1.Clinical observation on treatment of mycoplasma pneumonia in children by modified San'ao Decoction combined with Azithromycin
Chinese Journal of Biochemical Pharmaceutics 2017;37(6):76-77,80
Objective To observe the clinical effect of Sangao Decoction combined with Azithromycin in the treatment of mycoplasmal pneumonia in children.MethodsFrom August 2013 to August 2014, 76 children with mycoplasma pneumonia were enrolled in this study.The patients were randomly divided into observation group and control group.The control group was treated with azithromycin alone, and the observation group was given the treatment of Sanao Decoction on the basis of the control group.Comparison of the two groups of clinical efficacy, fever time, cough time, tonsil disappearance time, lung rales disappear time, length of stay and the incidence of adverse reactions.ResultsThe effective rate was 94.37% in the observation group and 76.32% in the control group, which was statistically significant (P<0.05).(2.45±0.90) d, duration of coughing (5.37±1.67) d, duration of disappearance of tonsil (6.23±2.47) d, disappearance of rales (7.18±1.58) d, duration of hospital stay (10.26±1.65) d were shorter than the control group, which was statistically significant (P<0.05).The incidence of adverse reactions was not statistically significant.ConclusionThe effect of Sangao Decoction combined with azithromycin in the treatment of mycoplasma pneumonia in children can significantly shorten the symptoms and signs of the patients, the time of disappearance of the signs and the length of hospital stay, promote the rapid recovery of children, high safety, and have good clinical application value.
2.Effect and safety of gamma globulin combined with glucocorticoid pulse therapy on serum CRP in children with refractory mycoplasma pneumonia
Chinese Journal of Biochemical Pharmaceutics 2017;37(4):26-27,30
Objective To investigate the effect of gamma globulin combined with glucocorticoid pulse therapy in the treatment of children with refractory mycoplasma pneumonia in CRP and safety.Methods 46 cases of children with refractory mycoplasma pneumonia from February 2012 to February 2016 were selected and randomly divided into the control group and experimental group,23 cases in each group.On the basis of the regular treatment,the control group was given azithromycin,10mg/kg,qd,intravenous drip,on the basis of the control group treatment,the experimental group was treated with methylprednisolone 2mg/kg+human immunoglobulin 400mg/kg,qd,intravenous drip.The levels of serum C-reactive protein(CRP),white blood cell count(WBC),lymphocyte count(LC),therapeutic efficiency and safety were measured before and after treatment.Results After treatment,compared with the control group,the serum levels of CRP、WBC、LC were lower in the experimental group,the difference was statistically significant(P<0.05).The treatment efficiency of the experimental group(91.31%)was significantly higher than that of the control group(65.22%),the difference was statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups.Conclusion The gamma globulin combined with glucocorticoid pulse therapy can significantly reduce the serum levels of CRP,WBC and LC in children with refractory mycoplasma pneumonia,improve clinical efficacy and the safety were good.
3.Application of gabapentin in the treatment of neuropathic pain
International Journal of Cerebrovascular Diseases 2015;23(11):859-862
As an anti-epilepsy drug,gabapentin plays an important role in the treatment of neuropathic pain through a variety of central and peripheral mechanisms.Studies have shown that gabapentin has better efficacy for post-stroke pain,spinal cord injury-related pain,postherpetic neuralgia,and pain in diabetic peripheral neuropathy.For mild adverse effects,good tolerance and lack of interactions,gabapentin is an ideal drug for the treatment of neuropathic pain.
5.Research on the design of management system for pathological sample library
China Medical Equipment 2015;(1):54-56
Objective:To establish the pathological sample database and standardize pathology specimen management processes to provide a platform for the study of pathology samples. Methods: Using J2EE, JSP, and component object model technology, the system establish the pathological sample library work platform for the pathology network resources, documentation, and intelligent. Results:The system established pathology samples and workflow management system architecture for the collection, storage and analysis of pathology specimens. Conclusion:The system designed to enhance the authenticity and credibility of the sample test results, thereby improve the accuracy of the sample analysis and provides a good reference for information technology-related departments.
6.Treatment of 53 Cases of Facial Spasm with Acupuncture
Journal of Acupuncture and Tuina Science 2009;7(4):233-234
Fifty-three patients with facial spasm were treated by acupuncture therapy. Taichong (LR 3), Fengchi (GB 20), Yifeng (TE 17), and Sanyinjiao (SP 6) were selected as main points, and others points were selected based on symptom. Of the 53 cases, 9 cases were cured,13 cases were markedly effective, 27 cases were effective, and 4 cases were ineffective, with an effective rate of 92.5%.
