Objective To explore the effect of repetitive transcranial magnetic stimulation (rTMS) on motor function in cerebral palsy children with epilepsy. Methods 270 cerebral palsy children with epilepsy hospitalized from February, 2011 to September, 2014 were ran-domized to control group (n=130) and treatment group (n=140). The control group received comprehensive rehabilitation, including mas-sage, exercise, occupational therapy, physiotherapy, speech training, cognitive function training and medication, and the treatment group re-ceived rTMS in addition. They were assessed with Gross Motor Function Measure-88 (GMFM-88) and Peabody Developmental Measure Scale-Gross Motor (PDMS-GM) before, and 1 and 2 months after treatment. Results The total scores of GMFM-88 and PDMS-GM in-creased more in the treatment group than in the control group (F>93.9, P<0.001). Conclusion rTMS can further improve the motor function in cerebral palsy children with epilepsy.

An innovative approach,named associating liver partition and portal vein ligation for staged hepatectomy (ALPPS),has made possible a marked increase in future liver remnant (FLR) over a short period of time,and has challenged the concept of unresectability.To date,ALPPS has been employed for a variety of primary and metastatic liver tumors from many centers across the world.Many technical variations of ALPPS have been described.However,much controversy has surrounded this procedure,and many problems remain to be solved,such as the reasons for rapid hypertrophy,the technical feasibility,safety and long-term oncologic outcomes,and the result compared with the conventional two-stage hepatectomy.These aspects are needed to be evaluated further in large-scale studies.We believe that the ALPPS procedure will has much room for further development.

Endoscopy ; methods ; Humans ; Neck ; surgery

p53,the widely studied tumor suppressor gene ,plays a key role in regulating cell cycle ,repai-ring DNA damages , eliminating free radicals and regulating immune responses and so on .The recent studies showed that p53 mutation was in close biological connections with the occurrence , development , infiltration and metastasis in over 50 percent digestive systemic malignant tumors .In view of the current researches ,we review the biological features of p53,the relationship between p53 and digestive systemic malignant tumors ,and gene therapy of p53 to provide references for the pathogenesis ,diagnosis,treatment and prognosis of digestive systemic malig-nant tumors in this paper .

Antineoplastic Combined Chemotherapy Protocols ; therapeutic use ; Camptothecin ; administration & dosage ; analogs & derivatives ; Chemotherapy, Adjuvant ; Colorectal Neoplasms ; drug therapy ; pathology ; surgery ; Disease-Free Survival ; Fluorouracil ; administration & dosage ; Humans ; Leucovorin ; administration & dosage ; Postoperative Care ; Treatment Outcome

OBJECTIVE:To probe the advantages and disadvantges of soft packing container of hospital－ prepared infusion fluid.METHODS:The hospital－ prepared bottled infusion fluid was compared with soft parking fluid in respect to production costs,quality of preparation and clinical use.RESULTS ＆ CONCLUSION:The soft packing infusion fluid has developing potential,however,at present there exist some problems to be settled.It can not take the place of bottled infusion fluid in the near future.

Guinea pig, pigeon and toad are the vertebrates on different evolution level. The acid phosphatase content in the hepatocytes of centrilobular area and periportal area of hepatic lobules were quantitatively measured by microspectrophotometer and image analyser. The results showed that the content of acid phosphatase of hepatocytes was highest in guinea pig, lowest in pigeon, and toad in between the both. The average density of acid phosphatase distribution in the hepatocytes increases according to the evolution order. The significance of this phenomenon was discussed.

【Objective】To establish a simple,rapid and practical method for the in-vitro isolation,purification and proliferation of rat marrow mesenchymal stem cells(MSCs).【Methods】Rat MSCs were isolated and purified by differential adhesion method.The effects of conditioned medium on the morphologic characteristics and growth of rat MSCs were observed.【Results】Rat MSCs were effectively purified by differential adhesion method,and grew well with good proliferation and normal morphology in conditioned medium.【Conclusion】Differential adhesion method and conditioned medium are effective for the purification and culture of rat MSCs.

0.05). Conclusion The method is simple,accurate,reliable,less-reagent used and little inference of other metal ions. It is suitable for rapid determination of lead in the fresh marine products.

Objective To study and to improve the understanding of the etiology, diagnosis and treatment of familial congenital adrenal hyperplasia(CAH) due to 17? hydroxylase deficiency. Methods 2 rare cases of 17? hydroxylase deficiency in a family were studied with review of the literature. Results 2 cases were definitely diagnosed,one being male pseudohermaphroditism and the other female hypogonadism.Treatment consisted of replacement doses of glucocorticoid hormones and supplemented by estrogen therapy.The serum potassium became normal and the blood pressure was kept below 150/90 mm Hg. Conclusions 17? hydroxylase dificiency is a kind of hypertensive forms of CAH and is inherited as an autosomal recessive trait,its prevalence being rare.It is associated with hypogonadism or pseudohermaphroditism, hypertension or hypokalemia and with absent/decreased 17 OHCS and 17 KS.Hypoaldosteronism and positive dexamathasone inhibition test are the outstanding features.