This study was aimed to explore the clinical efficacy and differences in hemorheological parameters in sudden deafness treated with Chinese medicine combined with electric acupuncture and western medicine . Patients were selected according to the diagnostic criteria of sudden deafness. Patients were randomly divided into the Chinese medicine combined with electric acupuncture group ( 35 cases ) and the western medicine group (30 cases). In the treatment group, Tongqiao Huoxue Decoction was orally administrated in combination with electric acupuncture on Jiaj i points on the neck region . In the western medicine group , alprostadil and prednisone were used . For both groups , 10 days were one treatment course . The results showed that after two treatment courses , the hearing improvement of two groups was compared . The total efficiency of Chinese medicine combined with electric acupuncture group was 91 . 4%. And the total efficiency of the western medicine group was 66 . 7%. There were significant differences between two groups ( P < 0 . 05 ) . The treatment efficiency of tinnitus between two groups was also compared . The total efficiency of Chinese medicine combined with electric acupuncture group was 91 . 2%. And the total efficiency of the western medicine group was 78 . 6%. There was no significant difference between two groups . The comparison of dizziness relieving effect between two groups showed that the total efficiency of Chinese medicine combined with electric acupuncture group was 94 . 1%; and the total efficiency of the western medicine group was 73 . 3%. There was no significant difference between two groups . The hemorheological parameters were also improved . In the Chinese medicine combined with electric acupuncture group , indexes such as blood viscosity ratio , plasma viscosity ratio , erythro-cyte electrophoresis time and hematocrit were all improved obviously compared to western medicine group . There was significant difference between two groups ( P < 0 . 05 ) . It was concluded that in the improvement of clinical symptoms of sudden deafness, physical signs and hemorheology, Chinese medicine combined with elec-tric acupuncture receives better effects compared to western medicine .

AIM: To observe the therapeutic effect of Meituokang(Floium Ginkgo Extract and Tertram Ethypyrazine injection) combined with western medicine in treating patients with angina pectoris. METHODS: 74 patients with angina pectoris were randomly divided into two groups,the control group(38 cases) were only treated with the routine Isosorbide Mononitrate; Metoprolol;Amlodipine;Aspirin enteric coated tablets and the treatment group(36 cases) were treated with Meituokang Injection qd,iv gtt besides the conventional treatment method of the control group.The course lasted 14 days. RESULTS: In comparison,the total efficacy rate of angina pectoris and the electrocardiogram(ECG) were 94.44% and 80.56% in the treatment group and 76.32% and 52.63% in the control group,respectively.There was significant difference between two groups by statistical analysis(P

Objective: To study the super high-dose chemotherapy in drug-resistance Ⅲ B osteasarcoma with autologous bone marrow transplantation. Methods: The chemotherapy was carried out in 4 patients with drug-resistance Ⅲ B osteosarcoma. The autologous bone marrow was harvested before chemotherapy and reinfused after chemotherapy when the serum concentration of methotrexate reduced to 1.0?10~(-7) mol/L. The chemotherapy included ,methotrexate 500 mg/kg , adriamycin 25 - 75 mg/m~2 and vincristine 1.5 mg/m~2 with low dose citrovorum factor rescue. Results: Four patients tolerated the chemotherapy well and felt better than before. The pulmonary metastases had various degrees of reduction in 2 patient and calcified in 1 patient, but progressed in 1 patient. Conclusion: Super high-dose chemotherapy has good response in drug-resistance ⅢB osteosarcoma and is safe with autologous bone marrow transplantation. This regimen is worth to be further studied and be used in ⅡB osteosarcoma.

Objective To determine the applicability of locally continuo u s application of alendronate for the prevention of prosthesis aseptic loosening. Methods Using the method of in vitro cell culture to detect the influence of a lendronate with different concentrations(1?10－11mol/L,1?10－9mol/L,1?10－7mo l/L,1?10－6mol/L,1?10－5mol/L) on the proliferation, secretion and osteogenesi s of human osteoblasts as well as the effect of the motility, respiration, phago cytosis and bactericidal ability. Results Higher concentration of alendronate(1 ?10－6mol/L,1?10－5mol/L) improved local antiinfection ability, but inhibited osteogenesis (1?10－5mol/L). Lower concentration(1?10－11mol/L,1?10－9mol/L,1 ?10－7mol/L) inhibited the bactericidal effect of neutrophils, but stimulated o steogenesis(1?10－11mol/L,1?10－9mol/L). Conclusion Locally continuously usin g alendronate around prosthesis to prevent and treat aseptic loosening must be h andled with discretion. Its concentration should not be below 1?10－6mol/L in the early period after arthroplasty operation, but the concentration should be 1?10－11mol/L or 1?10－9mol/L in the late period.

Objective To investigate the effects of medullary reaming on respiratory and circulatory system in dog model during total hip replacement. Methods Twelve mongrels were randomly divided into two groups. In control group, femoral necks were cut while femoral canals were not disturbed. In experimental group, femoral canals were reamed with femoral rasps as done in total hip replacement. The changes of hemodynamics and pulmonary function were monitored during perioperative period. The postmortem pulmonary tissues were studied by pathological examination. Results No fat embolus was found in any lung sections of control group. Meanwhile, pulmonary fat emboli were found in all of experimental group. After fat embolism happened, cardiopulmonary effects included increased pulmonary artery pressure, pulmonary shunt and pulmonary vascular resistance accompanying a decrease in partial pressure of oxygen and cardiac output. There is statistically significant difference in response between the two groups. Conclusion The present study showed that embolic events and intraoperative pulmonary impairment are common during reaming of femoral medullary canal in total hip replacements. Further research can be made with this model in order to reduce the risk of fat embolism syndrome.

