Child ; Diabetes Mellitus, Type 1 ; complications ; Humans ; Male ; Nephrosis, Lipoid ; complications

OBJECTIVE: To evaluate the sustained efficacy of 2-year sublingual immunotherapy (SLIT) and 1 year after 2-year SLIT in children with allergic rhinitis (AR). METHOD: This study is a randomized, open and prospective trial. One hundred twenty children (between 4 and 11 years old) suffering from AR duo to mite were chosen from November, 2008 to June, 2009 in department of otolaryngology in our hospital divided into two groups: 60 underwent 2-year course of SLIT and one year follow-up combined with 3-year drug therapy as SLIT group; 60 received only drug therapy as control group. The patients were evaluated at three time points (baseline, end of SLIT and 1 year after SLIT discontinuation) regarding symptom scores including total nasal symptom score (TNSS), sneezing, rhinorrhoea, nasal obstruction, nasal itching and total medication scores (TMS) and adverse reaction. RESULT: (1) At the end of SLIT, the symptom scores excepting sneezing and total medication scores in SLIT group are obviously lower than those in control group (P < 0.01). At 1 year after SLIT discontinuation, all of the score including sneezing (P < 0.05) in SLIT group are lower than those of control group. (2) At the end of SLIT and 1 year after SLIT discontinuation, all of the scores are lower than those at baseline in SLIT group (P < 0.01); the scores were no different in SLIT group between the end of SLIT and 1 year after SLIT discontinuation (P > 0.05). But at the end of SLIT and 1 year after SLIT discontinuation, TMS was higher than it at baseline in control group (P < 0.01). At 1 year after SLIT discontinuation, nasal obstruction score was higher than it at baseline (P < 0.05). CONCLUSION SLIT can obviously improve the AR and the efficacy can sustain after 1-year SLIT discontinua tion. Drug increased in 3 years without SLIT.
Child ; Child, Preschool ; Female ; Follow-Up Studies ; Humans ; Male ; Prospective Studies ; Rhinitis, Allergic ; therapy ; Sublingual Immunotherapy ; Treatment Outcome

Anemia, Aplastic ; drug therapy ; Drugs, Chinese Herbal ; therapeutic use ; Humans ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive ; drug therapy ; Medicine, Chinese Traditional ; Phytotherapy

ObjectiveTo compare the therapeutic efficacies of pricking Sifeng (EX-UE10), spine pinching, and the combination of pricking Sifeng and spine pinching in treating infantile dyspepsia.MethodBy simple randomization, ninety-six patients were divided into a pricking group (n=32), a spine pinching group (n=32), and a combination group (n=32). One-month treatment was considered as a course. Before treatment and after 1 treatment course, the 3 groups were evaluated by symptom scale and the criteria of symptom and therapeutic efficacy of traditional Chinese medicine to determine the therapeutic efficacy. ResultThe total symptom score decreased significantly in the three groups after treatment (P<0.01), indicating that the three treatment protocols were all effective; according to the paired comparison of the post-treatment total symptom score by using Chi-square test, the score of the combination group was significantly lower than that of the other two groups (P<0.05). The improvement of body weight and height was statistically insignificant in the three groups (P>0.05); while the improvements of appetite, vitality, sleep, hyperidrosis, infection, irregular defecation, abdominal bloating, and hairglossiness were statistically significant in the three groups (P<0.01). The recovery and markedly-effective rate was 51.6% in the pricking group, 48.4% in the spine pinching group, and 77.4% in the combination group; the therapeutic efficacy of the combination group was significantly higher than that of the other two groups (P<0.05).ConclusionThe three treatment protocols, i.e. pricking Sifeng, spine pinching, and the combination of the two methods, all can effectively improve the symptoms of infantiledyspepsia, while the therapeutic efficacy of the combination protocol is superior to the two methods usedseparately.

The article summarizes the questions of clinical practicing in obstetrics and gynecology through clinical teaching in person,and find out some measures to improve teaching quality of clinical practicing.

