1.Role of new emergency mode "Green track" in treatment of traffic injuries
Chinese Journal of Trauma 2010;26(7):617-619
Objective To explore the role of new emergency mode "Green track" in treatment on traffic injuries. Methods The data of 2 947 patients with traffic injuries rescued by prehospital emergency "green track" and inhospital emergency treatment from March 1998 to January 2009 were retrospectively studied in aspects of prehospital and inhospital treatment methods and their results. Results Of all patients, 2 089 patients were treated surgically and 858 patients treated conservatively, in which 2 736 patients (92.8%) were cured but 211 (7.2%) died, with mortality rate of 7.2%. Head, face and limbs were the main injury parts. Of all, 1 874 patients (63.6% ) were admitted into the hospital within one hour after injury. Conclusions The new emergency mode "Green track" , either prehospital or inhospital, can markedly improve success rate of treatment for traffic injuries, increase survival rate and is of importance to be clinically applied.
2.Clinical investigation on the correlation between lower urinary tract infection and cystitis glandularis.
Zhiqiang, CHEN ; Zhangqun, YE ; Wei, ZENG
Journal of Huazhong University of Science and Technology (Medical Sciences) 2004;24(3):303-4
In order to study the association between lower urinary tract infection and cystitis glandularis (CG), 120 cases of CG were diagnosed by cystoscopic biopsy in the suspicious foci of the bladder. Among them, 72 cases were subjected to bacterial counting culture of urine and microscopic examination of urinary sediment, and 60 cases to fluorescence quantitative polymerase chain reaction (FQ-PCR) assay to detect HPV, CMV and HSV DNA in urine samples. In the 72 cases of CG, the positive rate of bacterial counting culture of urine was 15.3% (11/72), and gray zone rate was 18.1% (13/72). 31.9% (23/72) patients were positive in bacterioscopy of urinary sediment. There was statistically significant difference as compared with the control group (P<0.01). Only 4 of 60 urine samples were positive by FQ-PCR in detection of the three viruses mentioned above with the positive rate being 6.67%. Compared with the control group, there was no significant difference (P>0.05). It was concluded that the genesis of CG was closely correlated with the chronic lower urinary tract infection, especially caused by Esch coli.
Cystitis/etiology
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Cystitis/microbiology
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Cystitis/*pathology
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*Escherichia coli Infections
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Metaplasia
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Urinary Bladder/microbiology
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Urinary Bladder/*pathology
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Urinary Tract Infections/complications
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Urinary Tract Infections/*microbiology
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Urinary Tract Infections/pathology
3.Empirical study of autogenous dermal grafts in the prevention of epidoral fiSrosis and adhesions
Mushun HE ; Yuedong ZENG ; Zhiqiang QU
Chinese Journal of Orthopaedics 2009;29(8):765-770
Objective To investigate the ability of auto-dermis grafts in the prevention of epidural fibrosis and adhesions, and provide reference for clinical application. Methods Five Tibet mini-pigs were used and laminectomy was performed in lumbar 2 and 4 segment. Dura was exposed and covered with auto-genous dermis grafts in lumbar 2 (the experimental group), without grafts in lumbar 4 (the autogeoous blank group). The specimens were observed grossly and histologically at 2, 4, 6, 8 and 10 weeks postoperatively. Epidural scar amount and adhere range was evaluated by modified Robertson scoring method and analyzed by SPSS 13.0. No sear and adhesion, 0 point; small amount scar and light-range adhesion, 1 point; medium sear and midrange adhesion, 2 pionts; bulk scar ang high-range adhesion, 3 pionts. Results All grafted dermis survived and thicken obviously than dermis in body surface (P< 0.05). Hair growth, sebaceous gland cyst and sweat cystogenesis were not observed. A larvaceous dissection abruption plane, little cicatricial tis-sue and adhesions rarefaction between dermis and dura were observed in the experimental group. Massive ei-catricial tissue from erector spinae filled in cavitas epiduralis was observed and dura was separated difficult-ly from cicatricial tissue in the autogeous blank group. Epidural scar amount and adhesion range in the ex-perimental group was significantly lower than the blank group (P< 0.05). Conclusion Dermis is a kind of favourable biomaterial with restraining cicatrisation and isolation barrier. Autogenous dermis grafts has the best effect on preventing peridural cicatrisation and adhesion after laminectomy.
