1.Significance of establishing a corpus of English translation for the TCM health preservation
Chunli LU ; Lilan DU ; Zhufen CHEN
International Journal of Traditional Chinese Medicine 2017;39(1):63-67
This paper discussed and elucidated the significance of establishing a corpus of English translation for the TCM terms of health preservation. To investigate the necessity and feasibility of corpus, we have explored the domestic and international researchs of the data sources and corpora and translation of TCM terms. We also predicted the prospect of application of this corpus.
2.Study on explicitation in English translation of TCM pathogenesis terms
Lilan DU ; Aijuan LIU ; Zhufen CHEN
International Journal of Traditional Chinese Medicine 2014;(12):1115-1119
English translation of TCM pathogenesis terms was investigated in this paper from the perspective of universal features of translation. Small-sized Chinese and English parallel corpus of TCM pathogenesis terms was built to examine whether English translation of TCM pathogenesis terms bore the features of explicitation. Further study was conducted to investigate expliciatation revealed in different versions. Results showed that explicitation exists in the English translation of this field, consistent with Blum-Kulka’s (1986) Explicitation Hypothesis. At the same time, explicitation in English translation of TCM pathogenesis terms possesses its own characteristics. First, its pattern is different from that of literary works. There are mainly three types of explicitation, i.e. adding words, specifying, and explicitation of analogy/metaphor. Among these types, adding words is the most frequently used. In addition, more cases of explicitness are found in Chinese translators’ versions than those of foreign ones, which might be due to the different translation principles held by different translators. The unique philosophy of TCM is substantially different from that of western medicine, thus its unique way of expression may lead to the phenomenon of explicitation in English translation of TCM pathogenesis terms. The present study provides fresh evidence for the Explicitation Hypothesis.
3.Investigation into format of bilingual package inserts of Chinese medicine
Aijuan LIU ; Lilan DU ; Xiaoli LI ; Zhufen CHEN
International Journal of Traditional Chinese Medicine 2015;(11):961-966
A data-based quantitative study was conducted by examining 43 bilingual package inserts of Chinese medicine. The results indicated that most inserts were poorly constructed with incomplete formats. Furthermore, there seemed no standardized translationforthe section titles, and some of them were even translated incorrectly. It was suggested that insert translation should follow the “reader-centered principle” which was determined by its communicative purpose. Translators should take full advantage of intertextual reference and construct complete and standard insert formats of Chinese medicine, thus helping readers obtain information more quickly and easily. This paper intends to advance some suggestions concerning the text constructionof bilingual package inserts of Chinese medicineand help enterprises in this line increase their competitiveness in the international market.
4.Advances of new excipients and technique in colon-specific preparations
Shina SU ; Zhufen LYU ; Chaofeng LIANG ; Kewei LU ; Yunran HUANG ; Yanzhong CHEN
Journal of China Pharmaceutical University 2017;48(2):242-250
The oral colon-specific drug delivery system (OCDDS) has gained more attention from investigators in recent years since it can increase local drug concentration and reduce dosage and side effects.The type of colonspecific drug delivery system consists of enzyme dependent,pH dependent,time dependent,pressure dependent system and CODEDSTM.The development of many new materials and technology is very important for the preparation of new type of precise positioning colon-specific preparation.This article summarizes the advances in excipients and technique for oral colon-specific drug delivery system in recent years.It may provide a reference and a basis for the researchers concerned.
5.Transnasal endoscopic repair of nasal septal perforation with pedicled muscle-periosteum flap from anterior wall of the maxillary sinus.
