ObjectiveTo observe the clinical efficacy of microinvasive thread embedding plusShe Gan Ma Huangdecoction based on ordinary Western medications in treating chronic obstructive pulmonary disease (COPD) (cold-phlegm obstructing the lung). MethodThe treatment group was intervened by microinvasive thread embedding plusShe Gan Ma Huangdecoction based on ordinary Western medications, while the control group was by the Western medications alone.ResultThe markedly effective rate and total effective rate were respectively 10.0% and 93.3% in the treatment group;the pulmonary function showed significant improvements in both groups.ConclusionMicroinvasive thread embedding plusShe Gan Ma Huangdecoction based on Western medications can produce a more significant therapeutic efficacy than dry Western medicationsin treating COPD (cold-phlegm obstructing the lung) in acute attack stage, and it can simultaneously improve the pulmonary function.

Increased research and exploitation of the low-temperature enzymes of antarctic microorganisms have occurred over recent years. There are a lot of study on protease, lipase and amylase, and so on. In antarctic microorganisms while some peculiar enzymes of antarctic microorganisms are still less researched. The recent development of the peculiar enzymes of the antarctic microorganisms was reviewed in this article. The properties of chitinase, dehydrogenas,?-galactosidase,RNA polymerase,DEAD-box RNA Helicase and metalloprotease etc. were introduced in detail, and the prospects of their application were also discussed.

Colorectal cancer (CRC) is one of the most common digestive system neoplasms in China. Recently, the morbidity and mortality rates of CRC continue to increase with the improvement of people's living standard and the change of the dietary structure. It was accepted that the etiology of colorectal cancer is a multi-factor and multi-step process. However, the mechanism of CRC is still unclear. MicroRNAs (miRNAs) are a class of -21 nucleotide non-coding RNAs and function as a negative regulator of gene expression after transcription, participating in tumor angiogenesis, tumor cell proliferation and invasion. MicroRNA-21 (miR-21), as an important oncogenic RNA, plays a vital role in the development and progression of CRC. This review summarizes the advances in research on miR-21 in colorectal cancer.

In order to improve the performance of the photorefraction device,shorten the detection time and improve the accuracy of measuring,the theory of a new kind of double-cranny eccentric photorefraction device is described.Some features and key point of technology are emphatically pointed out.A method is put forward to determine the ocular diopter by image processing.

Objective To observe the therapeutic effect of therapy of nourishing liver and activating blood for the treatment of multiple sclerosis(MS) with peripheral neuropathy(PN).Methods Twenty-six MS with PN patients admitted in out-patients department were enrolled into the study.The patients were given herbal medicine with the actions of nourishing liver and activating blood on the basis of routine western medicine.The relief of symptoms and signs of PN,score of nervous function evaluated by Expanded Disability Status Scale(EDSS),electromyogram(EMG) were examined before treatment and one year after treatment.Results One year after treatment,symptoms and signs of PN were relieved,EDSS score was decreased,the latency of motor nerve and sensory nerve was shortened and conduction velocity was increased,and incidence of wave F was increased and its latency was shortened(P

Objective To investigate the epidemiology and drug resistance associated with fungal infection during early postoperative period after liver transplantation in the purpose of prevention and treatment.Methods A total of 118 cases of liver transplantation admitted from April 2004 to January 2009 in Nanfang Hospital were studied retrospectively,and the fungal infection and drug resistance were identified.Results Fungal infections occurred in 26 cases (22.0%).Totally there were 49 fungi strains isolated,of which mainly Candida albicans (57.1%),followed by Aspergillus (18.4%),Smooth Candida (10.2%),Candida tropicalis (6.1%),Candida parapsilosis (4.1%),and Candida krusei (4.1%).The sensitive rate of voriconazole,itraconazole,amphotericin B,5-fluorouracil,fluconazole were 92.0%,90.0%,75.5%,73.5%,and 55.1% respectively.Conclusion Because of the change of fungi strains and the increase of drug resistance,it’s important to identify the fungi and drug resistance for the purpose of prophylaxis and treatments.

OBJECTIVE: There are some people in population susceptible to acute mountain sickness. Therefore, it is important to analyse, assess and integrate certain research results to build prediction system and mathematics model in order to predict those susceptible people when army goes to tableland.DATA SOURCES: Computer was used to search databases such as Medline, PubMed and PML to find articles regarding prediction of people susceptible to acute mountain sickness from January 1970 to December 2002 with the search words "acute mountain sickness, susceptible population,prediction" . The language was limited to English. At the same time, Chinese Journal Full-text Database, Chinainfo and CBMdisc were searched to find articles from January 1970 to August 2004 by the Chinese language of "acute mountain sickness, susceptible population and prediction". The research targets are susceptible people to acute mountain sickness. At last,trace-back method was used to supplement some literature and monographs.DATA SELECTION: After systematically analyzed and concluded the literature information and screened researches without conducting experiment, full text of the rest literature was searched and used as selective criteria if it could be used as prediction indicator of susceptible people to acute mountain sickness.DATA EXTRACTION: Totally there were 19 prediction indicators generalized. After conducting systemic analysis, Delphi method and analytic hierarchy process(AHP) to the indicators, 13 were selected while the other 6 were excluded.DATA SYNTHESIS: The indicators were classified according to nervous-humoral regulation ability, oxygen capture ability of respiratory system,anti-anoxia ability of central nervous system, mental health and health service ability. Based on these, system analysis, Delphi method and AHP method were used to screen prediction indicators, establish indictor system, confirm the weighted indicators and weighted indicator system as well as standardize the prediction indicators.CONCLUSION: According to the principle of prediction model and model methods, weighted linear synthesis method was used to build the predictive mathematic model. The project of susceptible population prediction of acute mountain sickness in army when entering tableland urgently was proposed combining the health service ability of army.

Spinal cord injury(SCI) is a serious nervous system trauma,which may consequently lead to various degrees of paralysis and toilet obstacles,and its disability and the high cost heavily burdened the families and community.Therefore,the research on spinal cord tissue regeneration and the repair after injury has important practical significance.A large number of experimental studies have shown that neurotrophic factor plays an important role in the nerve tissue repair process.This article reviews new research progress about the effects of neurotrophic factor in this field.

Bladder cancer is a common tumor with a high rate of recurrence and quick progression.Many biomarkers for the detection of bladder cancer have been identified,but none has been reported to date to have sufficient sensitivity and specificity.Recent researches are concentrated on p53,Rb,Cyclin D,P27kip-1,FGFR3,Cadherin,Survivin,Aurora,MMP,VEGF and DNA Methylation.In spite of their different sensitivities for bladder cancer of different stages or degrees,these biomarkers are valuable for its diagnosis and prognosis.

OBJECTIVE To study the phenomenon of hepatitis B surface antigen(HBsAg) and antibody(HBsAb) both positive in blood samples.METHODS Using electro-chemo-luminescence immune system E170 to detect HBsAg and HBsAb in clinical samples and retest the both positive cases by another two reagents for HBsAg and another three reagents for HBsAb.RESULTS All 7332 samples showed 140 both HBsAg and HBsAb positive(1.9%) and 73 of them were retested for HBsAb by another three reagents which gave altogether 24 positive results,which was not related to each other.Those gave higher HBsAb value by E170 showed higher positive rate by Abbott reagent.CONCLUSIONS HBsAg and HBsAb both positive results are not rare.It may be due to the interactions between the patient and the infected hepatitis B virus.Besides,the quality of reagents and correct lab operating procedures may also affect the test results.