1.Risk and Risk Control of Strain Medical Equipments
Zhirong XU ; Ting XU ; Shubo YANG
Chinese Medical Equipment Journal 2003;0(11):-
Pressure vessel is used in medical organization as a kind of special medical equipment. It's easy to cause injury when improperly used. By analyzing technical performance, product security, accident threat that weakness element of MTF is pointed out and some suggestions of prevention accidents are produced.
2.Effects of hypoxia-inducible factor-1α on the expression of heat shock proteins 90, Caspase 3 and Caspase 9 after cerebral ischemia-reperfusion
Zhirong HUI ; Tao TAO ; Jian XU
Chinese Journal of Geriatrics 2016;35(3):334-337
Hypoxia-inducible factor-1α (HIF-1α)is a transcription factor that acts as a master regulator of gene expression induced by low oxygen conditions.HIF-1α is the most sensitive indicator of hypoxia and can be activated by systemic hypoxia,cerebral hemisphere ischemia and cerebral focal ischemia.HIF-1 expression can be induced by hypoxic-ischemic damage after cerebral infarction and exert its effects on hypoxia-inducible downstream genes,thus protecting hypoxic tissues and cells under hypoxic conditions via regulating the expression of its downstream target genes.This article reviews the expression of HIF-1α and its downstream target genes in acute cerebral ischemia,in order to provide a theoretical basis for gene therapy.
3.Fuzzy evaluation for independent developing ability of civil medical equipment
Zhirong XU ; Yi ZHU ; Shubo YANG
Chinese Medical Equipment Journal 2004;0(09):-
As the base for the healthy development of civil medical equipment industry,the independent developing ability has attracted extensive attention.Firstly,medical equipment enterprises were divided into 5 modes according to their independent developing ability.Then the fuzzy evaluation method was utilized to evaluate them so as to correctly know the independent developing ability of medical equipment industry in our country.The evaluation shows that the brand value of the civil medical equipment is generally low.
4.Zero-line Automatic Calibration and Application for the Intelligent Medical Instrument
Zhirong XU ; Yi ZHU ; Xingyun RUAN
Chinese Medical Equipment Journal 2009;30(7):104-105
The intelligent level of the modern medical equipments is higher than before and the automatic calibration circuits are largely used. The control circuit of the intelligent equipments is quite complicated and its working modes have been simplified to four-terminal or double terminal nets. The intelligent medical equipments such as CT, MRI, DR, PET/ CT have more chances to have some "soft" errors that are usually related to the zero-line calibration. In actual use, it can be noticed and performed, and the detecting and servicing for the medical equipments can be much easier than before.
5.Value of combination of three-vessel views in ultrasound diagnosis of fetal aortic arch and pulmonary arterial branch anomalies
Yan XU ; Lianli JIE ; Zhirong JIANG ; Xiang GAO ; Jian CHENG
Chinese Journal of Ultrasonography 2015;(5):398-401
Objective To evaluate the role of combination of three-vessel views in ultrasound diagnosis of fetal aortic arch and pulmonary arterial branch anomalies.Methods The data of 66 cases of fetal aortic arch and pulmonary arterial branch anomalies were retrospectively analysed,including echocardiographic data,autopsy and operation records and postnatal follow-up results.Echocardiogaphic features and display frequencies on three vessels and trachea view(3VT),three vessels view(3VV)and three vessels and pulmonary arterial branches view(3VP)were summarized.Results There were 52 cases of aortic arch abnormalities,including 32 cases of right aortic arch with left ductus arteriosus,4 cases of double aortic arch,7 cases of aberrant right subclavian artery,6 cases of coarctation of aorta and 3 cases of interruption of aortic arch.Fourteen cases were diagnosed pulmonary aterial branch abnormalities,including 1 0 cases of crossed pulmonary arteries,2 cases of anomalous origin of left pulmonary artery from aortic arch and 2 cases of pulmonary artery sling.The display frequencies of fetal aortic arch and pulmonary arterial branch anomalies on 3VT,3VV and 3VP were 80.3%,19.7% and 39.4%.Conclusions The combination of three-vessel views is of great value in prenatal diagnosis of fetal aortic arch and pulmonary arterial branch anomalies.
