1.Improve ment of Lunar DPX-L Dual Energy X-ray Absorptiometry Equipment
Bin YANG ; Zhongqing YUAN ; Mei ZHANG
Chinese Medical Equipment Journal 2009;30(7):71-72
Objective To solve the encountered problem of lack of space and dyskinesia of detector in dual energy X-ray absorptiometry system, Methods The method used PartitionMagic8.0 software to partition space in hard disk and added the load to keep the detector balance for moving, Results The original software can run in hard disk, and the pulleys are not gotten force from side. Conclusion The reason of problem is analyzed to find the method that can reduce the percentage for system failure and improve precision and accuracy of data.
2.Calculating the Consumed Peak Value of Oxygen in Central Oxygen Supply System Based on Poisson Distribution
Bin YANG ; Mei ZHANG ; Zhongqing YUAN
Chinese Medical Equipment Journal 2003;0(12):-
The objective of this paper is to find out a way that calculate the consumed peak value of oxygen in medical central oxygen supply system,which is the basis for discussion of purchasing hospital oxygen generating system.The author established a math model by poisson distribution to describe the consumed peak value of oxygen in medical central oxygen supply system to find out a convenience way to calculate the consumed peak value of oxygen.
3.Pressure-based Monitoring of Medical Central Compressing Air Supply System
Bin YANG ; Mei ZHANG ; Zhongqing YUAN
Chinese Medical Equipment Journal 1989;0(01):-
Objective To determine the indexes for evaluating medical central compressing air sypply system.Methods According to the gas equation,pressure calculation was perfomed with the pressure variation as the monitoring subject.Results Such parameters could be used for monitoring medical central compressing air supply system as as average velocity & instanteous velocity of gas consumption,air compressor's average exhaust velocity & exhaust velocity at start-stop point,and pressure-exhaust velocity curve of air compressor.Conclusion The method can be applied to enhancement of quality management & maintenance of the equipment.
4.Perioperative changes in serum levels of TNF-?,IL-6 and IL-10 in peri-operative period of liver orthotopic transplantation
Zhe YANG ; Zhongqing CHEN ; Xiaoqing JIANG
Medical Journal of Chinese People's Liberation Army 2001;0(09):-
Objective To study perioperative changes in serum levels of TNF-?, IL-6 and IL-10 in orthotopic liver transplantation without veno-venous bypass. Methods Sixteen patients with terminal liver disease underwent orthotopic liver transplantation under general anesthesia. Samples from arterial blood were obtained at beginning of surgery, before the anhepatic phase, 5min before recirculation, 15min and 60min after recirculation, 4h and 24h after operation, respectively. Serum levels of TNF-?, IL-6 and IL-10 were measured by ELISA. Results TNF-? and IL-6 concentrations were kept at a low level before operation, while IL-10 was not detected. The concentrations of IL-6 and IL-10 rose during the anhepatic phase (P
5.Comparison of Cyberwand dual probe lithotriptor and Swiss lithoclast master in ultrasonically guided percutaneous nephrolithotomy for renal staghorn calculi
Yang LI ; Feng ZENG ; Zhongqing YANG ; Hequn CHEN
Journal of Central South University(Medical Sciences) 2013;38(8):853-856
Objective:To evaluate and compare the effciency and safety of Cyberwand dual probe lithotriptor and Swiss lithoclast master in percutaneous nephrolithotomy for renal staghorn calculi.
Methods:A total of 138 patients with renal staghorn calculi were divided randomly into a Cyberwand dual probe lithotripter group (Group A, n=71) and a Swiss lithoclast master group(Group B, n=67). hTe data for operative time, blood loss volume, one-stage calculus clearance rate, hospitalization time, cost of hospitalization and complication in the two groups were collected and compared.