7.Dose-effect of dexmedetomidine in reducing restlessness after anesthesia
Clinical Medicine of China 2014;30(11):1124-1126
Objective To investigate the different doses of dexmedetomidine on reducing the effects of restlessness after anesthesia.Methods Forty-eight patients who occurred restlessness after general anesthesia were collected and randomly divided into A,B,C group (16 cases in each group).Dexmedetomidine were given at dose of 0.3 μg/kg,0.5 μg/kg,1.0 μg/kg for treatment as A,B,C group.Blood pressure,heart rate,Riker sedation-restlessness (SAS) score and other changes of patients were recorded at different time points after treatment.Results SAS scores were significantly lower in B,C groups than that in A group (P < 0.05) at immediately after administration and 5 min and 10 min after administration.Systolic pressure and heart rate were significantly lower in C group than in B,A group (P < 0.05) at immediately after administration and 5 min after administration.Only the heart rate in B group at immediately after administration was lower than that in A group.Time in the recovery room in B group was (37.5 ± 6.4) min,significantly lower than A group and C group ((43.2 ± 8.9) min,(47.5 ± 9.8) min ; F =14.362 ; P < 0.001).Conclusion Dexmedetomidine is a more ideal sedation drug and 0.5 μg/kg dexmedetomidine can reduce restlessness and cardiovascular reactions in patients with restlessness after general anesthesia,which is the best recommending therapeutic dose.
8.Discussion on the characteristics and reason of Chinese medicine foreign exchange activities among government organizations in the past nearly 30 years
International Journal of Traditional Chinese Medicine 2015;(8):673-675
As a principal part of foreign exchange activities of traditional Chinese medicine, government organizations played a crucial role. At present, there are relatively rare researches on foreign exchange activities of traditional Chinese medicine in government organizations. In this article, we defined related government organizations and their functions, analyzed the features of the foreign exchange activities of traditional Chinese mdicine among government organizations in the past nearly 30 years. And based on this analysis, SWOT theory model in management science was introduced to discuss the reasons of government behaviors and put forward suggestions for the future development.
9.Survey on training programs of Shanghai General Practice Teacher Training Center
Chinese Journal of General Practitioners 2013;12(10):804-807
Objective To assess training programs from trainees of Shanghai General Practice Teacher Training Center for further improvement.Methods Total 171 trainees attending the GP teacher training program in April,2012 were selected for survey.A self-designed questionnaires were adopted in the survey.The rationality of the curriculum and training contents in the program were analyzed.Results Among 170 trainees who answered the questionnaires,86 of them (51%) considered the training curriculum as very appropriate,76 of them (9%) considered as appropriate; 97 of them (57%) thought the training forms as very vivid,65 of them (38%) thought as vivid.The overall evaluation score for teachers was 4.64.Ninety three of the 170 trainees (55%) expressed a great willingness for training,70 (41%) expressed as willingness.Among 170 trainees 156 (92%) preferred to learn new advances in medicine,111 (65%) preferred to learn teaching skills and theories in general practice.Thirty two trainees (19%) considered that the contents of training met the trainees' needs completely,129 (76%)considered that most contents of training met the trainees' needs.Eighty two (48%) considered that they gained a lot after the training,80 (47%) considered that they gained fairly.The survey showed that 147 (86%) believed the training had broadened their minds,104 (61%) believed the training had increased their capabilities of clinical diagnosis and treatment; 53 (31%) thought the training helped raise their theoretical level.Eighty seven (51%) were very satisfied and 75 (44%) were comparatively satisfied with the training in overall evaluation.Conclusion The training program provided by Shanghai General Practice Teacher Training Center is basically satisfactory and trainees are benefited from the training considerably.
10.Ethics of the donation after cardiac death
Chinese Journal of Digestive Surgery 2013;12(9):644-647
Donation after cardiac death (DCD) means organ harvest and donation cannot be carried on until the requirement of death criteria using cardiopulmonary arrest is reached.Great success has been achieved since DCD was promoted widely in China.However,some problems were encountered during the implementation of DCD and there also exists many ethical controversies.The ethical principles of informed consent and no harm mentioned inDonation after Cardiac Death Work Instructions of China should be strictly adhered to,while justice,fairness and openness must be ensured in organ allocation.Appropriate compensation should be given to DCD donor and his family,and the utilization of DCD should be further improved.All of these ethical principles will help to promote the healthy development of organ donation and transplantation in China.