1.Effect of early fluid resuscitation on the prognosis of severe acute pancreatitis
Chinese Journal of Pancreatology 2011;11(6):386-389
ObjectiveTo investigate the effect of early fluid resuscitation on the prognosis of SAP patients.MethodsPatients who were admitted to our hospital within 72 h after the onset of the SAP were enrolled.The parameters for the fluid resuscitation were as follow: heart rate <120 beat/h,urine output ≥ 1 ml ·h-1 · kg-1,hematocrit ≤35% and mean arterial pressure 65 ~ 85 mmHg ( 1 mmHg =0.133 kPa).The effects of different time of reaching fluid resuscitation ( <48 h,48 -72 h,>72 h) and parameters achieved (0 ~ 1parameter,2 parameters,3 parameters,4 parameters) on the prognosis were analyzed.ResultsThere were 70 patient enrolled in this study and 41 ( 58.6% ) developed complications,20 ( 28.6% ) were referred to surgical operation and 10( 14.3% ) died.The median hospital stay was 23.5 d,and the median medical cost was 71.9(5.7~567.4 thousands RMB).The rates of surgical intervention in <48 h,48 ~72 h,>72 h groups were 20.0%,33.3%,75.0%,and the rates of acute kidney injury were 20.0%,25.0%,75.0%,while the rates of complications were 50.0%,83.3%,100%,and the difference among the 3 groups was statistically significant (P < 0.05 ).The rates of surgical intervention in patients achieving 0 ~ 1,2,3,4parameters within 48h of SAP onset were 50.0%,26.3%,13.0%,25.0%,and the rates of acute kidney injury were 45.0%,31.6%,17.4%,0,while the rates of ARDS were 35.0%,31.6%,13.0%,0,which showing a significant decreasing trend.ConclusionsAn appropriate fluid resuscitation in the first 48 h after the onset of SAP was benefit for improving the treatment effects and patients' outcome.
2.Application of Server Virtualization in Medical Data Center
Journal of Medical Informatics 2017;38(5):29-33
The paper introduces the current status and the problems of servers in the data center of Institute of Medical Information,Chinese Academy of Medical Sciences,points out the necessity of virtualization in data center,expounds the concept of virtualization and server virtualization technology,then describes the implementation scheme of constructing the server virtualization platform based on VMware vSphere 5.5 products in detail.Finally,the application effect of server virtualization is summarized and the future work is prospected.
3.A case of rhabdomyolysis with compartment syndrome in the right upper extremity
World Journal of Emergency Medicine 2020;11(3):185-187
Acute compartment syndrome refers to a series of
symptoms of muscles and nerves in the compartment
of the fascia due to acute ischaemia and hypoxia. It is
more common in the volar and calf of the forearm.[1]
Due to long-term ischaemia of muscles and nerves in
the fascia, muscle necrosis and neurological dysfunction
can occur, causing serious irreversible damage to
the limbs. However, rhabdomyolysis is one of the
major complications in the absence of fractures or
other trauma. Rhabdomyolysis syndrome refers to the
destruction and disintegration of striated muscle caused
by various causes, by which intracellular components
such as creatine kinase and myoglobin enter the blood
circulation, causing systemic disorders in the body and
even acute renal failure and other clinical syndromes.[2]
This case introduces rhabdomyolysis induced by skeletal
muscle ischaemia and hypoxia caused by upper limb
compression after drinking, accompanied by upper limb
compartment syndrome.
4.Renal cell carcinoma in young patients:clinicopathoiogic characteristics
Ming YUAN ; Han-Zhong LI ; Ming XIA ;
Chinese Journal of Urology 2000;0(12):-
Objective To study the clinical features,pathological characteristics and prognosis of renal cell carcinoma(RCC)in young adults,and to improve the recognition of RCC in young population. Methods The data of 35 young patients with RCC under the age of 35 years from August 1983 to June 2005 were analyzed retrospectively.There were 22 males and 13 females with a mean age of 31 years(age range, 19-35 years).The clinical presentations were as follows:painless hematuria in 12 cases(34%),low back pain in 12(34%),abdominal mass in 2(6%),fever in 3 and Stauffer syndrome in 1.The tumor size was 1.2-13.8 cm in diameter(mean,6.0cm).AJCC staging showed stage I tumor in 8 cases,stageⅡin 4, stageⅢin 18 and stageⅣin 5.Of the 35 cases,28 underwent radical nephrectomy(including simultaneous extraction of the vena cava emboli in 3 cases and extraction with pulmonary lobectomy in 1);5 cases under- went partial nephrectomy;and 2 cases lost the chance of operation(1 of them had biopsy).Results The operations were successful.The postoperative pathologic diagnoses consisted of clear cell carcinoma in 23 ca- ses,mixed cell carcinoma in 5,papillary cell carcinoma in 2,and chromophobe cell carcinoma in 2,low-dif- ferentiated and undifferentiated cell carcinoma each in 1.Of them,26 cases were followed for 12-148 months(mean,56 months).Postoperative 3-and 5-year survival rates were 65% and 50%,respectively. Conclnsions In young population,RCC is difficult to diagnose because of occult symptoms at early stage and lack of tumor specificity,which leads to relatively late clinical staging at diagnosis.RCC is characterized by higher malignancy,easy invasion to surrounding tissues and metastasis,and thus poor prognosis.
