1.Simulation analysis of skin hyperthermia with non-isothermal heating
Shaofeng JIANG ; Guangqi LIU ; Jintian TANG ; Zihan ZHUO ; Li FENG ; Xiaodong ZHANG
International Journal of Biomedical Engineering 2013;(1):17-21
Objective Skin disease is multiple,common disease,and there are so many therapeutic methods.In recent years,physical non-invasive therapy of skin disease has developed rapidly.On the basis of Pennes equation,a series of simulation analysis was completed,and the results confirmed the feasibility and availability as well as the definite safety of curing skin diseases by direct heating.In order to achieve the maximum efficacy and the minimum side effects simultaneously and based on the previous research,exploratory simulation experiment of non-isothermal heating was carried out.Methods The skin temperature fields with non-isothermal heating were simulated by utilizing mathematical tools (Matlab).Results Compared to the previous isothermal heating,during the non-isothermal heating,the temperature of inner skin displayed the rising trend,while it displayed the declining trend during the isothermal heating.Conclusion As compared to isothermal heating,non-isothermal heating has better restraining effect for the bacterium within the inner skin,and less side-effect.
2.Research on integrated application of tumor magnetic induction hyperthermia treatment planning system and modern medical information systems.
Zihan ZHUO ; Weiming ZHAI ; Dongyang CAI ; Jie WANG ; Xiaodong ZHANG ; Jintian TANG
Journal of Biomedical Engineering 2014;31(1):187-191
Magnetic induction hyperthermia becomes a very important tumor treatment method at present. In order to ensure a successful operation, doctors should make hyperthermia treatment planning before surgery. Based on Integration Healthcare Enterprise (IHE) framework and Digital Imaging and Communications in Medcine (DICOM) standard, we proposed and carried out a network workflow integrated with modern medical information systems for the dissemination of information in magnetic induction hyperthermia like accurate accessing patient information and radiology image data, storing processed images, sharing and verifying hyperthermia reports. The results proved that our system could not only improve the efficiency of magnetic induction hyperthermia treatment planning, but also save medical resources and reduce labor costs.
Humans
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Hyperthermia, Induced
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Image Processing, Computer-Assisted
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Magnetic Phenomena
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Neoplasms
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therapy
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Radiology Information Systems
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Systems Integration
3.Progress of Quantitative MRI Research on Fetal Myelin Development
Zihan HONG ; Mengying YANG ; Jinqin LI ; Yanling ZHANG ; Zhuo WANG ; Bing CHEN
Chinese Journal of Medical Imaging 2024;32(8):855-859
Human myelination begins in the fifth month of fetal development and continues after birth.Myelin development plays a key role in establishing and maintaining information conduction,coordination and communication within the brain,so prenatal quantitative assessment of myelin development is important.In recent years,many MRI techniques for myelin imaging have been developed and implemented,and quantitative MRI assessment of fetal myelin development has received increasing attention.In this review,we discuss the known structural and functional changes in the development of the myelin sheath of the fetal central nervous system,and review the research progress and future expectations of quantitative fetal MRI imaging.