1.The effectiveness of the implementations and recommendations for community health services in Beijing
Hongyan ZHAO ; Zhiwei ZHAN ; Zijun ZHOU
Chinese Journal of Hospital Administration 2011;27(10):750-754
It's a new financial management system that our country implemented the management of separating the income and expenditure in the community health services.Beijing is one of the former pilot cities which carried on the management of separating the income and expenditure.To know the effectiveness of the implementations and its influence to the health services,this article analyses the status of community health services,the financial investment and the performance results in Beijing.Considering the above,this paper also provides policy recommendations on the development of health services in Beijing to improve the new urban medical service system which based on the community health services.
2.Endoscopic ultrasonography in gastric cancer: from diagnosis to therapy
Chunyu HUANG ; Wei WANG ; Zhiwei ZHOU
Journal of International Oncology 2011;38(7):540-542
Endoscopic ultrasound was initially introduced in 1980s as a diagnostic modality combining echoendoscopes with radial scanning, which permitted reconstruction of cross-sectional images similar to computed tomography. Many studies showed that endogastric ultrasonography is more accurate than endoscopy or CT in evaluating the depth of invasion ( T category) and the involvement of lymph nodes (N category) in patients with gastric carcinoma. In addition to being very useful in tissue acquisition for diagnostic purposes, the principles behind endoscopic ultrasound-guided fine needle aspiration ( FNA) paved the way for the development of therapeutic endoscopic ultrasound, which improve the prognosis of patients with gastric cancer.
3.Investigation of human leukocyte antigen B27 between Uygur and Han nationality in Wrumqi region
Weiyi ZHOU ; Zhongli YANG ; Zhiwei LI
Chinese Journal of Laboratory Medicine 2003;0(11):-
60 years old,the positive rate of Han was higher than that of Uygur (?2=10.61 ?2=7.46,all P
4.Clinical significance of serum interleukin-6,8,18 in patients with lung cancer
Zhiwei ZHOU ; Haishan MO ; Hui LIANG
Cancer Research and Clinic 2006;0(11):-
Objective To study the relationships between serum interleukin-6, 8, 18 and the development, metastasis, curative effect and prognosis of lung cancer. Methods The serum interleukin-6, 8, 18 in 56 cases patients with lung cancer,18 cases patients with phthisis were determined by ELISA method before and after treatment, and 40 cases health people were control. Results The serum interleukin-6, 8, 18 level of patients with lung cancer was significantly higher than that in control groups and the patients with phthisis(P 0.05). Conclusion The serum interleukin-6, 8, 18 levels could reflected occurrence, development, metastasis and curative effect of the lung cancer in a certain extent, so it was importance for diagnosis, treatment and prognosis of lung cancer to combine examination IL-6, 8, 18.
5.The role of ATP-ubiquitin-proteasome pathway in the degradation of skeletal muscle protein during cancer cachexia
Wei ZHOU ; Zhiwei JIANG ; Jieshou LI ;
Parenteral & Enteral Nutrition 1997;0(04):-
The progressive loss of skeletal muscle protein observed in cancer cachexia may have a negative impact on both the quality of life and the survival time of patients. In recent years, accumulating evidences suggest that the ATP ubiquitin proteasome pathway may be crucial in muscle cachexia. The review is mainly about the role of the ATP ubiquitin proteasome pathway in the degration of skeletal muscle protein during cancer cachexia.
6.A study on the relationship between visual acuity and the latency and spatial fequency of P100 of pattern reversal visual evoked potentials in a view of forensic science
Shengyan LI ; Zhiwei ZHANG ; Xiaorong ZHOU
Chinese Journal of Forensic Medicine 1986;0(01):-
Objective To investigate the relationship between the parameter of P100 elicited by pattern stimuli, spatial frequency and visual acuity in the posttraumatic eyes. Methods 81 eyes sustained blunt injury in outpatients were enrolled from West China Hospital, Sichuan University. The control group was composed of 199 eyes without disease or trauma. Different P100 wave including amplitude and latency were recorded in each eye stimulated by reversal pattern with 5 - sized checkerboards. The data were processed by SPSS to describe the relationship between the visual acuity and the parameter of P100 wave. A linear and regression analysis was done in the statistic procedure. Results There was a high correlation between spatial frequency ( X) and the log visual acuity ( Y). Regression equations were deduced for evaluating the visual acuity. There was a correlation between the latency of P100 wave (X) and the log visual acuity (Y) in all the examined eyes. Conclusion The established regression equations can be used to evaluate the visual acuity as an accurate and objective method. There is a promising future of its application in the forensic clinical authentication of visual function.
