1.Risk and Risk Control of Strain Medical Equipments
Zhirong XU ; Ting XU ; Shubo YANG
Chinese Medical Equipment Journal 2003;0(11):-
Pressure vessel is used in medical organization as a kind of special medical equipment. It's easy to cause injury when improperly used. By analyzing technical performance, product security, accident threat that weakness element of MTF is pointed out and some suggestions of prevention accidents are produced.
2.Zero-line Automatic Calibration and Application for the Intelligent Medical Instrument
Zhirong XU ; Yi ZHU ; Xingyun RUAN
Chinese Medical Equipment Journal 2009;30(7):104-105
The intelligent level of the modern medical equipments is higher than before and the automatic calibration circuits are largely used. The control circuit of the intelligent equipments is quite complicated and its working modes have been simplified to four-terminal or double terminal nets. The intelligent medical equipments such as CT, MRI, DR, PET/ CT have more chances to have some "soft" errors that are usually related to the zero-line calibration. In actual use, it can be noticed and performed, and the detecting and servicing for the medical equipments can be much easier than before.
3.Fuzzy evaluation for independent developing ability of civil medical equipment
Zhirong XU ; Yi ZHU ; Shubo YANG
Chinese Medical Equipment Journal 2004;0(09):-
As the base for the healthy development of civil medical equipment industry,the independent developing ability has attracted extensive attention.Firstly,medical equipment enterprises were divided into 5 modes according to their independent developing ability.Then the fuzzy evaluation method was utilized to evaluate them so as to correctly know the independent developing ability of medical equipment industry in our country.The evaluation shows that the brand value of the civil medical equipment is generally low.
4.Effects of hypoxia-inducible factor-1α on the expression of heat shock proteins 90, Caspase 3 and Caspase 9 after cerebral ischemia-reperfusion
Zhirong HUI ; Tao TAO ; Jian XU
Chinese Journal of Geriatrics 2016;35(3):334-337
Hypoxia-inducible factor-1α (HIF-1α)is a transcription factor that acts as a master regulator of gene expression induced by low oxygen conditions.HIF-1α is the most sensitive indicator of hypoxia and can be activated by systemic hypoxia,cerebral hemisphere ischemia and cerebral focal ischemia.HIF-1 expression can be induced by hypoxic-ischemic damage after cerebral infarction and exert its effects on hypoxia-inducible downstream genes,thus protecting hypoxic tissues and cells under hypoxic conditions via regulating the expression of its downstream target genes.This article reviews the expression of HIF-1α and its downstream target genes in acute cerebral ischemia,in order to provide a theoretical basis for gene therapy.
5.Orthogonal test for effect of water and alcohol extracting process to anthraquinone content in Rhubarb
Yuan HUANG ; Xiongliang XU ; Zhirong ZHANG ; Jing ZOU ; Li CHEN ;
Chinese Traditional Patent Medicine 1992;0(04):-
Objective: To study the effect of water extracting and alcohol extracting process to anthraquinone content in Rhubarb. Methods: Choosing water and different concentration of alcohol as the solvent, the effect of permeating time, the extracting time, the degree of extracting, the amount of solvent and concentration of alcohol to total, conjugated, and deoxidized anthraquinone content were determined by orthogonal test. Results: Using water as the solvent, the degree of extracting is the significant factors to total anthraquinore with ( P
6.Vertical mammaplasty for correction of severe breast ptosis
Shengkang LUO ; Zhongshen SUN ; Haibin WANG ; Xiang XU ; Zhirong TANG
Chinese Journal of Medical Aesthetics and Cosmetology 2008;14(5):289-292
Objective To introduce and evaluate an improved technique of vertical mammaplasty for correction of severe breast ptosis. Methods Vertical mammaplasty that was first reported by Ma-deleine Lejour in Brussels is a technique that uses adjustable markings, an upper pedicle for the areola, and a central breast reduction with lower skin undermining. To shorten vertical scar, it was important to locate new nipple position and move up new inframammary fold. The shape of the breast was crea-ted by suturing the gland and did not rely on the skin. No scar was produced in submammary fold. Re-sults 36 cases were treated with vertical mammaplasty in our department since August 1999. The shape of the new breast was satisfactory in all patients after 3-24 months following-up. Areora necro-sis was not found in all the cases. Conclusion The vertical mammaplasty is an optical technique for correction of severe breast ptosis, Stable results are produced because the gland is strongly sutured.
7.The apoptosis of bovine lens epithelial cells induced by proteasome inhibitor MG132.
Xing, XING ; Yizhen, HU ; Yang, CAO ; Zhirong, XU
Journal of Huazhong University of Science and Technology (Medical Sciences) 2008;28(4):469-71
To investigate the effect of proteasome inhibitor MG132 on the apoptosis of bovine lens epithelial cells (BLECs), the cells were treated with MG132 at different concentrations for12, 24 and 36 h. The cell viability was analyzed by MTT assay and the effect of MG132 on the apoptosis of BLECs was assessed by flow cytometry (FCM). The results showed that after treatment for the same period, the inhibitory effect of MG132 on BLECs proliferation was enhanced with the increment of the concentration of MG132 (0, 2, 5, 10, mumol/L) (P<0.05). The 50% inhibiting concentration (IC(50)) was 2.03 mumol/L when the BLECs were treated with MG132 for 36 h. MG132 also induced the apoptosis of BLECs obviously. FCM showed that the apoptosis index of the cells treated by MG132 at 2 mumol/L for 12 h was (20.24+/-1.51)%, and that of the control was (0.98+/-0.20)% respectively (P<0.01, n=3). It was concluded that MG132 could lead to apoptosis of BLECs. The decrease of proteasome activity may play an important role in the formation and development of cataract.
8.Orthogonal test for optimization of quercetin extracting procedure from bud of Sophora japonica
Qin HE ; Xiongliang XU ; Zunhong KE ; Zhirong ZHANG ; Lil LI
Chinese Traditional and Herbal Drugs 1994;0(05):-
Object To select the optimum extracting procedure for quercetin from bud of Sophora japonica L. Methods The optimum extracting procedure was selected with the content and extraction effeciency of quercetin from bud of S. japonica by orthogonal test design. Results The optimum extracting procedure was determined with 10 times of 0.05% sodium hydroxide decocting 20 min and 4 times, adjusting pH value to 6, hydrolyzing with 10 times of 4% sulfuric acid for 1 h after precipitated. Conclusion The optimum extracting procedure increased the content and extraction efficiency of quercetin from bud of S. japonica.