1.The teaching process of surgical nutrition therapy
Bei ZHOU ; Jinfeng ZHENG ; Zhixiu SONG ; Jianhui XUE ; Hongfei SHI
Parenteral & Enteral Nutrition 2017;24(1):52-54
Surgical nutrition therapy is a novel course for undergraduates who are major in food hygiene and nutrition.In this study,the purpose,content,model and specific teaching approaches of the course were discussed,and the essentials of clinical practice for surgical nutrition therapy were pointed out.We hope that our experience would be helpful for the development of the course.
2.Screening and characterization of gastric carcinoma subcell line with higher invasive potential
Zhijiao ZHOU ; Jiansi ZHU ; Xiang OU ; Jianguo ZHOU ; Chengkun WANG ; Fang PENG ; Xiyun QUAN ; Zhixiu ZHOU
Cancer Research and Clinic 2009;21(1):7-10,13
Objective To study a gastric carcinoma subcell line with higher invasive potential and its biologic characteristics screened by a transwell chamber. Methods Transwell chamber was used for the selection of tumor subline. The biological characteristics of the cell lines were studied with optics microscope, Westem blotting, Transwell, immunohistochemical staining and growth curve. Results A gastric carcinoma cell subcell line (named MKN-28S10) was established from its parent cell line MKN-28 with higher invasive potential. MKN-28S10 showed essentially the same morphous as MKN-28. The expression of E-cadherin and TIMP-1 decreased significantly in the screened subcell line(P<0.05). The expression of NM23-H1 in MKN-28S10 was significantly lower than that in MKN-28 (P<0.05). Compared with MKN-28 (61.75±2.06 per vision), the migrative ability of passing through the membrane Millipore(100.25±0.50 per vision) was obviously increased in MKN-28S10(P<0.05). Compared with MKN-28, the growth rate of MKN-28S10 was increased obviously. Conclusion MKN-28S10 cell has stronger invasive ability and more powerful proliferation than that of its mother line MKN-28.
3.The research advances of biomechanics of human knee joint ligaments.
Jibin ZHOU ; Zhixiu HAO ; Yiyong YANG ; Rencheng WANG ; Dewen JIN
Journal of Biomedical Engineering 2006;23(4):903-906
Ligaments are the main parts which stabilize the knee joint. How to analog the ligaments in biomechanical model will affect the characteristics of the human knee dynamics and in the computation of the stress in ligaments between two bones. This symposium is aimed at the survey of the simplified method of the ligaments via mechanical parameters, and providing an exact method of constructing model.
Biomechanical Phenomena
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Humans
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Knee Joint
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anatomy & histology
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physiology
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Ligaments, Articular
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anatomy & histology
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physiology
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Models, Anatomic
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Models, Biological
4.Extending the CONSORT Statement to moxibustion.
Chungwah CHENG ; Shufei FU ; Qinghui ZHOU ; Taixiang WU ; Hongcai SHANG ; Xudong TANG ; Zhishun LIU ; Jia LIU ; Zhixiu LIN ; Lixing LAO ; Aiping Lü ; Boli ZHANG ; Baoyan LIU ; Zhaoxiang BIAN
Journal of Integrative Medicine 2013;11(1):54-63
The STandards for Reporting Interventions in Clinical Trials Of Moxibustion (STRICTOM), in the form of a checklist and descriptions of checklist items, were designed to improve reporting of moxibustion trials, and thereby facilitating their interpretation and replication. The STRICTOM checklist included 7 items and 16 sub-items. These set out reporting guidelines for the moxibustion rationale, details of moxibustion, treatment regimen, other components of treatment, treatment provider background, control and comparator interventions, and precaution measures. In addition, there were descriptions of each item and examples of good reporting. It is intended that the STRICTOM can be used in conjunction with the main CONSORT Statement, extensions for nonpharmacologic treatment and pragmatic trials, and thereby raise the quality of reporting of clinical trials of moxibustion. Further comments will be solicited from the experts of the CONSORT Group, the STRICTA Group, acupuncture and moxibustion societies, and clinical trial authors for optimizing the STRICTOM.
5.Bioactive natural compounds against human coronaviruses: a review and perspective.
Yanfang XIAN ; Juan ZHANG ; Zhaoxiang BIAN ; Hua ZHOU ; Zhenbiao ZHANG ; Zhixiu LIN ; Hongxi XU
Acta Pharmaceutica Sinica B 2020;10(7):1163-1174
Coronaviruses (CoVs), a family of enveloped positive-sense RNA viruses, are characterized by club-like spikes that project from their surface, unusually large RNA genome, and unique replication capability. CoVs are known to cause various potentially lethal human respiratory infectious diseases, such as severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS), and the very recent coronavirus disease 2019 (COVID-19) outbreak. Unfortunately, neither drug nor vaccine has yet been approved to date to prevent and treat these diseases caused by CoVs. Therefore, effective prevention and treatment medications against human coronavirus are in urgent need. In the past decades, many natural compounds have been reported to possess multiple biological activities, including antiviral properties. In this article, we provided a comprehensive review on the natural compounds that interfere with the life cycles of SARS and MERS, and discussed their potential use for the treatment of COVID-19.