Object To determine the activities of various antioxidant enzymes, including superoxide dismutase, catalase, peroxidase and glutathione peroxidase, and the contents of some simpler antioxidants such as glutathione, chlorogenic acid and certain flavonoids in the leaves, stems and fruits of Viscum coloratum (Kom ) Nakai Methods The activities were determined as described in various literature reports Results The plant was found to be rich in various antioxidants Conclusion V coloratum, with its abundant antioxidant constituents, is proved to be a strong antioxidation drug for medical use especially its leaves

OBJECTIVETo study the constituents of the whole herbs of Vernonia cinerea by bio-activity guided isolation with PC-12 model.

METHODThe constituents were separated by column chromatography and the structures were elucidated by spectroscopic methods.

RESULTTen compounds were identified to be (-)-clovane-2,9-diol (1), caryolane-1,9beta-diol (2), apigenin (3), chrysoeriol (4), luteolin (5), thermopsoside (6), luteolin-7-O-beta-D-glucoside (7), quercetin(8), apigenin-4'-O-beta-D-glucoside (9), hyperin (10), beta-amyrin aceate (11), lupeol acetate (12).

CONCLUSIONCompounds 1, 2, 6 and 10 were isolated from this genus for the first time.

Animals ; Drugs, Chinese Herbal ; chemistry ; pharmacology ; PC12 Cells ; Rats ; Vernonia ; chemistry