1.Bacillus anthracis Infection and Bioterrorism
Journal of Environment and Health 1992;0(05):-
The bioterrorism-related anthrax, the general situation of anthrax prevalence in China and the latest advances in laboratory diagnosis of Bacillus anthracis were reviewed. The control and prevention measures on anthrax were also introduced and the measures responding to the possible bioterrorism-attack were proposed in this paper.
2.The significance of HPV-DNA testing in diagnosis of cervical displasia
China Oncology 2001;0(03):-
0.05).Conclusions:The incidence of CIN and especially high-grade CIN are higher in patients with positive high risk types of HPV-DNA than negative. HPV-DNA testing has significance in the diagnosis of cervical displasia;HPVDNA testing combined with pap smear and colposcopy can increase the diagnosis of cervical diaplasia.
3.Effectiveness evaluation for military equipment
Zhiyi ZHANG ; Jianxia ZHANG ; Jianzhong SUN
Chinese Medical Equipment Journal 1993;0(05):-
This paper introduces the effectiveness's concept and classification of military equipment. The generation, development and content of effectiveness study are also presented. The typic methods of evaluating equipment's effectiveness are emphasized. The characteristics of effectiveness evaluations for several kinds of equipments are analyzed based on examples.
4.Revelation to Educational Work from Psychological Basic Theory
Haihong ZHANG ; Zhiyi ZHANG ; Hui WANG
Chinese Journal of Medical Education Research 2003;0(03):-
The article,taking into account basic content of hierarchical theory of needs,human structure theory and mark theory,analyzed the idea and method of procedural education,environmental education and self-governed education for college students.
5.Reforming Communicative Methods and Improving Communication Between Teachers and Students
Haihong ZHANG ; Zhiyi ZHANG ; Yanping ZHAO
Chinese Journal of Medical Education Research 2006;0(09):-
Communication is very important in education.This paper combine common factors in effected educative communication with common problems in communication between teachers and students.From systemic and analyzing point of view,discuss promotion of communicative quality that contains surroundings and methods and so on.
6.A study on microvessel density, VEGF and bFGF in oromaxillofacial sarcoma
Yanmin WANG ; Jieying ZHANG ; Fusheng DONG ; Zhiyi AN
Journal of Practical Stomatology 2010;26(2):217-219
Objective:To explore the role of MVD, bFGF and VEGF in OMFS and the relationship between them. Methods: Immunochemistry streptavidin peroxidase method was used to detect the MVD and the bFGF, VEGF expressions in 57 cases of OMFS samples. Results: MVD, bFGF and VEGF expressions were different between OMFS and benign. The close correlations were found among the expressions of VEGF, bFGF and MVD. Conclusion: The expressions of VEGF and bFGF are associated with MVD which indicated that VEGF and bFGF may play important roles in angiogenesis.