Child, Preschool ; Coronary Aneurysm ; etiology ; therapy ; Humans ; Infant ; Male ; Mucocutaneous Lymph Node Syndrome ; complications ; therapy ; Thrombosis ; complications ; therapy ; Urokinase-Type Plasminogen Activator ; therapeutic use

Objective To compare the sclerotherapic effects of different concentrations of lauromacrogol on endometrial cyst models in rats in two ways :10 minutes retention with extraction and retention without extraction .Methods Ninety SD rats after modeling were randomly divided into three groups :group A ,10 minutes retention with extraction;group B ,retention without extraction;group C , normal saline .While both A and B group were randomly divided into four subgroups with different concentrations :1% ,0 5.% ,0 2.5% ,and 0 1.25% . Seven days after treatment the cure rates and histopathological changes were observed .Results Cure rates in group A were 86 7.% ,71 4.% ,50% and 20% ;in group B were 100% ,100% ,87 5.% and 37 5.% .In both A and B groups ,the cure rates were not significantly different between 1% ,0 5.% and 0 2.5% concentration subgroups ( P >0 0.5) ,the cure rates of these subgroups in group B had statistical significance with 0 1.25% concentration subgroups and the saline control group( P <0 0.5) ,but there were no significant difference between 0 2.5% and 0 1.25% concentration subgroups in group A .Compared the differences of the cure rates among the same concentration subgroups , it had no statistical significance in groups A and B of 1% and 0 1.25% concentration subgroups( P >0 0.5) , but between 0 5.% and 0 2.5% concentration subgroups ,it had statistical significance( P <0 0.5) .Conclusions It will be conductive to enhancing the sclerotherapic effect if the lauromacrogol concentration remains above 0 2.5% and does not be extracted from the cyst models .

Objective To study the improvement of sleep and life quality in chronic insomina patients with abdominal acupuncture. Methods Ninety patients were randomly divided into study group and control group. The study group were treated with abdominal acupuncture combined with hypnotics, and control group of with pure hypnotics. Ten treatments formed a course. The therapeutical effect was assessed with Pittsburgh Sleep Quality Index (PSQI) and Questionnaire SF-36 before and after treatment and 2 weeks after treatment respectively. Results The significant improvement was obtained in aspects of general effective rate right after the treatment, general score of PSQI and score of Questionnaire SF-36, and very significant improvement two weeks after the treatment not only in PSQI scores in sleep quality, sleep efficiency, daytime function and hypnotics but in SF-36 score. Conclusions Abdominal acupuncture can treat chronic insomnia through regulating body environment so as to improve sleep and life quality, and eliminate the hypnotic side effects.

Objective To investigar evaluate the value of anti-radiation with X-ray protective equipment for radiological interven-tion operation personnel.Methods Surveyed 60 cases of these operation staff during interventional operation in our hospital from October,2011 to October,2012,divided into the research group and the control group according to the physician protective habits, the research group was comprehensive protection with protective equipment including lead underwear,lead glass shield,lead cloth-ing,lead collar,lead the mask glasses radiation dose,the control group was partial protection with only employ lead clothes,lead col-lar,two groups were similar interventional operation on the same X-ray vessel machine,analysed the radiation dose of inside and outside the protective clothing changes and the blood picture for 2 groups personnel.Results The study group received radiation dose was significantly lower than the control group,the difference was statistically significant(P<0.01).Radiation dose has obvi-ous difference inside and outside the protective clothing,the difference of two groups were significant(P<0.01).The blood picture of research group was reduced lower than the control group,but had no significant difference(P>0.05).Conclusion The anti-radi-ation effect of X-ray protection equipment is remarkable for intervention operation personnel,should advocate the comprehensive personal radiation protection in the intervention operation period for the relative professionals persons.

Twenty-eight cases of Infantile Tourette's syndrome were treated by puncturing Back-Shu points. In 28 cases of the patients, the results showed cure in 6 cases, effect in 21 cases and failure in one case, and the total effective rate in 96.4%.