4.CLINICAL EFFECT OF SOCIALIZATION MANAGEMENT OF FAMILY-BASED COMMUNI-TY ON PATIENTS WITH HYPERTENSION
Haibo WEN ; Zhiqiang ZENG ; Yanjin LING
Modern Hospital 2015;(3):154-156
Objective To explore the curative effect of family -based socialization management on patients with hypertension in community .Methods A total of 116 patients with hypertension were randomly divided into ob-servation group and control group , 58 patients in each group .Both groups received conventional drug treatment .The control group was given routine chronic disease management and the observation group implemented social manage -ment(patients, families, doctors).Blood pressure(BP),lifestyle and psychological condition were evaluated , and the serum triglyceride ( TG) , low density lipoprotein ( LDL) and homocysteic acid ( Hcy) were detected after one year . Results Blood pressure of patients was dropped significantly in the two groups , as compared with the control group . The BP of patients in the observation group was declined more obviously , the BP up to standard rates , control rates and treatment compliance were raised , the mode of life and mental status were improved obviously , and the serum contents of TG, LDL and Hcy were decreased significantly (p<0.05).Conclusion The use of hypotensorscombined with fam-ily-based social management can effectively help patients to control their blood pressure , raise treatment compli-ance, establish a healthy life style and improve their mental status .The mode is worth of spreading in community .
5.Significance and expression of S100A9 and NMP238 in cervical carcinoma tissues with different concurrent chemoradiotherapy sensitivities
Hong ZHU ; Shan ZENG ; Liang ZENG ; Xuewei WANG ; Zhiqiang XIAO
Journal of Central South University(Medical Sciences) 2010;35(1):45-51
Objective To determine the significance and expression of S100A9 and NMP238 in cervical carcinoma with different concurrent chemoradiotherapy sensitivities. Methods Fresh carcinoma tissues were collected from untreated cervical carcinoma patients and preserved at -80 ℃. The tissues were classified into 2 groups:a high sensitivity group (HS) and a low sensitivity group(LS) according to their response to concurrent chemoradiotherapy. Protein was separated by 2-dimensional gel electrophoresis (2-DE). Peptide mass fingerprintings (PMF) were acquired by matrix assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS) and the proteins were identified by data searching in the Mascot-database. Differential expressed proteins were assayed by Western blot and immunohistochemistry.Results Most of the gels were clear and were successfully and reproductively analyzed. Intensity and rate of S100A9 expression were higher in the HS group than in the LS group,and those of NMP238 expression were higher in the LS group than in the HS group. Conclusion S100A9 and NMP238 expression is associated with concurrent chemoradiotherapy sensitivity in cervical carcinoma.
6.Comprehensive rhinoplasty with transplantation of autologous costal cartilage
Gao ZENG ; Zhiqiang XUE ; Zhanwei GAO ; Yanwen QI ; Haihuan MA
Chinese Journal of Medical Aesthetics and Cosmetology 2013;19(6):407-410
Objective To explore the comprehensive approach of rhinoplasty using autologous costal cartilage,and to observe the outcome and summarize the possible complications.Methods A 6-7 cm long costal cartilage was taken out mostly from the 6th or 7th rib and then divided into several parts and shapes.A lancet shaped piece was used for dorsal augmentation,several cartilage bars for collumellar elevation and nasal tip elongation.Comprehensive structural rhinoplasty was then done with open rhinoplasty incision.Results 52 patients were treated with this method and satisfying aesthetic contouring of the nasal tip and dorsum was achieved.Among these patients,no such complications as implant extrution or dislocation,cartilage distortion,pneumothorax,hemothorax,infection or hemotoma were observed.The scar on the donor site was not obvius.Conclusions Costal cartilage can meet the demands of patients who consider prosthesis as an unacceptable option.For secondary revision rhinoplasties,costal cartilage provides sufficient materials to ensure a promising outcome with lower risk of infection and other complications.
