1.Analysis of cranial decompression under temporal muscle in very-low position with large bone flap combined with mild hypothermia for severe cranial trauma
Tao SUN ; Zhurong ZHENG ; Shouwu LIU ; Yiqiang XIONG ; Yang CHENG
Chinese Journal of Primary Medicine and Pharmacy 2012;19(9):1316-1317
Objective To investigate cranial decompression under temporal muscle in very-low position with large bone flap combined with mild hypothermia for severe cranial trauma.Methods 88 severe brain injury patients (GCS ≤ 8 ) were randomly divided into two groups,mild hypothermia group( n =48) and non-mild hypothermia group ( n =40),both presented with cranial decompression under temporal muscle in very-low position with large bone flap.Data of patients,GCS increment,rate of brain cistern display,rate of pupil shrink and therapeutic effect were ananlyzed.Results The treatment group showed better effect compared with the oontrol group(P<0.05).Condusion The therapy of cranial decompression under teniporal muscle in very-low position with large bone flap combined with mild hypothennia showed the advantage of depressing intracranial pressure,reducing crerebral edema and improving the therapeutic effect of severe brain injury patients.
2. The effect on myocardial perfusion and clinical outcome of intracoronary nicorandil injection prior to percutaneous coronary intervention in ST-segment elevation myocardial infarction
Zhiqing WANG ; Meixian CHEN ; Donglin LIU ; Weixing ZHENG ; Xiaozhi CAO ; Hao CHEN ; Mingfang HUANG ; Zhurong LUO
Chinese Journal of Cardiology 2017;45(1):26-33
Objective:
To investigate the effect of intracoronary administration of nicorandil prior to primary percutaneous coronary intervention (PPCI) on myocardial perfusion and short-term clinical outcomes in patients with ST-segment elevation myocardial infarction (STEMI).
Methods:
A total of 158 patients with STEMI undergoing PPCI from January 2014 to December 2015 in Fuzhou General Hospital were enrolled consecutively in this prospective controlled randomized trial. Patients were assigned into three groups with random number table: the nicorandil group (patients received intracoronary administration of 6 mg nicorandil after guide wire or balloon successfully crossed the target lesion,