5.Effects of bovine plasma fibronectin on the proliferation and differentiation of rat osteoblasts in vitro
Xue MING ; Zhang YING ; Zhong MING
Journal of Practical Stomatology 2000;0(06):-
Objective: To investigate the effects of bovine plasma fibronectin on the proliferation and differentiation of rat osteoblasts. Methods:Rat osteoblasts were cultured and identified. AlamarBlue were used to determine the effect of various concentration of bovine plasma fibronectin on the proliferation of the osteoblasts. ELISA method was used to determine the alkaline phosphatase activity of the cells. Results: Fibronectin stimulated the proliferation of rat osteoblasts at 40 ?g/ml (P
6. Analysis on clinical therapeutic efficacy of 49 cases with hilar cholangiocarcinoma
Tumor 2007;27(9):744-746
Objective: To investigate the related factors for the therapeutic efficacy of hilar cholangiocarcinoma. Methods: A retrospective clinical analysis was performed on the clinical data from 49 patients with hilar cholangiocarcinoma. Results: The mean survival time was 19.5 months, 8.79 months, and 5.44 months for the total 49 patients who received radical resection, palliative resection, and drainage operation, respectively. The mean survival time was 23.5 months, 9.37 months, and 2.90 months for patients at AJCC TNM stage I and II, III, and IV (IVa and IVb), respectively. The mean survival time was 3.62 months for patients with a total bilirubin level more than 300 μmol/L or 14. 74 months for those patients with a total bilirubin level less than 300 μmol/L. The mean survival time was 5.68 months, 11.59 months, and 22.17 months for patients whose total serum bilirubin level was more than 40 μmol/L, between 20 to 40 μmol/L, and less than 20 μmol/L one week after operation, respectively. Conclusion: TNM stage and curative resection degree are the main related factors influencing the therapeutic efficacy of hilar cholangiocarcinoina. The decreased degree in the serum level of total bilirubin before and after surgery has the potential to be used as a marker to predict the long-term therapeutic efficacy of hilar cholangiocarcinoma.
8.Ability of independent creative learning of students majoring in preventative medicine should be promoted rather than be taught
Baoqing MO ; Caiyun ZHONG ; Ming ZHOU
Chinese Journal of Medical Education Research 2012;11(7):682-685
Preventive medicine is a highly practical vocation; the students majoring in this major should be trained with abilities of active learning and flexible applying.Nowadays,the main teaching methods in many colleges and universities were assigning homework,communicating on the internet and posing questions in the class,which were only taught by the teacher.The promotion model may promote the knowledge application for the students,with the heuristic teaching in the class based on the virtual or scenic status,practice in scientific research,social service and experiments in the real sites.Through promotion model,students can combine the theoretical knowledge with the reality,learn creatively and apply the knowledge flexibly.
9.The application of the endovascular distal parent artery occlusion in vertebral artery dissecting aneurysms involving the posterior inferior cerebellar artery
Kuang ZHENG ; Ming ZHONG ; Xianxi TAN
Chinese Journal of Postgraduates of Medicine 2012;(35):1-4
Objective To investigate the application of endovascular distal parent artery occlusion in vertebral artery dissecting aneurysms involving the posterior inferior cerebellar artery.Methods The clinical and follow-up data of 5 patients with vertebral artery dissecting aneurysms involving the posterior inferior cerebellar artery who received the endovascular distal parent artery occlusion were retrospectively analyzed.Results Complete occlusion of dissected arterial and aneurysm segments was achieved in 4 patients.After followed up 6-12 months,angiography showed no recurrence or neurological deficit.Continued filling of the dissected aneurysm was observed in 1 patient's follow-up angiography,but without rehaemorrhagia or neurological deficit.Conclusions The endovascular distal parent artery occlusion is a safe and efficient choice for treating vertebral artery dissecting aneurysms involving the posterior inferior cerebellar artery,which keeps the posterior inferior cerebellar artery flowing unobstructed while clipping the dissecting aneurysm.
10.Practice and thoughts on the social responsibility of private hospitals
Liyan LI ; Ming ZHONG ; Qiong DAI
Chinese Journal of Hospital Administration 2011;27(3):223-225
The paper introduced the organization culture building of a private hospital, in creating the Aikang hospital as your home culture and Aikang values for building a harmonious workplace for the hospital. The management system reform features the separation between regulations and management,building of the supporting system and operating system, for better quality of care with advanced management practice. The social rewards feature great efforts in supporting the disadvantageous population, and undertaking public health service and charity activities. These care and love to the community help the hospital to fulfill its social responsibilities.