7.Interventional drainage through sinus tracts for the treatment of postoperative abdominal abscess
Shouwang CAI ; Zhiwei LIU ; Ningxin ZHOU
Medical Journal of Chinese People's Liberation Army 2001;0(09):-
Objective To explore a new way to drain a postoperative abdominal abscess. Method Drainage catheter and sinography were employed to locate the site of the abscess, and a 10.2F~16F catheter with single or double lumen was inserted into the abscess by interventional technique. Result A 100% success was obtained for the 15 patients with 18 abscesses by inserting the drainage catheters, and all the abscesses were cured 7~65 days after drainage. Conclusions Compared with the surgical or percutaneous drainage, the present method is less traumatic, safer, more economical and effective, and it could be applies to all kinds of postoperative intraperitoneal abscesses which could not been drained adequately or with formation of sinus because of displacement of drainage tube.
8.The changes of CD cells in splenic tissue in patients with portal hypertension
Hongbo WANG ; Ningxin ZHOU ; Zhiwei LI
Journal of Chinese Physician 2000;0(12):-
Objective To investigate the changes of CD cells in splenic tissue in patients with portal hypertension(PHT) accompanied by hypersplenism to explore the features of immunological function in patients with PHT.Methods The resected splenic tissue was made into paraffin sections for the detection of number and distribution of CD_3~+,CD_8~+,CD_(20)~+ and CD_(68)~+ cells,with the control of those in healthy individuals.Results The numbers of CD_3~+,CD_8~+,CD_(20)~+ and CD_(68)~+ cells remarkably decreased in patients with PHT accompanied by hypersplenism compared with those in normal controls.In normal controls,the CD_(68)~+ cells mainly existed in splenic lymphocyte nodules and red pulp(RP),and in patients with PHT,they existed in splenic lymphocyte nodules and periarterial lymphatic sheath(PALS).Compared with the normal controls,the numbers of CD_(68)~+ in splenic lymphocyte nodules,red pulp and marginal zone(MZ) decreased in patients with PHT.Conclusion The number and distribution of CD cells are changed in patients with PHT accompanied by hypersplenism.With splenectomy,the immunological function may be improved and the abnormalities in routine blood parameters and liver function be corrected.However,the immunological indexes detected in the study can not completely show the systematic immunological function of the patients with PHT accompanied by hypersplenism.Thus we should conduct a long-term follow-up study on immunological function in these patients.
9.Expression of E-selectin and P-selectin in nodular vasculitis lesions
Mei CAI ; Danqi DENG ; Xiaohong ZHOU ; Zhiwei YUAN ; Ping FU
Chinese Journal of Dermatology 2011;44(6):415-418
Objective To estimate the significance of E-selectin and P-selectin in nodular vasculitis.Methods The EnVision two-step method was used to measure the expression of E-selectin and P-selectin in skin samples from the lesions of 70 patients with nodular vasculitis and normal skin of 24 human controls. The differences between the patients and controls in the expression of E-selectin and P-selectin and relationship between their expression levels in nodular vasculitis lesions were assessed. Results The expression of E-selectin was detected in all the specimens of nodular vasculitis, and most of the expression level was moderately intensive (++); while E-selectin was absent in all of the control specimens. All the specimens of nodular vasculitis stained postivive for P-selectin, which was strongly (+++) expressed in most of the specimens; while only 2 control specimens stained weakly positive for P-selectin. A significant difference was observed in the expression of E-selectin and P-selectin between the specimens from the patients and controls (both P< 0.01), but not among specimens from patients at different ages and between specimens from female and male patients (all P > 0.05). In addition, the expression of E-selectin and P-selectin was well correlated with each other in lesions of nodular vasculitis (P < 0.01). Conclusions The expression of E-selectin and P-selectin is correlated with each other in lesions of acute nodular vasculitis, and is associated with the development of nodular vasculitis.
10.Meta analysis of 95 patients with Ménétrier disease in China
Ye LIU ; Zhiwei XIA ; Zhiqiang SONG ; Zhigang DING ; Liya ZHOU
Chinese Journal of Digestion 2009;29(12):816-820
Objective To summarize the clinical features, diagnosis and treatment of Ménétrier disease in China. Methods A systematic review of Ménétrier disease in China was performed. Four electronic databases were searched from 1993 to 2008 including CNKI and Wanfang seeking studies about pathologically performed Ménétrier disease. Results Data of 95 patients with Ménétrier disease from 62 studies was included. There were 74 males and 21 females. The mean age of onset in adults was (47.4± 5.3) years . The process of the disease was longer in male individuals that in female individals (47.5 months vs. 13.7 months, P<0.05). The main symptoms included abdominal pain (76.8%), weight loss (42.1%), anorexia (40.0%) and edema of lower extremities (36.8%), etc.Hypoproteinemia was accounted for 71.6 % and most of the patients had hypochlorhydria. The typical giant hyperplastic gastric fold was found in 88.4 % of the patients under endoscopy. The diffuse type was in predominance and mainly involved the greater curve of the stomach (55.3 %). Whereas 5.3 patients were accompanied with gastric cancer. The misdiagnostic rate of the disease was 31. 6%,which accounted for 50% in surgically treated patients. Conclusions In China, the Ménétrier disease is predominant in middle-aged males, and the process is longer in males than in females. Misdiagnosis is related to existence of weight loss and hypoproteinemia. Most of the patients with Ménétrier disease have a good prognosis even the disease process is long.