6.Effects of erythropoietin on nestin expression in neural stem cells of neonatal rats with hypoxia-ischemia brain damage
Hong JIANG ; Feng XU ; Chunqing ZHOU ; Xianghong LI ; Zhirong SHU
Chinese Journal of Tissue Engineering Research 2010;14(36):6837-6840
BACKGROUND: Nestin is a specific antigen of neural stem cells which widely expressed in lesion of nervous system and brain regeneration.Thus,nestin expression is commonly used to assess whether lesion or damage of the nervous system can promote neural regeneration.OBJECTIVE: To investigate the effects of erythropoietin(EPO)on nestin expression in neural stem cells after hypoxia-ischemia brain damage(HIBD)in neonatal rats from the angles of neural regeneration and activation of neural stem cells.METHODS: HIBD model was established by ligation of the right common carotid artery along with 2-hour 8% hypoxia exposure in neonatal rats.The control group was not subjected to hypoxia-ischemia,and the right common carotid artery was dissociated.The treatment group received an intraperitoneal injection of recombinant human erythropoietin(rh-Epo,5 000 IU/kg)once a day for three days after hypoxia/ischemia,while the two other groups intraperitoneally received normal saline at the same time.In each group,rats were randomly executed immediately,at 4,7,14 days after operation(n = 8).The nestin expression in hippocampal dentate gyrus region was examined by immunohistochemical staining and image quantitative analysis respectively.RESULTS AND CONCLUSION: The number of nestin-positive cells was significantly increased in HIBD group compared to control group at all time points(P < 0.05),and it was also significantly increased in treatment group than the other two groups at all time points(P < 0.05).The numbers of nestin-positive cells in hippocampal dentate gyrus region were significantly increased,and peaked on day 7 after operation in the three groups.The results showed that exogenous rh-Epo could enhance the expression of nestin in hippocampal dentate gyrus region of neonatal rats with HIBD,and promote the proliferation of neural stem cells,rh-Epo plays an important role in the regeneration and repair of neurocytes damaged by hypoxia-ischemia.
7.Working mode conversion for skill improvement of technicians in medical engineering
Xingyun RUAN ; Liangcai ZHANG ; Zhirong XU ; Rongjun WANG
Chinese Medical Equipment Journal 2004;0(09):-
The quality of technicians is the dominate factor to determine the level of medical engineering section.The key to improving technical skills is to do basic jobs.During the Tenth Five-Year-Plan,we not only did many basic jobs and research works in science but did a lot of revolutions in order to accelerate the development of medical engineering and improve the working quality.Compared with the past,we have made great progress and development in standardized management,technology support,technician education,scientific researches,studies,technology level,the quality of service,etc.
8.Method of electron tomography three-dimensional reconstruction
Jing LI ; Xingyun RUAN ; Zhirong XU ; Rongjun WANG
Chinese Medical Equipment Journal 2003;0(11):-
This paper introduces the method of electron tomography three-dimensional reconstruction,which is widely applied in structural biology field and summarizes its advantages and disadvantages.The aim is to provide a reference for the application of the method.
9.Research of GPS for highway ambulances and vehicular medical power
Yi ZHU ; Xingyun RUAN ; Zhirong XU ; Zhenzhou WANG
Chinese Medical Equipment Journal 1989;0(01):-
Ambulance is a kind of new medical technique vehicle along with the development of medical science.Many countries are developing new ambulances in order to satisfy the demand of the emergency highway accident rescue.The GPS communication system and the vehicular medical power design are the most important parts of the ambulances for their complicated technology.This article discusses these two problems.
10.Quality Control Methods for Important Indexes of X-ray Generators
Yi ZHU ; Xingyun RUAN ; Liangcai ZHANG ; Zhirong XU ; Zhenzhou WANG
Chinese Medical Equipment Journal 1989;0(02):-
The quality control methods are the important to improve the exactness of diagnses and the effectivity of treatment.X-ray imaging quality is an important factor in improving the X-ray diagnosis effect.To serve this purpose,medical engineering personnel should do the X-ray quality control regularly to keep every parameter in accordance with national standards and demands.The quality control methods for several important indexes of X-ray generators are also discussed.[Chinese Medical Equipment Journal,2008,29(2):99-101]