Objective To describe the effect of cannualted rasps in reduc in g the fat embolic risks during preparation for femoral canal in experimental tot al hip arthroplasty. Methods Twelve mongrels were used to perform resection of b ilateral femoral heads, and randomly assigned to one of two groups with six each . In experiment group, impacting cannulated rasp was used in preparing femoral c anal; while, in control group, impacting traditional rasp was used. Both the ras ps were of same shape; however, there was a 4 mm diameter canal inside the cannu lated rasp connecting its two ends. A bone hole was made through the lateral fem oral cortex to the femoral canal at a point 12 cm distal to the greater trochant er in order to measure the intramedullary pressure of femoral canal when the fem oral canal was prepared with either rasp. The pathology of the postmortem pulmon ary tissue was analyzed. Using quantitative morphometry, the size of fat embolus in the lung tissues and the volume proportion of lung tissues occluded by fat w ere measured respectively. The statistical differences between the two groups we re analyzed using t test. Results In control group, the intramedullary pressure during preparation of femoral canal with traditional rasp increased with a peak of (34.5?10.2)kPa, pulmonary fat emboli were found in all mongrels, the volum e proportion of postmortem lung tissue occluded by fat was 0.64%, and pulmonary arterial pressure increased to (2.2?0.4)kPa[the normal value was (0.8?0.3 )kPa]; while in the experiment group, the intramedullary pressure peak increas ed to (22.4?7.7)kPa, significantly lower than that of the control group; the volume proportion of lung tissue occluded by fat was 0.21% which was also signif icantly lower than that of the control group, and pulmonary arterial pressure wa s (1.7?0.4)kPa. The differences between the two groups were significant in al l measured values. Conclusion The present study suggests that conventional prepa ration of canal can cause an increase of intramedullary pressure, which may lead to pulmonary fat embolism and cardiopulmonary impairment. However, the cannulat ed rasp can decrease the volume proportion of lung tissue occluded by fat and al leviate the influence of preparation of canal on cardiopulmonary function.

Object iv e To observe the intermediate-term results of the H /G total hip arthroplast y.Methods Thirty-fivecases(40hips)with the H /G THA were reviewed with an average of 7.5years fol-low-up(range,6to10.2years).In th is grou p,the primary lesions of hip included avascular necrosis of femoral head(1 2hips,10cases),congenital dysplasia of hip(9hips,8cases),femoral ne ck fracture(8hips,8cases),osteoarthritis(4hips,4cases),reversion(3 hips,3cases)and ankylosing spondylitis(4hips,2cas-es).The clinical res ults were scored with Harris methods.The roentgenographic results were analyzed with Am stutz meth ods.Results Theclinical average Harris scores were95in3-year follow-up,89in5-year fol-low-up,83in7.5-year follow-up. Roentgenographic results of femoral components showed20hips with in-tra medu llary ossification,18hips with cortical hypertrophy around the distal prosthe ses,25hips with lo cal re-di olucent line,10hips with osteolysis in femu r calar and2hips with implants subsiding less than7mm.Roentgenographic resul ts of acetabular component revealed20hips with radi olucent line(8compo n ents with around radiolu cent,12components with local radiolucent ),7hips with osteolysis and1hip with polyethylene lining defluxion.Conclusion Theresul ts of clinical and roentgenographic performance in mid-dle-term is not as go od as that in short-term.The abnormal bone reaction is evidently higher in mid dle-term than in short-term.Though the above-mentioned manifestation is only restricted on the roentgenogram with-out clinic symptom,however,further fol low-up is need ed.It should be noted that one case had revi sion be-cause of the polyethylene lining defluxion resulted from clip loosening on the metal ace tabular com po nent ;although this seldom happens both at home and abroad,more attention should be paid to the revi sion case re-sulted from the mechanical m alfunction not from the prosthesis loosening.

OBJECTIVETo investigate the effect of cervical spine instability on sympathetic cervical spondylosis.

METHODSTwelve patients with cervical spondylosis showing sympathetic symptoms from 1992 to 2 000 were evaluated for cervical spine instability, immobilization of collar brace, MRI and surgical results.

RESULTSRadiologic evaluation cervical instability was observed radiologically in 7 of the 12 cases. Collar brace was obviously effective in 5 of the 12 cases and slightly effective in 7 cases. MRI showed abnormal signal for instability of the cervical spine in 7 cases. Surgery was markedly effective in 7 cases and moderately effective in 4 cases.

CONCLUSIONCervical spine instability was an important factor for sympathetic cervical spondylosis, which can be improved effectively by surgery.

Adult ; Aged ; Autonomic Nervous System Diseases ; etiology ; Cervical Vertebrae ; Female ; Humans ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Spinal Osteophytosis ; complications ; diagnosis ; surgery