7.Ovarian carcinoma presents as distant metastases without detectable tumors of the origin disease at the first presentation
Rongyu ZANG ; Zhiyi ZHANG ; Shumo CAI
Chinese Journal of Obstetrics and Gynecology 2001;0(07):-
Objective To study the characteristics, therapies and prognosis of the patients with epithelial ovarian cancer (EOC) that are initially categorized as extra abdominal adenocarcinoma of unknown primary Methods Twenty five patients with EOC, who were treated in the Cancer Hospital of Fudan University from Jan 1986 to Dec 1997, and manifesting as extra peritoneal or liver parenchyma metastases at the time of presentation, without detectable ovarian tumors, were retrospectively studied Results Supraclavicular and inguinal lymph node metastases were common in this group of patients, with 6 and 5 cases respectively, and 6 patients with more than two sites metastases simultaneously 16 patients (64%) were optimally surgical debulked 20 patients with stage Ⅳ EOC initially presenting as extra abdominal metastases experienced a better prognosis, with an estimated median survival of 24 months. Of whom the median survival was 30 months in patients presenting with pleural effusion or supraclavicular lymph node metastases Vs 19 months in those with other sites spread ( P =0 026 4) Conclusions The prognosis of such cases, particularly for those with supraclavicular lymphadenopathy or malignant pleural effusion, is a lot better than other stage Ⅳ EOC patients, probably because of most of the patients initially presenting with distant metastases being generally in a good condition competent for aggressive surgery or multi cycle chemotherapy
8.Impacts of chemotherapy on long-term survival of patients with advanced epithelial ovarian cancer
Rongyu ZANG ; Shumo CAI ; Zhiyi ZHANG
Chinese Journal of Obstetrics and Gynecology 2000;0(12):-
6) of platinum based intravenous chemotherapy prolonged the survival of patients with suboptimal cytoreduction Intraperitoneal chemotherapy was one of the dominant long term survival determinants, and mainly on those with size of residual disease less than 1 cm
9.Relationship between endogenous nitric oxide and pulmonary edema caused by overinfusion of colloid
Zhidong XUE ; Jingfan ZHANG ; Zhiyi FAN
Chinese Journal of Anesthesiology 1997;0(11):-
Objective: To investigate the role of endogenous nitric oxide (NO) in the pulmonary edema caused by overinfusion of colloid. Method: Forty healthy rabbits were randomly allocated into (Ⅰ) control group, (Ⅱ) infusion control group: one fold total blood volume of Gelofusine was infused at 2ml?kg~(-1)?min~(-1)(Ⅲ)L-NNA group:LNNA 20 mg/kg was intravenously injected before infusion, (Ⅳ)L-Arg+L-NNA group:L-arginine 300mg/kg and LNNA 20 mg/kg was intravenously injected before infusion. MAP,HR and CVP were recorded during the experiment, arterial blood gas analysis was examined before and after infusion,serumal NO value and lung water content were measured at the end of the experiment. Result: Overinfusion of colloid,L-NNA,an inhibitor of NO synthesis increased the extravascular lung water (EVLW) content and decreased NO value,meanwhile CVP increased,HR,PaO_2 and SaO_2 decreased,excess dose of L-arginine completely reversed the effect of L-NNA. Serumal NO value was negatively correlated with EVLW content (r=-0.94). EVLW content was significantly correlated with total lung water (r=0.41). Conclusion:Endogenous NO can reduce the pulmonary edema caused by overinfusion of colloid.
10.The distribution and it's clinical significance of hepatitis B core antigen in hepatocytes of chronic hepatitis B virus infected patients
Lijuan ZHANG ; Guomin CHEN ; Zhiyi WANG
Chinese Journal of Infectious Diseases 2011;29(6):348-351
Objective To explore the distribution and clinical significance of hepatitis B core antigen( HBcAg) in the hepatocytes of chronic hepatitis B virus infected patients. Methods Paraffin sections were made from 41 liver biopsy samples obtained from chronic hepatitis B virus infected patients. The immuno-fluorescence confocal technique was utilized to analyze the expression level and localization of HBcAg in hepatocytes. The data were analyzed by using Kruskal Wallis test and chisquare test. Results HBcAg expression were detected in 36 (87. 8%) patients, among whom 23 cases had moderate abnormal liver function, 10 with mild abnormal liver function and 3 with normal liver function. Among the cases with moderate abnormal liver function, 6 cases showed the simple membrane-type HBcAg expression, 17 cases showed mixed cytosolic-type and membrane-type HBcAg expression without the nuclear-type expression. Twelve cases with mild abnormal liver function only showed simple cytosolic-type HBcAg expression without membrane-type or nuclear-type expression. In the three patients with normal liver function, HBcAg was expressed in cytoplasm and nuclear but not on membrane. The correlation between HBcAg expression pattern and liver function was statistically significant (χ2 =10. 60, P<0.01). Conclusion HBcAg expression is directly correlated with liver injury in chronic hepatitis B virus infected patients, which indicates that membrane expressed HBcAg is the target antigen during the immuno-attack of liver.