2.The study of intoxication and toxicity of Fructus Xanthii.
Journal of Integrative Medicine 2003;1(1):71-3
Fructus Xanthii is commonly used in rhinology, especially used in treatment of chronic rhinitis and sinusitis. But Fructus Xanthii is toxicant, and it maybe result in poisoning when used excessively, without preparation or in inappropriate preparation. This article reviewed all poisoning cases from 1960 to 2000, its toxicology and methods for detoxification
3.Analysis on results before and after implementing total quality control on blood culture
Zhonghua ZHU ; Maohai ZHANG ; Guihua ZHANG
International Journal of Laboratory Medicine 2016;37(7):933-934,937
Objective To observe the changes of the blood culture results before and after implementing the quality control on blood culture .Methods The blood culture results in 1 year before implementing the quality control and in 1 year after implementing the quality control were performed the contrastive analysis .Results After implementing the quality control on blood culture ,the positive rate of blood culture was elevated by 2 .4% and the pollution rate was decreased by 8 .6% after the quality control .Conclu‐sion Implementing the total quality control on blood culture can improve the positive rate of blood culture and reduces the pollu‐tion rate of blood culture .The determination of contamination bacteria must combine the laboratory detection data with the clinical situation for ensuring to provide accurate and effective antimicrobial agents for clinic .
4.Research on Rescue Device of Forced Landing for Pilots in Air Accidents
Ruodong ZHANG ; Yizhong ZHANG ; Zhonghua ZHENG
Chinese Medical Equipment Journal 2003;0(10):-
Objective To develop rescue device for pilots in air accidents and solve the problem that it's difficult for medical staff to carry out on-board rescue because of the height from the ground to the cockpit edge of the fighter plane. This device with hydraulic system is multi-use: it can be joined to the plane as a ladder and tied in an ambulance as a stretcher. The medical support level of air force dump and station will be improved after using it. Methods 6082 aluminium alloy for aeronautic with advanced and matured technology was utilized to weld the principal part. The fissions can be fitted together and drawn out. The cantilever with hanger was applied. The active and diagonal crutches and the separable composite structure were also used. Results With this device, two staff can board the fighter plane to carry the wounded pilot to the sliding seat which is stably controlled by hydraulic system and then after quick sliding and separating from the device, the seat become a stretcher, and thus it can avoid the second carrying to the pilot. Using this device, the rescue work on-board become faster, more steady and safer. Conclusions This device can provide on-board rescue for pilots of forced landing in air accidents and it can be configured in a new kind of outfield ambulance for both military and civilian purposes. Because of being simple in frame and light in weight, it is easy to take or transport.
5.Methods for Sediment Toxicity Evaluation
Zhonghua ZHAO ; Lu ZHANG ; Xin YU
Journal of Environment and Health 1992;0(05):-
Three widely used methods of sediment toxicity evaluation were introduced in the present paper, including organism toxicity tests, toxicity identification evaluation(TIE) and sediment quality guidelines(SQGs). Compared with the chemical analysis, toxicity tests have an advantage of taking the bioavailability of POPs into account, however, it fails to identify the causative toxicants. TIE, integrating with physicochemical analysis, implicates the specific pollutants in a tiered approach, and by which effective remediation can be designed accordingly. The sediment toxicity can be identified more quickly and appropriately by SQGs than by the former two methods. The differences among the different SQGs constituted by different standards may affect their values for toxicity evaluation. Extensive and reliable SQGs had been acquired to improve their utility. Finally, the combination of chemical analysis, toxicity tests and in situ bioassays will be the trend of sediment toxicity evaluation in the future.
6.The effect of connective tissue growth factor on human renal tubular epithelial cell transdifferentiation.
Chun, ZHANG ; Zhonghua, ZHU ; Anguo, DENG
Journal of Huazhong University of Science and Technology (Medical Sciences) 2004;24(4):350-3
To investigate the role of connective tissue growth factor (CTGF) in transdifferentiation of human renal tubular epithelial cell (HKC), in vitro cultured HKC cells were divided into 3 groups: negtive control, low dose CTGF-treated group (rh CTGF, 2.5 ng/ml) and high dose CTGF-treated (rhCTGF, 5.0 ng/ml). Then the expression of alpha-smooth muscle actin (alpha-SMA) were assessed by indirect immuno-fluorescence, and the percentage of alpha-SMA positive cells were assessed by flow cytometry. RT-PCR were also performed to examine the mRNA level of alpha-SMA. Upon the stimulation of different concentrations of rhCTGF, the expression of alpha-SMA were markedly stronger than that in negative controls. The percentages of alpha-SMA positive cells were significantly higher in the stimulated groups than that of negative controls (38.9%, 65.5% vs 2.4%, P<0.01). alpha-SMA mRNA levels were also up-regulated by the stimulation of rhCTGF (P<0.01). These results suggest that CTGF can promote the transdifferentiation of human renal tubular epithelial cells towards myofibroblast (Myo-F).
