1.Comparison of the effect of D-TBL and LBL teaching methods in the teaching of national medicine
Zhenzhi MENG ; Jiaona LAN ; Zhuofei MA ; Xiufeng HUANG
Chinese Journal of Medical Education Research 2016;15(8):812-815
Objective To discuss task-based learning and team-based learning methods and lecture-based learning method in the class of ethnic medicine.Method 50 students in clinic medicine (general practice) of grade 2012 were selected as D-TBL group and 54 students in clinic medicine of grade 2013 were selected as LBL group.Both groups have teaching content,textbook,teachers,class hours in common.Effect of teaching was valued by tests,evaluation in students,questionnaires.SPSS was used to analyze scores of tests.T test was used.Results The correct answer rate?of subject items in D-TBL group was higher than that of LBL group and the difference had statistical significance [(94.56 ± 4.95)% vs.(29.26 ± 12.15)%,t=36.382,P=0.000).There was no significant difference between the correct answer rate of personal test in D-TBL group and objective item in the LBL group[(75.20 ± 11.82)% vs.(68.61 ± 14.65)%,t=2.512,P=0.374].There was no statistically significant difference between the correct answer rate of group test in D-TBL group and objective item in the LBL group[(84.25 ± 13.08)% vs.(68.61 ± 14.65)%,t=5.727,P=0.961].In Score table for members in every division,41(85.42%) students got straight A,7(14.58%) students got B and nobody got C.Feedback questionnaire showed 40(83.33%) students like D-TBL while 26(50.00%) students like LBL.Conclusion Most of students in D-TBL group like D-TBL.D-TBL and LBL cannot take the place of each other.In the future teaching,both methods should be used in different teaching periods according to their merits.
2.Effect of erythropoietin on chemo-sensitivity of pancreatic cancer cell line SW1990 to gemcitabine
Qiong YANG ; Derong XIE ; Zhimin JIANG ; Denglin CHEN ; Zhuofei BI ; Wen MA
Chinese Journal of Pancreatology 2009;9(3):178-180
.036;r=-0.968,P=0.032).Conclusions Epo might decrease the chemo-sensitivity of SW1990 to gemcitabine possibly by up-regulating the expressions of MDR-1 and RRM1.
3.Association between Hepatitis B Virus Infection and Pancreatic Cancer
Wen MA ; Derong XIE ; Wanping CAO ; Qiong YANG ; Zhimin JIANG ; Denglin CHEN ; Zhuofei BI ; Yuandong ZHANG
Chinese Journal of Clinical Oncology 2009;36(24):1388-1390
Objective: To analyze the association between hepatitis B virus (HBV) infection and pancreatic cancer. Methods: Retrospective analysis was performed to explore the positive rate of serum hepatitis B virus surface antigen (HBsAg) in patients with pancreatic cancer, lung cancer, diabetes mellitus and general population. Z test was used to compare the rate of HBV infection between the samples and general population. The rates among the samples were compared by Chi-square test. Results: A total of 3,701 registered patients seen in our hospital between January 1st 2003 and March 31st 2009 were collected. There were 230 pancreatic cancer patients with a positive rate of serum HBsAg of 16.1%, 1,188 lung cancer patients with a positive rate of serum HBsAg of 10.7%, and 2,283 patients with diabetes mellitus with a positive rate of serum HBsAg of 11.6%. There was no statistical significance in Z-test results between lung cancer patients and general population (Z=1.104, P=0.163), but the Z-test results between patients with diabetes mellitus and general population showed a statistical significance (Z=2.98, P=0.002). The positive rate of HBsAg was higher in pancreatic cancer patients than that in lung cancer patients (OR=1.60, 95% Cl: 1.077-2.382, r=5.487, P=0.019). Similar results were found between pancreatic cancer patients and diabetic patients (OR=1.46, 95% CI: 1.004-2.123, r=3.965, P=0.046). Conclusion: The positive rate of HBsAg is high in pancreatic cancer patients. There might be an association between HBV infection and pancreatic cancer.