1.Results of monitoring indicators of iodine deficiency disorders in Guangming District of Shenzhen City in 2010-2012
Chao YI ; Zhongping ZHU ; Tieqiang WANG
Chinese Journal of Endemiology 2014;33(1):72-73
Objective To know the current situation of prevention and control of iodine deficiency disorders in Guangming District of Shenzhen through analyzing related monitoring indicators from 2010-2012.Methods According to the National Iodized Salt Monitoring Program,in Guangming District of Shenzhen,2 Street Offices were chosen,then 4 Neighborhood Committees were chosen in each Street Office randomly,15 household salt samples were selected randomly in each Neighborhood Committee; 5 primary schools were chosen in this district,and 20 urine samples were selected from 8-10 years old children in each school in 2011,one source water and one tap water sample were collected of all the water supply companies in this district in 2012.Salt iodine was determined by direct titration method; urinary iodine was determined by As3--Ce4+ catalytic spectrophotometry method; water iodine was determined by sulfate Ce catalytic spectrophotometry of drinking water standard test method.Results Salt iodine were 27.13 and 21.23 mg/kg in 2010 and 2012,respectively.The rates of qualified iodized salt in 2010 and 2012 were 93.33% (112/120) and 90.00% (108/120),respectively.The median concentration of urinary iodine of 8-10 years old children in 2011 was 208.19 μg/L.The median concentration of water iodine in 2012 was 31.60 μg/L.Conclusions The district isn't an iodine excess.The rates of qualified iodized salt in resent years are in line with national standards.There is no iodine deficiency in children and additional supplementation of iodine is not necessary.But relevant monitoring still needs to be improved.
2.Guided bone regeneration with acellular dermal matrix as a barrier for bone defects
Renjie JIA ; Yuqing REN ; Hao XU ; Weiying WANG ; Zhongping YI ; Baodong ZHAO
Chinese Journal of Tissue Engineering Research 2016;20(30):4442-4448
BACKGROUND:Acel ular dermal matrix has good biocompatibility and absorbability and exhibits superiority in the guided bone regeneration. OBJECTIVE:To compare the histological changes and osteogenic effects in bone defects after guided bone regeneration with acel ular dermal matrix and Bio-Gide membrane. METHODS:Mandibular second, third and fourth premolars and the first molars bilateral y were extracted from 12 beagle dogs. Three months later, four three-wal bone defect models in the mandible of each dog were made, and randomized into acel ular dermal matrix plus bone graft group (acel ular dermal matrix group), Bio-Gide plus bone graft group (Bio-Gide group), bone graft group, and blank control group (no treatment). In the former two groups, acel ular dermal matrix and Bio-Gide were used to cover the bone grafts, respectively. RESULTS AND CONCLUSION:After surgery, al the beagle dogs recovered wel . Al the groups except the control group showed dramatical improvement in histological changes and percentage of new bone area, and this improvement was more significant in the Bio-Gide and acel ular dermal matrix groups. Moreover, there was no significant difference between the Bio-Gide and acel ular dermal matrix groups. Therefore, the acel ular dermal matrix can be a candidate for bone repair instead of Bio-Gide membrane in the clinical practice.
3.Expressions of vascular endothelial growth factor and transforming growth factor-beta1 by the intima of balloon-injured rabbit carotid arteries
Yi ZHANG ; Yulian YANG ; Ying GUO ; Baiqin OU ; Zhongping NING ; Yangping LUO ; Bo CUI ; Mingqiang TANG ; Qinhua FU
Journal of Chinese Physician 2001;0(10):-
Objective To establish a rabbit model of restenosis and analyze the expressions of VEGFmRNA and TGF-?_1mRNA during the intimal proliferation.We also explored the relationship between VEGFmRNA,TGF-?_1mRNA and restenosis.Methods 40 healthy male New Zealand white rabbits were evenly divided into three injury groups and one control group.Right carotid arteries were injured with PCI balloon in the injury groups.10 rabbits of each injury group were sacrificed on weeks 1,2 and 4 after the injury.VEGFmRNA and TGF-?_1mRNA were examined by in situ hybridization.All the samples were analyzed using a computerized imaging analysis system.Results In the injury groups,neointimal areas were significantly larger than those in control group(P
4. Physical fitness and its regional distribution of Chinese students aged 13 to 18 in 2014
Bo WEN ; Rongbin XU ; Zhongping YANG ; Yi SONG ; Zhenghe WANG ; Yanhui DONG ; Jun MA
Chinese Journal of Epidemiology 2019;40(6):616-620
Objective:
To evaluate the physical fitness and its regional distribution of students aged 13-18 years in China, using the National Standards for Students’ Physical Fitness (revised in 2014).
