1.The survey of the multidrug-resistant bacteria infection in paediatrics of our hospital
Zhongyou TAN ; Ouyang CHEN ; Yangfan HE
Chinese Journal of Primary Medicine and Pharmacy 2012;19(17):2588-2589
Objective To investigate the multidrug-resistant bacteria infection in pediatrics of our hospital and guide the rational usage of antibiotic,Methods The retrospective survey method was adopted to analyze the multidrug-resistant bacteria infection of 591 patients in paediatrics from 2009 to 2011.Results There were no statistical differences of multidrug resistance bacteria infection rates in the three years (x2 =0.028,P =0.986).Among 591 patients,17 patients were with multidrug-resistant bacteria infection,the positive rate was 2.87%,82.4% origin of society area,64.7% was respiratory tract infection,58.8% resistance bacteria including Klebsiella pneumoniae and Escherichia coli,appear multidrug resistance bacteria infection previous all used antibiotic drugs.Conclusion The multidrug resistance bacteria infection is related to occur in paediatrics abuse and unrationaly use of antibiotics.Its should be strengthened to supervise and manage.
2.Effects of high-frequency jet ventilation on oxidative stress in patients during one lung ventilation
Zhiqing YIN ; Zhongyou HE ; Zhenfei YUAN ; Beibei WANG ; Ruifeng QIAN ; Yanhong WANG
Chinese Journal of Postgraduates of Medicine 2011;34(15):18-20
Objective To determine the effects of high-frequency jet ventilation (HFJV) on oxidative stress in patients during one-lung ventilation (OLV). Methods Forty-five patients undergoing elective radical esophageal cancer resection were divided into three groups with 15 cases each by random digits table: two lung ventilation group ( group A), OLV group (group B), HFJV- OLV group ( group C, working pressure 1 kg/cm2 and frequency 100 times/min). Venous blood samples were taken before induction (T0),at30min (T1),90min (T2),150min (T3) after OLV and the end of operation (T4) for measuring serum superoxide dismutase(SOD),malondialdehyde (MDA) and nitric oxide (NO). Results SOD was lower at T2-T4 in group B[(47 ± 10), (37 ±9), (41 ±7) kU/L] and group C[(58 ± 12), (51 ± 11), (49 ± 9) kU/L] than those in group A [(78 ±8), (75 ±7), (79 ±6) kU/L](P< 0.05),and MDA and NO were lower at T1-T4 in group B and group C than that in group A(P< 0.05). SOD was higher at T3 in group C than that in group B (P < 0.05), MDA at T1-T4 and NO at T2-T4 were lower in group C than those in group B (P < 0.05). Conclusion HFJV can effectively decrease oxidative stress in patients during OLV.
3.Analysis the causes of endplate injury in oblique lateral interbody fusion
Zhongyou ZENG ; Xiangqian FANG ; Weihu MA ; Dengwei HE ; Wenfei NI ; Wei YU ; Xin ZHAO ; Yongxin SONG ; Jianqiao ZHANG ; Shiyang FAN ; Fei PEI ; Sunwu FAN
Chinese Journal of Orthopaedics 2020;40(17):1144-1154
Objective:To investigate the characteristics and causes of endplate injury in the oblique lateral interbody fusion for the treatment of lumbar diseases, and summarize the precaution of endplate injury.Methods:Thirty-five cases of endplate injury were observed, which were originally treated with oblique lateral interbody fusion with or without pedicle screw fixation from October 2014 to December 2017. There were 7 males and 28 females, and the age ranged from 51 to 78 years old (averagely 62.8±8.13 years). There were 2 cases of lumbar disc degeneration, 10 cases of lumbar canal stenosis, 17 cases of lumbar degenerative spondylolisthesis, 2 cases of lumbar spondylolysis with or without spondylolisthesis, and 4 cases of lumbar degenerative scoliosis. Lesion sites contained L 3,4 in 2 cases, L 4,5 in 21 cases, L 2-4 in 3 cases, L 3-5 in 4 cases, L 2-5 in 3 cases and L 1-5 in 2 cases. Preoperative bone mineral density examination revealed there were 7 cases of T>-1 SD, 24 cases of -2.5 SD