This paper introduced the current situation of the talent training system of French nursing college, including enrollment conditions, length of schooling, training objectives, teaching methods, curriculum framework, etc., in order to explore the way of localization of nursing talents training reform, and hope to further strengthen the cooperation and training of colleges and universities, to explore the diversified enrollment mode of students,to deepen the training mode guided by working competence, and to enhance unique and internationalization of Nursing courses.

Ethmo-maxillary bone buttress (EMBB) is a special complex bone structure in the interface between the internal wall and inferior wall of the orbit, which plays a vital role in maintaining the stability of the orbit, ethmoidal sinus and maxillary sinus.Although the incidence of compound fractures in orbital blowout fractures is lower than that of single orbital wall fractures, they have more obvious clinical symptoms such as enophthalmia and binocular diplopia.The mechanism of EMBB may be more supportive of the orbital floor compression theory, that is, the external force will lead to torn periostum and bone seam separation at the ethmoidomaxillary suture, and the orbital contents will form a funnel-like hernia due to extrusion and gravity.Or the extrusion results in the fracture and displacement of the orbital lamina of ethmoid bone, the upper wall of the maxilla and the ethmoidomaxillary plate, causing a large area of orbital wall collapse and obvious expansion of the orbital cavity.Recently, the study of orbital internal wall and inferior wall joint fracture has become a new hotspot, but research on the orbital blowout fracture involving ethmo-maxillary bone buttress is still in its infancy.The current orbital fracture repair technique can only restore the connection between the two orbital walls, and there is no surgical plan can overall recover EMBB's scaffolds role.Therefore, how to restore the scaffolds role of EMBB, and to regain the part of ostiomeatal complex in normal sinus drainage is the challenge we need to conquer.In this article, the anatomy and clinical characteristics of the supporting structure, fracture mechanism, and the research progress and prospect of surgical repair technique were reviewed.

CYP3A plays central roles in the oxidative and reductive metabolism of a variety of enogenous as well as exogenous compounds, it is very important to study about regulation of CYP3A geneexpression. This article reviews the recent development of molecular mechanism of regulation of CYP3A gene expression and CYP3A mutation. The relationships between CYP3A mutant and some diseases are also introduced.

REG4,as a member of regenerating gene family,involves in proliferation and differentiation of gastrointestinal tract cells.Recent studies have shown that REG4 gene expression is upregulated in gastrointestinal cancer,pancreatic cancer,gallbladder cancer and prostate cancer,and associated with tumorigenesis,metastasis and poor prognosis of these carcinomas.Further studies have indicated that not only does REG4 play an important role in the diagnosis of gastrointestinal carcinoma,but also is closely linked with the effects of radiotherapy and chemotherapy.

Objective To study the deep vein thrombosis (DVT ) in lower extremities of patients with or without cardiovascular disease after fracture .Methods Five hundred and eighty-four frac-ture patients were divided into cardiovascular disease (CVD) group (n=235) and non-cardiovas-cular disease (NCVD) group (n=349) .Patients in CVD group were further divided into subgroup A (with essential hypertension) ,subgroup B (with CHD) ,and subgroup C(accompanying essen-tial hypertension and CHD) .Incidence of DVT in CVD group ,NCVD group ,subgroups A-C at different ages after fracture was compared .Results The incidence of DVT was significantly high-er in CVD group than in NCVD group (P<0 .01) ,in two groups on days 0-7 after fracture than on days 8-14 or >14 after fracture ,and in patients with their age ≥60 years than in those with their age <60 years .Conclusion DVT is easier to occur in CVD patients with their age ≥ 60 years than in those with their age <60 years after fracture .DVT usually occurs within 1 week af-ter fracture .Importance attached to high risk population and measures taken as soon as possible against it can reduce DVT after fracture .

Based on the present situation analysis of nursing experimental teaching for undergraduate,reform was carried out through our innovating experimental teaching philosophy,integrating experimental teaching curriculum,compiling experimental teaching materials,establishing experimental teaching inspection and assessment system and consummating management mechanism of experimental teaching center,and some developing thoughts were also proposed.