Results: The renal access was established successfully and the one-stage percutaneous nephrolithotomy (PCNL) was performed in the 2 groups. There was no significant difference in the size of stones, the age of patients and the complications between the 2 groups before the operations. Intraoperative gravel time in the Group A was signiifcantly shorter than that in the Group B (77.14±21.39 vs 84.25±20.62, P=0.049). There was no significant difference in the one-staged stone clearance rate, blood loss volume in the operation between the 2 groups. hTe one-staged stone clearance rate in the 2 groups were 67.6%(48/71) and 70.1%(47/67) respectively, with no signiifcant difference (P=0.854).
Conclusion:Two lithotrities were safe and effcient for renal staghorn calculi. But comparing with Swiss lithoclast master, Cyberwand dual probe lithotriptor is more effcient and convenient.
6.Preparation and in Vitro Release of Poly(lactide-co-glycolide) Microspheres Loaded with Ropivacaine
Xiaobao BI ; Zhongqing CHEN ; Li YANG ; Lesong HUANG
China Pharmacy 2005;0(13):-
OBJECTIVE: To optimize the preparation technology of poly(lactide-co-glycolide) (PLGA) microspheres loaded with ropivacaine (ROP-PLGA-MS) and study their powder particle characteristics and in vitro release characteristics. METHODS: ROP-PLGA-MS was prepared with PLGA as carriers using the water-in-oil-in-water(W/O/W) emulsion solvent evaporation method. The micromeritic characteristics of ROP-PLGA-MS,such as the particle size,loading and entrapment efficiency were taken as indexes for evaluation,and the preparation technology was optimized by orthogonal design. Its dissolution characteristics in vitro were studied. RESULTS: The prepared microspheres were spherical with smooth surfaces,with an average particle size of (2.525?0.047) ?m and over 80% falling in the range of 1.8~5.0 ?m. The encapsulation efficiency was (58.05?1.169)% and the drug loading efficiency was (6.067 ?0.312)%. The in vitro release curves of ropivacaine microspheres could be fitted with Higuchi equation. The accumulated release percentage of which was 82 % in 192 h,and t1/2=60.16 h. CONCLUSION: ROP-PLGA-MS has obvious sustained release.
7.Therapeutic Effect of Guxi Recipe 2 Combined with Joint Loosening Training for Postoperative Ankylosis in Tibial Plateau Fracture Patients
Kangzhen WANG ; Zhongqing WU ; Jianbang TANG ; Jiansong YANG
Journal of Guangzhou University of Traditional Chinese Medicine 2000;0(04):-
Objective To observe the effect of Guxi Recipe 2 combined with joint loosening training for the treatment of postoperative ankylosis in tibial plateau fracture patients.Methods Thirty-two patients with postoperative ankylosis had active exercise combined with small-range continuous passive motion(CPM) 2 weeks after operation,and received steaming and washing with Guxi Recipe 2(mainly composed of Herba Menthae,Radix Saposhnikoviae,fermented soybean,Rhizoma et Radix Notopterygii,Ramulus Cinnamomi,Radix Clematidis,Radix Pterospermi Heterophylli,Radix Angelicae Pubescentis,Olibanum,Cortex Acanthopanacis,and Myrrha) combined with CPM and manipulation for loosening joint 3 weeks after operation.The function of knee joint was assayed with the criteria of knee joint function evaluation issued by the Hospital for Special Surgery(HSS) 6 and 12 months after operation.Results The results of knee joint function scoring showed that the therapeutic effect was excellent in 21 patients,good in 8,average in 3,and the excellent and good rate was 90.6%.Conclusion Guxi Recipe 2 combined with joint loosening training is effective on the recovery of knee joint function of tibial plateau fracture patients with postoperative ankylosis.
