3.Spatial Direction Judgements Based on Integrating of Spatial References
Space Medicine & Medical Engineering 2006;0(05):-
Objective To investigate how target position and observer's heading affect spatial direction judgement (object locating judgement vs. orienting judgement). Methods Based on visual spatial scene and spatial memory, localization judgement and orientation judgement were used as tasks in four subjects-within experiments respectively. The data of response time were collected as the main dependent variables, and the total, 80 subjects (40 female), participated in the study. Results 1) 0? (front) and 180? (back) advantage effect, north advantage effect (expect for Exp.3), and cardinal direction-R90? position advantage effect were significant; 2) There was no significant difference on response time between Exp.1 and 2, and between Exp.3 and 4; no significant difference on time used for location was found between Exp.3 and 4, but each of them was longer than its corresponding response time for judgement task. Conclusion The effect modes of heading and target position are all consistent between the two types of spatial direction judgements, and the effect modes will not be changed according to differences in information medium and processing.
4.Effect of Angelicae Sinensis Decoction for Supplementing Blood on mesangium cell proliferation,TGF-?_1 mRNA and NF-?B under high glucose
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(06):-
Objective:To investigate the effect of Angelicae Sinensis Decoction for Supplementing Blood on mesangium cell proliferation,TGF-?1 mRNA and NF-?B under high glucose. Methods:①Thiazole blue (MTT) colorimetric method was used to observe the dynamic state of mesangium cell proliferation in various treatment factors; ② Fluorescent quantitation polymerase chain reaction (Real time-PCR) was used to detect the expression of transforming growth factor beta 1 mRNA in mesangium cells under various treatment factors; ③Western-blot was used to detect the expression of nuclear factor-kappa B in mesangium cells under various treatment factors. Results:In vitro cultured mesangium cells obviously proliferated under the stimulation of high glucose; the expression of TGF-?1 mRNA and NF-?B in mesangium cells increased (P
5.Treating cardiovascular disease in peri-menopausal period by theory of yin deficiency,blood stasis,heat-toxin
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(06):-
Cardiovascular disease in peri-menopausal period is a kind of climacteric syndrome which based on the symptoms of the cardiovascular system as the main manifestations. It is manifested as hypertension,pseudo-angina,arrhythmia. Hormone replacement therapy or symptomatic treatment is the common used method of modern medicine,although a certain degree of efficacy,but there are also significant disadvantages. In the treatment of cardiovascular disease in peri-menopausal period,TCM has certain advantages. In this paper,we treat cardiovascular disease in peri-menopausal period from the theory of 'yin deficiency,blood stasis,heat-toxin'and propose the method of 'nourishing yin,promoting blood circulation and detoxification'.
6.How to scientifically set up an index system to comprehensively assess clinical medical undergraduates?
Chinese Journal of Medical Education Research 2013;(3):250-253
There are still two outstanding problems in comprehensive quality assessment index system of clinical medical undergraduates:contents of assessment is incomprehensive and every index has no quantitative research based weight.This article elaborated on a complete index framework,covering required knowledge,abilities,attitude,morality of clinical medical undergraduates and proposed a set of methods and processes,including literature research method,system analysis method,brainstorming,expert interviews,Delphi method,and some statistical methods,providing a theoretical basis for the development of comprehensive quality assessment index system for clinical medical undergraduates.
7.Clinical effect and safety of different concentrations of atropine preparations in the treatment of ametropia
Chinese Journal of Biochemical Pharmaceutics 2016;36(11):106-108,111
Objective To investigate the effect and safety of Atropine preparations of 0.1%and 0.01%concentrations in the treatment of Ametropia.Methods 123 cases of ametropia from April 2014 to August 2015 in ophthalmic hospital of ningbo were randomly selected and divided into three groups, 41 cases in each group.High concentration group received 0.1%atropine sulfate eye drops treatment,low concentration group received 0.01%atropine sulfate eye drops treatment,and the control group received artificial tear mytear,and three groups were treated for one year.Changes in vision, refraction, intraocular pressure and axial length of the eye were compared after the treatment.Results High concentration group >low concentration group >control group in the the difference of distant visual acuity before and after the treatment ( P<0.05 ) , control group >low concentration group>high concentration group in the refractive index,intraocular pressure and ocular axis length difference before and after treatment (P<0.05),and the effective rate in the low concentration group 85.37%and high concentration group 90.24%had no significant difference.Adverse effects rate in high concentration group was 21.95%which was higher than low concentration group 4.88%(P<0.05).Conclusion 0.1%and 0.01%concentrations of atropine were effective control of Ametropia in flexion and axial length spectrophotometry, and then improve the visual acuity, and the former is better,but the 0.01%concentrations had higher safety.
9.The diagnosis value of magnetic resonance diffusion weighted imaging for breast cancer
Chinese Journal of Primary Medicine and Pharmacy 2012;19(14):2087-2089
Objective To explore the differential diagnosis value of DWI ADC for breast lumps,improve the diagnosis of breast cancer specificity.Methods 93 patients with 105 breast tumors were performed with routine MR series and DWI,and the ADC values were measured.Results Lesions ADC values:average ADC value 43 benign lesions in 37 cases was(1.37±0.36)×10-3 mm2/s,the different value between max and min was(0.63±0.19)×10 -3s/mm2.Average ADC value of 62 malignant lesions in 58 patients was(0.90±0.53) × 10 -3 mm2/s,the different value between max and min was(0.91±0.27)×10-3 mm2/s.By statistical analysis,both average ADC values and the max and the min ADC difference value were very significantly different(P<0.01).Draw diagnosis benign and malignant lesions ROC curves,with ADC values 0.11×10 -3 mm2/s for critical value to judge benign and malignant standard,sensitivity was 67%,specificity was 72%.With 1.0×10- 3 mm2/s for critical value,specificity can raise to 84%,and sensitivity came to 60%.With the maximum and minimum ADC difference value 0.75 × 10-3s/mm2 for critical value,sensitivity was 67%,specificity was 68%.If with 0.80 for critical value,sensitivity was 53% and specificity 82%.Conclusion The average ADC values of DWI were significant for the identification of benign and malignant lesions.
10.Carotid artery stenosis and cognitive impairment
International Journal of Cerebrovascular Diseases 2012;20(2):147-151
The relationship between carotid artery stenosis and cognitive function are receiving increasing attention.Most studies have shown that carotid artery stenosis has a direct impact on cognitive impairment.Carotid endarterectomy or stenting can improve the cognitive function to varying degrees in patients with carotid artery stenosis.The mechanism of cognitive impairment in patients with carotid artery disease may be associated with hypoperfusion,white matter lesions,multiple lacunar infarction and spontaneous emboli.