Actins/metabolism
;
Cell Differentiation/*drug effects
;
Cells, Cultured
;
Epithelial Cells/*cytology
;
Immediate-Early Proteins/*pharmacology
;
Insulin-Like Growth Factor Binding Proteins/pharmacology
;
Intercellular Signaling Peptides and Proteins/*pharmacology
;
Kidney Tubules/*cytology
7.Fixation features of foveoschisis in pathological myopia
Yunda ZHANG ; Yading JIA ; Zhonghua SHEN
Chinese Journal of Ocular Fundus Diseases 2011;27(3):259-262
Objective To observe the fixation features of foveoschisis in pathological myopia patients.Methods 36 patients(42 eyes)with>-6.00D myopic degree and foveoschisis who diagnosed by optical coherence tomography were included.The patients were divided into foveoschisis with retinal detachment group(11 eyes),foveoschisis with macular hole group(12 eyes)and only foveoschisis group(19 eyes).Micro-perimeter MP-1 was used to identify the fixation location and fixation stability.Results The eccentric fixation were formed above the foyea in the foveoschisis with retinal detachment and foveoschisis with macular hole group,the fixation location was formed on fovea in the only foveoschisis group.The fixation stability of the foveoschisis with retinal detachment,foveoschisis with macular hole and only foveoschisis group were(23±4)0A,(59±6)% ,(91±11)% respectively,the difference was statistically significant(F=243.47,P<0.01).Conclusions The fixation location is formed on foyea in the patients with foveoschisis in pathological myopia.The eccentric fixation is formed above the fovea in the patients who has foveoschisis with retinal detachment and macular hole in pathological myopia.
8.Reaseareh on the effect of the buyang huanwu tang and batroxobin treating sudden deafness
Zhonghua ZHANG ; Xiuping SHI ; Xunhai GUI
Chinese Journal of Primary Medicine and Pharmacy 2008;15(z2):6-7
Objective To determine the effect of the Buyang Huanwu Tang and batroxobin treating sudden deafness.Methods 90 cues(99 ears)with sudden deafness were randomly divided into two groups,the control group were treated with dextran glucose intravenous and lignstrazine,the treat group were treated with the Buyang Huanwu Tang and batroxobin.The periods were 2 weeks.Results The effect in the treat group was more remarkable compared with the control group,there was a significant difference(P<0.05).Conclusion The Buyang Huanwu Tang and batroxobin treeing sudden deafness Can increase curative rete.
9.Effect of esophageal variceal ligation on portal hypertensive gastropathy
Zhonghua SHANG ; Bo ZHANG ; Binglin GUO
Chinese Journal of Minimally Invasive Surgery 2001;0(02):-
Objective To investigate the effect of esophageal variceal ligation (EVL) on portal hypertensive gastropathy (PHG). Methods Gastroscopic examinations were performed both before and after the EVL in 37 cases of PHG. Results The severity of PHG was correlated with the liver functions, and the morbidity of PHG was higher in cases of Child C (100%, 9/9) than in cases of Child A (60%, 12/20) or Child B (80%, 16/20) ( ? 2=18 452,P =0 001). PHG could be exasperated by the application of EVL, but no statistical significance was seen ( ? 2=3 512,P =0 173). On re-examination of gastroscopy 6~12 months later, no relapse or re-bleeding of esophageal varices or gastric mucosa hemorrhage occurred. Conclusions The worse the liver functions, the higher is the incidence of PHG. EVL treatment creates a tendency to aggravating PHG.
10.Use of dexamethasone in combination with azasetron for postoperative nausea and vomiting after laparoscopic cholecystectomy-A randomized controlled trial
Minghui CAO ; Zhonghua CHU ; Lei ZHANG
Chinese Journal of Minimally Invasive Surgery 2005;0(10):-
Objective To observe the effectiveness of dexamethasone combined with azasetron for the prevention of postoperative nausea and vomiting(PONV) in patients after laparoscopic cholecystectomy(LC).Methods A total of 150 ASA(Ⅰ~Ⅱ) patients undergoing an elective LC were randomly divided into three groups with 50 patients in each group: Group D+A was given intravenous dexamethasone 5mg and azasetron 10mg(2ml) at the end of surgery,Group A received intravenous azasetron 10mg(2ml) at the end of surgery,and Group C received normal saline(NS) 2 ml as the control.Episodes of nausea and vomiting were recorded for 24 h following the surgery.Results The incidence of nausea was 4% in the Group D+A(2/50),which was significantly lower than in the Group A(16%,8/50) and the Group C(34%,17/50)(?~2=4.00 and 14.62;P=0.046 and 0.000).The incidence of vomiting was 2% in the Group D+A(1/50),which was significantly lower than in the Group A (14%,(7/50)) and the Group C(32%,16/50)(?~2=4.89 and 15.95;P=0.027 and 0.000).The incidences of nausea and vomiting were significantly lower in the Group A than in the Group C(?~2=4.32 and 4.57;P=0.038 and 0.033).Conclusions Use of a low dose of dexamethasone in combination with azasetron is more effective than azasetron prophylaxis alone for a successful control of PONV after LC.