Laparoscopic minimally invasive surgery technology is rapidly developing in the tumor treatment field. Due to the lack of space perception of the previous 2 D laparoscopic surgery, it has been unable to meet the current needs, and then 3 D laparoscopic technology emerged and got widely development. This paper summarizes the difference between the 3 D laparoscopic technique and traditional 2 D laparoscopic technology, and then analyzes the classification of 3 D signal display technology and common format. At the same time, this paper introduces the integration operating room structure with 3 d technology, signal format, and signal transmitting method. Finally, this paper prospected the application foreground for 3 D laparoscopic technology in the operating room.

Objective:To observe the clinical effects of acupuncture at Jiaji (EX-B 2) points plus tuina manipulation for thoracic facet joint disorder, and get new clinical evidence for treatment of thoracic facet joint disorder. Methods:Totally 106 patients with thoracic facet joint disorder were randomly allocated into an observation group and a control group based on the random number table. Patients in the control group were treated by tuina manipulation, while those in the observation group were treated by acupuncture at Jiaji (EX-B 2) points before tuina manipulation. Patients in the two groups were treated once a day. The improvements of signs and symptoms and the efficacy were observed after 3 treatments. Results:After treatment, there were intra-group statistical differences in scores of 8 signs and symptoms in both groups (P<0.01); the score of each item in the observation group was lower than that in the control group, and there was statistical significance in the inter-group difference (P<0.05). The cure rate of the observation group was 50.9%, versus 26.4% in the control group, and there was a significant difference between the two groups (P<0.05). Conclusion:In treating thoracic facet joint disorder, acupuncture plus tuina manipulation can restore the biomechanical balance of thoracic vertebrae, fully maximized the combined effect, and significantly improve the clinical efficacy.

The present study, using the different catecholamines, observed the effects on plasminogen activator (PA) activity release in the vascular wall of rat hindlegs. The results showed that adrenaline perfusion induced the highest PA activity in three different catecholamines. Propranolol completely blocked PA activity induced by isoprenaline. PA activity induced by adrenaline or noradrenaline was completely inhibited by propranolol combined with phentolamine. During physiological stress the increase of plasma noradrenaline level was accompanied with higher PA activity. These data indicated that exogenous catecholamines produced a increase of PA activity via ?-adrenoreceptors stimulation mainly, as well as ?-receptors partially. The endogenous increase of catecholamines showed the same effect on fibrinolytie system.

ObjectiveTo investigate the efficacy of intravenous parecoxib combined with femoral nerve block on postoperative analgesia and knee functional rehabilitation in elderly patients following total knee replacement.MethodsForty elderly patients with osteoarthritis schedu[ed for total knee arthroplasty under general anesthesia,aged 65-74 years,weighing 45-90 kg,ASA [Ⅱ,were randomly divided into two groups( n ＝ 20 each).FNB group received femoral nerve blockade for postoperative analgesia ( local injection of 0.25 ％ ropivacaine 25 ml at the end of surgery,repeated every 8 h up to 72 h after surgery).FNB-Pa group received the femoral nerve blockade plus the parecoxib (administered Ⅳ bolus of 40 mg 30 min before the end of surgery,12,24,and 48 h after surgery respectively).Pain was scored at rest or during continuous passive motion using Visual Analog Scale (VAS).The Hospital for Special Surgery (HSS) knee score was determinated before surgery,at 24,48 and 72 h after surgery respectively.Side effects were also recorded in both groups.Results VAS score was significantly lower at rest and during continuous passive motion in FNB-Pa group than in FNB group ( P < 0.05).Compared with baseline value,HSS score increased significantly during postoperative analgesia in both groups( P < 0.05 or 0.01 ).HSS score were significantly higher at 48 h and 72 h after surgery in FNB-Pa group than in FNB group ( P < 0.05).No severe related side effects occured in both groups.ConclusionFemoral nerve block in combination with intravenous parecoxib can safely and effectively relieve the static and dynamic pain after total knee replacement and is helpful for rehabilitation of the prosthesis knee joint function after surgery.