of nodules,tumor encapsulation,TNM stage,and microvessel density.Prognosis of the high expression BRF2 group was poor.The recurrence and metastasis rates in the high expression group were significantly higher than the low expression group (P < 0.05).The survival rate in the high expression group was significantly lower than the low expression group (P < 0.05).Conclusions The expression of BRF2 increased in HCC tissues,and its expression was closely associated with pathological features and prognosis of patients,indicating that it can be used as a predictor in assessing prognosis of patients with HCC.
5.Differences in angiogenesis and its maturation of hepatocellular carcinoma between in tumor periphery and in center
Dexin YU ; Zongli ZHANG ; Xiangxing MA ; Xiaoming ZHANG
Chinese Journal of Current Advances in General Surgery 1999;0(02):-
Objective:To study the differences in angiogenesis and its maturation between the periphery and center. of hepatocellular carcinoma (HCC). Methods:Thirty-one cases proved surgically and pathologically were selected. After surgery, two sections were gotten from the tumor periphery and center. Continuous slices were stained with immunohistochemistry of five antibodies against VEGF, Flk-1, PCNA.The expressions of VEGF,Flk-1, and PCNA, and some vascular parameters were counted including the number, mean area, total area, circumference, diameter, distance between adjacent vessels(DAV), variety index of microvessel and mature vessels. The arterioles , veinlets, mature vessel index and mean perfused fraction (mPF)were also calculated. The differences of the vascular parameters above between the periphery and center were analyzed. Results: The differences in the number, diameter, and variety index of microvessel, the number and total area of mature vessel, the arterioles and the ratio of arteriole or veinlet, mature vessel index and mPF were statistical differences between the periphery and center of the tumor (P
6.Evaluation of liver function status in patients with obstructive jaundice using in vivo 31-phosphorus magnetic resonance spectroscopy
Dexin YU ; Xiangxing MA ; Xiaoming ZHANG ; Zongli ZHANG
Chinese Journal of Current Advances in General Surgery 1999;0(04):-
Objective: To evaluate the liver function status in patients with obstructive jaundice using in vivo 31-phosphorus magnetic resonance spectroscopy (31P-MRS). Methods:31P-MRS scan with a single voxel on hepatic parenchyma was carried out in 31 patients with obstructive jaundice and in 40 healthy controls. Intracellular pH value (pHi), and some metabolic parameters including phosphomonoester (PME), phosphodiester (PDE), inorganic phosphate (Pi), ?-ATP, ?-ATP, ?-ATP, lower energetic phosphate (LEP), and the ratios of PME/ATP, Pi/ATP, PME/PDE, PME/Pi, PDE/Pi and PDE/ATP were calculated. Serum markers of liver function including AST, ALT, TBIL, DBIL, IBIL, TP, ALB, GLO, A/G, ALP and GGT were also recorded. The relationship between themwas analyzed. Results: 31P-MRS showed an increase in PME, PDE, PME/ATP, PME/Pi, PDE/ATP and LEP in jaundice patients compared with controls (P
7.Rediscussion on significance of military medical equipment third-class servicing station
Zujin ZHANG ; Zhaoping GUO ; Hui LI ; Zongli ZHANG
Chinese Medical Equipment Journal 2004;0(09):-
Based on abundant experiences on circuit servicing of medical equipment in frontier defending military units,this paper discusses the significance of military medical equipment third-class servicing station again and provides solutions to some problems in work.
8.Application of argon-fluoride excimer laser to corneal refractive surgery
Zujin ZHANG ; Zhaoping GUO ; Runqiang WU ; Jiaping YUAN ; Zongli ZHANG
Chinese Medical Equipment Journal 2003;0(11):-
In this paper,such information of argon-fluoride excimer laser is introduced as its principle,capacity,features and application to corneal refractive surgery.Its treatment effects and developing trend are also mentioned.
9.Comparative analysis of predictive value of different inflammatory markers for the severity of community-acquired pneumonia in adult and elderly patients
Zongli LI ; Changhong ZHANG ; Xiaorong LI ; Zuoqing ZHANG
International Journal of Laboratory Medicine 2015;(19):2808-2809
Objective To evaluate the predictive value of procalcitonin (PCT),C-reactive protein (CRP)and white blood cell (WBC)for the severity of community-acquired pneumonia(CAP)in adult and elderly patients.Methods A total of 1 12 hospitalized patients with community acquired pneumonia from May 2013 to September 2014 were selected,and they were divided into the adult group(n=50)and the elderly group (n =62).The PCT,CRP and WBC levels in patients with severe and non-severe pneumonia were compared,and the correlation between those inflammatory markers and pneumonia severity index (PSI),British Thoracic Soci-ety CURB-65 Score(CRUB-65)were analyzed in each age group.Results PCT and CRP levels,PSI and CURB-65 scores in adult and elderly patients with severe pneumonia were higher than those in patients with non-severe pneumonia of corresponding age group (P < 0.05 ).Moreover,PCT had significant positive correlation with PSI and CURB-65 scores in the elderly group (P <0.05).But no correlation were found between the two kinds of scores and PCT in adult group as well as CRP,WBC in the two age group(P >0.05).Conclusion PCT and CRP might be useful markers to evaluate the severity of CAP,and PCT has a higher pre-dictive value in elderly patients with CAP.
10.Design and application of an automatic ventilation system for excimer laser therapeutic instrument
Zujin ZHANG ; Zhaoping GUO ; Runqiang WU ; Jiaping YUAN ; Zongli ZHANG
Chinese Medical Equipment Journal 2004;0(07):-
In this paper, the constitution and operation principle of an automatic ventilation system for excimer laser therapeutic instrument are introduced. With high accuracy, stability and reliability, the system benefits the performance and service life of the instrument.