Methods:
We recruited 105 834 students aged 13 to 18 years from the Chinese National Survey on Students Constitution and Health project in 2014. Related total scores, rates for qualified and for excellence (the proportions of individuals whose total score greater than or equal to 60.0 or 90.0) of these students were gathered.
5.Association between blood glucose control and mild cognitive impairment in patients with diabetes mellitus and small-artery occlusion
Yunyan HE ; Yi JIN ; Wenjuan ZHAO ; Yan HONG ; Guanen ZHOU ; Yonghong XING ; Zhongping AN
Chinese Journal of Neuromedicine 2018;17(5):491-496
Objective To study the association between blood glucose control and mild cognitive impairment (MCI) in patients with diabetes mellitus and small-artery occlusion (SAO).Methods A screening study of cognitive impairment was conducted in the 676 patients diagnosed with SAO who had been treated at Department of Neurology,Huanhu Hospital from January 2010 through June 2017.They were divided into a normal cognition group (n=629) and an MCI group (n=47) according to the screening results.They were also divided into 4 groups according to their history of diabetes and levels of hemoglobin Alc:normal blood glucose group (n=398),stringent goals group (n=59),general goals group (n=46) and goals-not-met group (n=173).The differences were compared in terms of Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment Scale (MoCA) scores between the normal blood glucose,stringent goals,general goals and goals-not-met groups.We also analyzed the general clinical data and risk factors between the normal cognition and MCI groups.Variables of confounders that were identified as significant were entered into logistic regression.Results There were significant differences in MMSE and MoCA scores between the 4 groups (P<0.05).Between the normal cognition and MCI groups,significant differences were found in proportion of smokers,blood glucose level and severity of stroke (P<0.05).Logistic regression analysis showed that compared with the normal blood glucose group the incidence of MCI was 2.707-fold higher in the stringent goals group (OR=2.707,95% CI:1.035~7.083,P=0.042),2.963-fold higher in the general goals group (OR=2.963,95% CI:1.064~8.277,P=0.038) and 2.604-fold higher in the goals-not-met group (OR=2.604,95% CI:1.269~5.341,P=0.009).Conclusions MCI is more likely to occur in acute phase in patients with diabetes and SAO stroke.The patients can benefit from joint managements of diabetes,stroke and cognitive dysfunction in clinical practice.
6.Analysis on prevalence of physical activity time < 1 hour and related factors in students aged 9-22 years in China, 2014
Zhenghe WANG ; Yanhui DONG ; Yi SONG ; Zhongping YANG ; Jun MA
Chinese Journal of Epidemiology 2017;38(3):341-345
Objective To explore the prevalence of physical activity time <1 hour and related factors in students aged 9-22 years in China.Methods A total of 220 159 students (110 039 boys and 110 120 girls) aged 9-22 years who completed the questionnaire of physical activity and lifestyle behaviors were selected from "2014 National Physical Fitness and Health Surveillance" for the current study.All the participants were divided into 2 groups,i.e.physical activity time < 1 hour and physical activity time ≥ 1 hour according the suggestion of Central Government,stratified by age and gender.x2 tests were used to compare the difference in the prevalence of physical activity time < 1 hour between boys and girls in every age groups.Univariate and multivariate log-binomial regression models were used to explore the factors that influenced the prevalence of physical activity time < 1 hour.Results The boy's prevalence of physical activity time <1 hour was 73.3%,with the lowest (57.0%) in 9-years-old group,and highest (82.5%) in 18 years old group.The girl's prevalence of physical activity time < 1 hour was 79.1%,with the lowest (60.1%) in 9-years-old group,and highest (89.8%) in 21 years old group.Overall,The prevalence of physical activity time < 1 hour was significantly higher in girls than in boys (P<0.001),and the prevalence were significantly higher in girls than in boys in all the age groups (P<0.001),and it was observed that the prevalence of physical activity < 1 hour increased with age in both boys and girls (P<0.001).Multivariate log-binomial regression model found that being girl (PR=1.05,95%CI:1.05-1.06),parents' disliking children to participate physical activity (PR=1.08,95%CI:1.07-1.09),heavy homework (PR=1.13,95%CI:1.12-1.14),long homework time (PR=1.08,95%CI:1.07-1.08),long time spending on electronic screen watching (PR=1.01,95%CI:1.00-1.01) and disliking physical class (PR=1.11,95%CI:1.10-1.12) could be the risk factors for physical activity time < 1 hour,however,living in rural area (PR=0.99,95%CI:0.98-0.99) and no supporting from parents for children to participate physical activity (PR=0.99,95%CI:1.98-1.00) could be the protective factors,but no consistent association with the time of TV watching was observed (P=0.226).Conclusions The prevalence of physical activity time < 1 hour was high in students aged 9-22 years in China.Female,parents;disliking children to participate physical activity,heavy homework,long homework time,long electronic screen watching time and disliking physical class might be the risk factors.