8.The experimental study of cell density mediated integrin αγβ6 expression and MMP-9 secretion in colon cancer cells
Guangyun YANG ; Kesen XU ; Zhongqing PAN ; Guiling QI ; Nanhai SHOU ; Jun NIU
Chinese Journal of General Surgery 2008;23(8):614-617
Objective To detect the effect of cell density off both integrin αγβ6 expression and matrix metalloproteinase-9(MMP-9)secretion in colon cancer cells. Methods Flow cytometry was applied to analyze αγβ6 expression in human WiDr colon cancer cell lines and human HaCaT keratinocyte cells, respectively,at high-and low-cell density culture.The MMP-9 aetivity level for various coloIl cancer cell lines, WiDr and SW480 cells at high-and low-cell density culture was analyzed using Biotrak MMP-9 activity assay and Gelatin Zymography assay, respectively. Results High cell density significantly enhances integrin αγβ6 expression for WiDr cells expressing αγβ6 compared with low density,but no increase was observed for human keratinocyte HaCaT cells. Biotrak MMP-9 assay indicated that the amount of MMP-9 secreted per cell for WiDr and SW480 B6 cells at high cell density culture was(3.3±1.2)×10-7ng/cell and(27.2±3.0)× 10-7ng/cell respectively; However,at low cell density it was(1.8±0.7)× 10-7ng/cell and(10.9±2.0)×10-7 ng/cell,respectively. It was 2-3-fold higher for WiDr and SW480 β6 cells at high cell density compared with that at low cell density, but no density-dependent increase observed for SW480 wild cells lack αγβ6 expression(t=0.47,P>0.05),MMP-9 secretion for SW480 wild cells was(3.9±1.7)× 10-7 ng/cell at hish cell density and(3.8 ±0.7)×10-7 ng/cell at low eell density(P>0.05),respectively. Gelatin zymography assay also indicated that the level of MMP-9 in SW480 B6 cells expressing αγβ6 was evidently higher at high density than at low density, however no density-dependent increase observed for SW480 wild cells and HaCaT cells. Conclusions High cell density induces integrin αγβ6 expression and promotes MMP-9 secretion in colon cancer cells, which constitutes the basis for a self-perpetuating system of tumor infiltrating growth in colon cancer progression.
9.Concurrent versus sequential adjuvant radio-chemotherapy after mastectomy for breast cancer: a Meta-analysis
Qing MA ; Yali LIU ; Zhongqing ZHENG ; Yaoyao REN ; Kehu YANG ; Li MA
Chinese Journal of General Practitioners 2010;09(10):723-725
With computer and manual search of literatures on the comparison of concurrent with sequential adjuvant radio-chemotherapy after mastectomy for breast cancer, 4 eligible randomized controlled trials were found; the RevMan 5.0 software was used for Meta-analysis. The results showed that concurrent radio-chemotherapy reduced local recurrence more prominently than sequential radio-chemotherapy in patients with positive axillary lymph nodes( P = 0. 003 ). However, differences in 5-year overall survival,5-year disease-free survival and metastasis-free survival between two groups were not significant (P =0. 670,P =0. 200, P =0. 350).
10.Clinical application of covered endoscophageal stent in treatment of terminal esophageal carcinoma and malignant esophageal fistula in elderly patients
Shu LI ; Bangmao WANG ; Wentian LIU ; Yulong YANG ; Weili FANG ; Zhongqing ZHENG
Chinese Journal of Geriatrics 2011;30(2):138-140
Objective To explore the effect of covered endoesophageal stent in treatment of terminal esophageal carcinoma complicated with malignant esophageal fistula in the elderly. Methods The covered endoesophageal stent was placed at the focus of lesion for each elderly patient in guidance by the iron wire and the stent-transporter under the endoscopy or X-ray. Results All of the stents were successfully implanted in 225 elderly patients without technical failure. The fistula was fully closed in all 19 patients. The symptoms of dysphagia and bucking were relieved obviously in 184cases (81.8%). The 176 cases (78.2%) of patients could have semi-fluid food in first week after stent implant, then have full meal. The inspiration pneumonia caused by fistula was brought under control. Conclusions For elderly patients with esophageal carcinoma, when they lose the operative opportunity or can not tolerate an operation, the treatment with covered endoesophageal stent is effective and safe.