〔Abstract〕 The paper elaborates the devolopment background of malignant tumor main diagnosis ICD selection module, embeds this module into Electronic Medical Records ( EMR) ystem, introduces design basis, principles and ideas, analyzes the operation process and module functions.It also points out that this module could assist doctors to fill in the diagnostic information of malignant tumor pa-tients, provide better services for clinical, scientific research and management through examples.

Diabetes mellitus( DM)affects almost the whole digestive tract. Approximately 75% of the diabetic patients suffer from gastrointestinal motility disorders. The precise mechanism of diabetic gastrointestinal motility disorders is not fully clear. Its pathogenesis is considered to be multifactorial and related with autonomic neuropathy,smooth muscle myopathy and lesions of interstitial cells of Cajal. Advanced glycation end products( AGEs ) are derived from the nonenzymatic reaction of glucose with proteins,lipids or nucleic acids in vivo. Hyperglycemia in DM is a favourite for formation of AGEs, and excessive accumulation of AGEs contributes to the complications of DM such as diabetic nephropathy and diabetic vascular lesions. However,the correlation of AGEs with diabetic gastrointestinal motility disorders is seldom reported. In this review article,the roles and possible mechanisms of AGEs in diabetic gastrointestinal motility were summarized.

Objective:To improve the work of drug quality sampling and testing. Methods:The regulation of testing related work in Drug Quality Sampling and Testing Regulation was analyzed and discussed. Results and Conclusion: Some suggestions were pro-vided in order to improve the regulation of testing work in Drug Quality Sampling and Testing Regulation.

At present,there are many problems in the cultivation for medical students including lack of humanistic education,insufficient healthy personality shaping and innovation education.We made explorations in aspects of updating education concept,enhancing faculty construction,emphasizing basic course teaching and promoting students' abilities so as to cultivate the comprehensive quality of students majored in medical imaging (ultrasonic medicine).

[Objective]To investigate effect of PBL-Seminar teaching method in pharmacy.[Methods] Take 40 masters of pharmacy major from Zhejiang Chinese Medicine University, and 20 of them as test group(with PBL-Seminar teaching method) and others as control group(with traditional teaching method).With advanced pharmaceutics as an example, final y using the questionnaire to evaluate the teaching effect of the course. [Results] Compared with the control group, the test group shows increase significantly in cognitive depth of the major, learning initiative, awareness of the team, satisfaction of the teaching atmosphere. [Conclusion] The PBL-Seminar teaching method is innovative and effective, which effectively improves the students' initiatives and cognitive ability, and helps students to adapt to society.

Effective strategies to sterilize and disinfect the surface of sickbed should be adopted before the sickbed is moved into or out of an operation room.Ozone produced by Nano technology is used as disinfector.The experiments shows that the killing logarithm value to kill nature bacteria is between 0.54 and0.85 in short time.The effect of sterilization and disinfection for the surface of sickbed is satisfying without secondary pollution,so the new method can be used to sterilize and disinfect sickbed.

A 2 L tubular photobioreactor (PBR) was designed, and hydrogen production by Rhodospirillum rubrum uptake hydrogenase deficient mutant in this PBR under artificial illumination condition (including continuous illumination and light/dark cycle condition) and natural day/night cycle was investigated, respectively. Hydrogen production by R. rubrum uptake hydrogenase deficient mutant under artificial illumination lasts five days, and hydrogen yield under continuous illumination and light/dark cycle (12 h:12 h) reaches 5752 mL/PBR ? 158 mL/PBR and 5012 mL/PBR ? 202 mL/PBR, respectively. Under natural day/night cycle, hydrogen production lasts 6~10 days and the maximal hydrogen yield of R. rubrum reaches 2800 mL/PBR with the optimal light intensity of about 30000~40000 Lux. Hydrogen production under natural day/night cycle condition was lower than that under artificial illumination, however, it would be a promising technology of hydrogen production due to low cost and ease of operation of hydrogen production system.

The article introduced and stressed laryngeal mask airway(LMA)'s invention and development,structure and classification,history and current situation of the applications of LMA in neonatal resuscitation,placement methods,recommendation of international guidelines for neonatal resuscitation on LMA,advantage and disadvantage when LMA versus bag-mask and endotracheal intubation ventilation for neonatal resuscitation,LMA extensions of research in neonate,and significance and prospects of its application in China.

Objective To understand self-harmonious state of medical college students at present,and explore the relationship between self-harmonious and social avoidance and distress(SAD).Methods 412 medical college students were assessed by self-consistency and congruence survey(SCCS),social avoidance and distal scores were 92.06±12.80).The self-harmonious of medical college students have differences in the grade.sex,one-child and area;and the difierences have not reached the remarkable level of statistics(P＞0.05),but the difference of self-rigidity between male students and female students(male:19.35±4.20;female:17.73±0.372,-0.152).Conclusion The self-harmonious level of medical college students Was low.And the bad SCCS state will lead to social avoidance or anxiety.

Autophagy is a physiological process which delivers the mutant cytoplasmic proteins and dysfunctional subcellular organs into lysosomes for degradation to generate fuel in the deficiency conditions. It is mainly classified into macroautophagy, microautophagy and chaperon-mediated autophagy (CMA), as well as the selective autophagy such as mitophagy and aggrephagy. This review mainly introduces the key molecular markers of macroautophagy, CMA and mitophagy.
Autophagy ; Humans ; Lysosomes ; Mitochondrial Degradation ; Molecular Chaperones