Xiang-ling WEN ; Xian-long LI ; Chen-gang WANG ; Hongliang YANG ; Linling ZHU ; Yongfu LI ; Li LU ; Ping CHEN ; Zhufen ZHAO
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2006;41(1):68-69
Adult
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Endoscopy
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Female
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Humans
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Male
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Maxillary Sinus
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surgery
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Nasal Septum
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injuries
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surgery
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Periosteum
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transplantation
6.Optimization of the Formulation of Polygala japonica Cream by Central Composite Design-response Surface Methodology Based on AHP-CRITIC Analysis and Its Quality Evaluation
Xue’e LI ; Shu ZHANG ; Hong DENG ; Zhufen LYU ; Yulin TAN ; Jiamin CHEN ; Yushan YU
China Pharmacy 2020;31(21):2615-2621
OBJECTIVE:To optimize the formul ation of Polygala japonica cream,and to evaluate the quality of prepared cream. METHODS :With centrifugal stability ,heat resistance stability and viscosity as evaluation indexes ,the weight coefficient was determined by analytic hierarchy process (AHP),criteria importance through intercriteria correlation (CRITIC)method and mixed weighted AHP-CRITIC ,and the comprehensive score was calculated. The amount of octadecyl alcohol ,hexadecanol and mixed emulsifier (polysorbate 60 mixed with glycerin monostearate at the mass ratio of 2.82)in the formulation of P. japonica cream were screened by central composite design-response surface methodology. The optimized formulation was validated. P. japonica cream prepared by the optimal preparation was evaluated in terms of apperance ,particle,pH,stability and rheological characteristics. RESULTS :The weight coefficients of centrifugal stability ,heat resistance stability and viscosity were 0.428 5, 0.415 6 and 0.155 9 respectively,according to the mixed weighted AHP-CRITIC. The optimal formulations were 1.96 g of hexadecyl alcohol ,5.17 g of octadecyl alcohol ,2.48 g of mixed emulsifier ,1.83 g of polysorbate 60,0.65 g of glyceride monostearate,1 g of benzyl alcohol ,5 g of propylene glycol ,6 g of isopropyl myristate and 5 g of P. japonica extract,and then added water to 100 g. Prepared cream was a light yellow fluid paste with particle size of 0.5-2.5 μm and pH value of 6.5;the results of centrifugal test ,heat resistance test and cold resistance stability test showed that the cream had no oil-water separation or thickened paste. The prepared cream was shear-thinning non-Newtonian fluid. CONCLUSIONS :P. japonica cream is prepared successfully,which shows good apperance ,particle,acidity and stability.
7.Preparation and Quality Evaluation of Imperatorin Ultradeformable Liposomes Gel
Xuehui CUI ; Shihong CHEN ; Jindi QIU ; Junfeng BAN ; Nannan YANG ; Qingchun NI ; Zhaoyan PAN ; Qingchun XIE ; Yanzhong CHEN ; Zhufen LYU
China Pharmacy 2020;31(9):1074-1079
OBJECTIVE:To prepare Imperatorin ultradeformable liposomes gel (IMP-UDLs-Gel),and to evaluate its quality. METHODS:Based on single factor test ,using 12 h accumulative penetration amount (Q12h)as evaluation index ,the proportion of carbomer 940,glycerol and propyl glycol in formulation of IMP-UDLs-Gel were investigated by orthogonal test. The optimal formulation was screened. The quality of IMP-UDLs-Gel prepared with the optimal formulation was evaluated. RESULTS :The optimal formulation of IMP-UDLs-Gel included carbomer 940 proportion of 1%,glycerol proportion of 15% and propyl glycol proportion of 10%. Q12 h of IMP-UDLs-Gel was (11.543±0.241)μg/cm2;the appearance was milky white and translucent ;the particle size was (93.13±1.68)nm,PDI was 0.268±0.012,Zeta potential was (-24.96±1.99)mV;pH was 7.32±0.03; viscosity was (45.37±1.27)g·s;steady flow was (0.727±0.002)μg·h/cm2,lag time was (4.358±0.175)h,apparent permeability coefficient was 1.392×10-3 cm/h,and it has good physical and optical stability. CONCLUSIONS :The preparation method is stable and feasible ,and the prepared IMP-UDLs-Gel has good adhesion ,stability and transdermal property.