Objective: To explore the relationship between serum levels of carbohydrate antigen 125 (CA125) and hemodynamic changes in patients with chronic heart failure (CHF).
Methods: A total of 110 CHF patients with clear diagnosis, admitted in our hospital from 2013-01 to 2014-06 were studied. According to NYHA classiifcation, the CHF patients were divided into 3 groups: NYHA I-II group,n=40, NYHA III group,n=38 and NYHA IV group,n=32. There was a Control group including 40 subjects from healthy physical examination. The levels of CA125, B-type natriuretic peptide (BNP), left ventricular ejection fraction (LVEF) were recorded at admission, discharge and 3 months follow-up period; the relationship between CA125, BNP and LEVF were studied in CHF patients.
Results:①In CHF patients, the levels of CA125 and BNP increased with NYHA classification by NYHA I-II group > NYHA III > group > NYHA IV group accordingly,P<0.05; while LVEF decreased with the elevated NYHA classiifcation, allP<0.05.②Correlation study indicated that CA125 positively related to BNP (r=0.64,P<0.001), LAD (r=0.28,P<0.01), LVEDD (r=0.35,P<0.001), and negatively related to LEVF (r=-0.63,P<0.001).③After treatment, the serum levels of CA125 in NYHA III group and NYHA IV group were obviously decreased,P<0.05.④There were 27 patients died at in-hospital and follow-up period, their levels of CA125 were (110.3 ± 40.2) before treatment and (67.1 ± 20.2) after treatment; for 83 survivors, their levels of CA125 were (66.7 ± 30.6) before treatment and (50.3 ± 24.5) after treatment, allP<0.05.
Conclusion: Serum level of CA125 is positively related to the severity of CHF, it might be used as a serum predictor for prognosis in CHF patients.

Objective:To establish a method for the determination of rutin in Anoectochili roxburghii. Methods:The detection was carried out by HPLC. A Lanbo-Kromasil C18 column(250 mm × 4. 6 mm,5 μm) was used with methanol-0. 2% phosphoric acid solu-tion (40∶60) as the mobile phase;the detection wavelength was 257nm, the flow rate was 1. 0 ml·min-1 and the column temperature was 30℃. Results:Rutin showed a good linear relationship within the range of 0. 021-0. 433 μg(r=0. 999 6). The average recovery was 96. 65%(RSD=1. 67%, n=9). Conclusion:The method is simple, rapid, specific and reproducible.

Contemporary social developments and changes have greatly influenced university students’thought and psychology,for the universities of ideological and political education not only brings the opportunity,but also brings the challenges.The universities of ideological and political education work to strengthen mental health education,in practice,can improve the universities of ideological and political education work more targeted and effective.

The eosinophilic otitis media(EOM) is an intractable disease characterized by the presence of a highly viscous yellow effusion with extensive accumulation of eosinophils in the middle ear; granulation tissue can been discovered in the middle ear cavity; most of patients have association with bronchial asthma; resist to conventional treatment for otitis media; EOM patients show gradual deterioration of hearing and sometimes become deaf suddenly; effective treatment involves use of topical and oral steroids. This article summarizes the progress of the EOM's diagnosis and treatment.
Asthma ; complications ; Ear, Middle ; physiopathology ; Eosinophilia ; pathology ; Eosinophils ; Hearing Loss ; complications ; Humans ; Otitis Media ; pathology

Objective: To investigate the undertected situation in gonococci culture of male urethral secretions. Methods: The 362 cases of male ureethral secreations were simultaneously detected with fluorescence quantitative PCR, germiculture and direct smear method. The results in three detections were statistically analyzed. Results: The fluorescence quantitative PCR positive rate was 29.56%, near to direct smear method (26.52%)（x2=0.83，P>0.05）; the germiculture positive rate(4.42%) was significantly lower than the positive rates of fluorescence quantitative PCR(x2=81.10,P<0.01) and direct smear method(x2=67.60,P<0.01). Conclusion The simple gonococci culture has high missed detection rate(>80%) in detecting male cases. Ensuring the quality of samples before analysis and detecting with two methods or above are the effective measures to improve the gonococci detection rate.

