4.EFFECT OF GRAPE PROCYANIDIN ON PLASMA GMP140 AND TXB_2 IN RATS FED WITH HIGH FAT DIET
Acta Nutrimenta Sinica 2004;0(05):-
Objective:To study the effect of grape procyanidin (GPC) on the levels of plasma?-granule membrance protein 140 (GMP140) and thromboxane B2 (TXB2 ) in rats. Method:Wistar rats fed by high fat diet (HFD) were given GPC i.g. at different doses for 6 w, and the levels of plasma GMP140 and TXB2 were examined by radioimmunoassay (RIA). Result:Plasma GMP140 and TXB2 levels of high dose GPC were respectively 7.89?1.02ng/ml, 131.71?42.13 pg/ml, significantly lower than those of HFD group. Conclusion:GPC could inhibit the increase of plasma GMP140 and TXB2 induced by high fat diet in rats.
5.Clinical Observation on Chinese Herbal Medicine Combining with the Therapeutic Instrument of Amblyopia for Amblyopia
Journal of Guangzhou University of Traditional Chinese Medicine 2000;0(04):-
【Objective】To investigate the therapeutic effect of Chinese herbal medicine combining with the therapeutic instrument of amblyopia for the treatment of amblyopia.【Methods】One hundred amblyopia patients were divided into group A(94 eyes in 50 cases) and group B(95 eyes in 50 cases) by the method of simple randomization.Patients in group B wore appropriate glasses,and covered the eye with a better sight when the sight difference over 2 lines or covered the eyes alternatively when the sight difference below 2 lines.Meanwhile,patients in group B were treated by the curative instrument of amblyopia(micro-lightbrush).Patients in group A were treated with herbal medicine with the actions of strengthening spleen and tonifying kidney,tonifying essence and nourishing blood(Radix Codonopsis,Rhizoma Dioscoreae,Fructus Lycii,Fructus Mori,Semen Cuscutae,Semen Cassiae,Rhizoma Polygonati,Radix Rehmanniae Preparata,Radix Paeoniae Alba,pericarpium Citri Reticulatae,Radix Puerariae) additonally.Fifteen days constituted one treatment course and an interval of 5 days was between two courses.The two groups were treated for one successive year.After treatment,the total therapeutic effect,effect in different age groups and effect in patients with different degrees of amblyopia were compared between the two groups.【Results】In group A,69(73.4%) eyes were cured,21(22.3%) effective and 4(4.3%) ineffective,and 58(61.1%),25(26.3%) and 12(12.6%)in group B,respectively.The total therapeutic effect in group A was superior to that in group B(P0.05),but the effect was superior to that on patients aged 9 years and older in the two groups(P0.05).However,for the patients with severe amblyopia,the effect was better in group A than that in group B(P
8.The damages of adrenal gland in rabbits with neisseria memingococcal septic shock
Kaihe DU ; Guoqing YIN ; Be ZHONG
Chinese Journal of Pathophysiology 1989;0(06):-
AIM: To investigate the damages of adrenal gland in rabbits infected with neisseria meningococci(MC).METHODS: 18 rabbits were injected with MC (1?10 11 organism/kg, iv, model group, n=10 ) or normal saline (control group, n=8 ).TNF-? was detected in baseline (before challenged), 60 min and 120 min after injection. 120 min after injection, TNF-? immunochemical localization of adrenal gland was detected with ABC methods by electron microscopy. RESULTS: In model group, TNF-? positive cells were located in medulla and TNF-? released into simus of medulla. The medulla damages were appeared but gland cells of cortex was normal. No damages were showed in control group. TNF-? value of plasm was elevated at 60 min and 120 min after injection compared with control group. CONCLUSION: TNF-? was released into medulla and resulted in medulla damages after MC challenging. Adrenal cortex didnt damaged in early phase of MC septic shock. [