To investigate the phenotype characteristics of peripheral blood lymphocytes(PBL)grown in the presence of IL 12 and IL 2. CD2,CD3,CD8,CD28, CD19 and NK were detected using immunofluorescence and flow cytometry. The phenotype of PBL showed significant changes after being cultured 72h with IL 12 and IL 2 respectively.IL 12 mainly increased CD2( P