OBJECTIVE： To analysis the adverse reactions of angiotension converting enzyme inhibitor（ ACEI） ， so as to deepen the understanding to the ARDs and improve the therapeutic effect of ACEI METHODS： The therapeutic effects and ARDs of ACEI were retrospectively reviewed and the incidence of ARDs induced by ACEI and the relationship between different ACEIs and their ARDs were analyzed RESULTS： （ 1） The incidence of ARDs of ACEI was 12％  Stimulating cough， parageusia， gastrointestinal tract discomfort， skin rash， itch of skin， hypotension， headache， dizziness， proteinuria and angioedema were the common symptoms （ 2） Of five kinds of ACEIs， captopril induced the highest incidence of ARDs and stimulating cough， parageusia， gastrointestinal tract discomfort， skin rash and itch of skin were the most common manifestations CONCLUSION： Stimulating cough， parageusia， gastrointestinal tract discomfort and skin rash are the most common symptoms of ARDs， and the symptoms will disappear when drug administration is discontinued

Shan Qi soy has busting bags, bacteria sum overproof, continue acidification and other problems occasionally during the storage. It's probably caused by the Lactobacillus continue growth in the soy. We tried expounding the relationship between growth and producing acid when Lactobacillus growing in the thin fermented material.

OBJECTIVE:To explore the effects of Xinnaoxin pills on CAT score,cardiopulmonary function and hemorheology of patients with pulmonary heart disease complicating with coronary heart disease. METHODS:In retrospective study,80 cases of pulmonary heart disease complicating with coronary heart disease were randomly divided into control group and observation group with 40 cases in each group. Control group was given routine treatment as relieving asthma,eliminating phlegm and oxygen inhala-tion,anti-infective treatment,correcting acid-base balance,cardiotonic and diuretic treatment. Observation group was additionally given Xinnaoxin pills 1.0 g/time,bid after meal,on the basis of control group. CAT score,cardiopulmonary function and hemorhe-ology index were compared between 2 groups before and after treatment as well as ischemic ECG improvement effect and the occur-rence of ADR after treatment. RESULTS:After treatment,hematocrit hematocrit had changed slightly among hemorheology index-es,and CAT score,other hemorheology indexes and cardiopulmonary function indexes were improved significantly;the improve-ment of observation group was better than that of control group,with statistical significance(P<0.05). Total effective rate of isch-emic ECG was 90.0% in control group and 92.5% in observation group,there was no statistical significance(P>0.05). There was no statistical significance in the incidence of ADR between 2 groups (P>0.05). CONCLUSIONS:Xinnaoxin pills can effectively improve CAT score and cardiopulmonary function of patients with pulmonary heart disease complicating with coronary heart dis-ease. It also can improve hemorheology and shows good clinical efficacy,but great importance should be attached to the safety of drug use in the clinic.

Objective:To evaluate the technique of reduction and rigid internal fixation of sagittal maxillary fracture. Methods:15 cases of sagittal maxillary fracture were reviewed. Occlusal guide plates were prepared preoperatively by model surgery analysis in 10 cases; Le Fort ? osteotomy and down-fracture were done in 8 cases; Pterygomaxillary junctions were also separated in the other cases. Internal fixation was applied along the anterior maxillary surface by using microplates in all 15 cases. Results:Anatomically reduction was achieved in all cases; Occlusion of 14 cases was corrected except one case of fracture re-displaced. Conclusion:Orthognathic technique is effective treatment of sagittal maxillary fracture; One microplate applied along anterior maxillary surface may be not enough to ensure the fixation of sagittal maxillary fracture.

Objective: To investigate the principle of diagnosis and treatment of orbital fracture. Methods:114 cases of orbital fractures were reviewed. The incidence of major clinical feature was estimated and the surgical procedures were analyzed. Results:Incidence rate of restricted ocular motility, diplopia and enophthalmos were 63.2%, 62.3% and 59.6% respectively; The incidence of optic nerve injury, lacrimal injury and rupture of the globe was 15.8%,15.8% and 12.3% respectively. 95.6% of the cases were undergone orbital wall reconstruction (artificial bone graft) and 72.8% were received fracture reduction and internal fixation. Conclusion:Restricted ocular motility, diplopia and enophthalmos are major symptoms of orbital fracture and optic nerve injury, lacrimal injury and rupture of the globe are important complications of orbital fracture; Orbital reconstruction is the most popular surgical procedure for orbital fracture and bone reduction and internal fixation is also need for impure orbital fracture.