7.Pre-administration of Ganoderma lucidum spore reduces incidence of neural tube defects induced by retinoic acid in pregnant mice
Wei ZHANG ; Yuanshan ZENG ; Yi XIONG ; Suijun CHEN ; Zhiqiang ZHONG
Journal of Integrative Medicine 2006;4(4):368-73
OBJECTIVE: To explore whether pre-administration of Ganoderma lucidum spore (GASP) can reduce incidence of neural tube defects (NTDs) induced by all-trans retinoic acid (ATRA) in pregnant mice. METHODS: Twenty pregnant mice were randomly divided into four groups: normal control group, solvent-treated group, ATRA-induced group, and GASP-treated plus ATRA-induced group. GASP solution, which was prepared with solvent (sodium carboxymethyl cellulose), was fed to the pregnant mice in the GASP-treated plus ATRA-induced group twice a day from embryo (E) 0 d to E10.5 d. The same dose of solvent was given to the pregnant mice in the solvent-treated group. At E7.75 d, ATRA (50 mg/kg) was given to the pregnant mice in both ATRA-induced group and GASP-treated plus ATRA-induced group for single time. Embryos were sampled from pregnant mice at E10.5 d. Then the incidence rate of NTDs in mouse embryo was calculated and the crown-rump length of mouse embryo was measured. The positive rate of nestin expression and the distribution of cell cycle of embryonic neural tube neuroepithelial cells were detected by histochemical staining technique and flow cytometry respectively. Reverse transcription-polymerase chain reaction method was used to detect the gene expressions of cyclin-dependent protein kinase 2 (Cdk2) and Cdk4 mRNAs. RESULTS: The incidence rates of NTDs in mouse embryos in the ATRA-induced group and the GASP-treated plus ATRA-induced group were 79.41% and 21.67% respectively, while the crown-rump length of mouse embryos in these two groups were (3.62+/-1.27) mm and (5.84+/-0.92) mm respectively. The positive rate of nestin expression in embryonic neural tube neuroepithelial cells of mouse embryo at E10.5 d in the ATRA-induced group was 32.44%, while that in the GASP-treated plus ATRA-induced group was 77.65%. The cell cycle of embryonic neural tube neuroepithelial cells was obviously arrested at G(0)/G(1) phase in the ATRA-induced group as compared with that in the GASP-treated plus ATRA-induced group. The Cdk4 mRNA was transcripted at a high level in embryonic neural tube in the GASP-treated plus ATRA-induced group, but the Cdk2 mRNA was not detected in this group. CONCLUSION: Pre-administration of GASP can reduce the incidence of NTDs induced by ATRA in pregnant mice.
8.Imaging Features of Solitary Enchondroma
Zhiqiang OU ; Xuwen ZENG ; Dekun DU ; Minzhi ZHONG
Journal of Practical Radiology 1991;0(03):-
Objective To discuss the clinic and imaging features of solitary enchondroma.Methods Radiography,CT and MRI were performed in 11 cases of solitary enchondroma confirmed by pathology.The imaging findings were retrospectively analysed.Results The tumors in 11 cases localized in metacarpal bone in 3, in bones of fingers in 4, in shaft of humerus in one,in metaphysis of femur in 2 and in metaphysis of tibia in one.Plain radiography showed typical radiographic features including a well defined central lucency in the diaphysis of the metacarpal bones and bones of fingers with calcifications inside the lesions and lobulated contour,the cortex was thinned and cortical expansion also might occur.The lesions appeared as soft tissue density with stippling calcification on CT,low signal intensity on T1WI and mixed mainly high signal intensity on T2WI.A low signal zone around the lesion could be seen on T2WI in one case.Conclusion The qualitative and differential diagnosis of solitary enchondroma can be made mostly by imaging examination.
9.Research advances in modern operation power device of skull bore
Yijun GUO ; Shaoxi CAI ; Zhiqiang ZHAO ; Chuisheng ZENG ; Wei WANG
Chinese Medical Equipment Journal 1989;0(04):-
Skull bore device has an important role in neurosurgery.This review is a summary of the development,current research status and advances of skull bore.The electrical operation power device is the emphasis in the review.It is important to develop newly operation power devices for human health.
10.Aesthetic correction of septal deviation with nasal deformify
Gao ZENG ; Haihuan MA ; Zhiqiang XUE ; Xiaogen HU
Chinese Journal of Medical Aesthetics and Cosmetology 2011;17(4):257-259,265
Objectives To explore a comprehensive approach for the functional and aesthetic correction of septal deviation. Methods From Jan. 2007 to Dec. 2009, 48 patients with deviation of the frontier and ceiling border of the septal cartilage, 6 males, 42 females, average age of 26.5 years, were surgically treated with a comprehensive use of several techniques, such as septoplasty, reconstruction of septal support, precise osteotomies and nasal tip plasty. Results Functional improvement achieved in all the patients, contour satisfaction achieved in 91.7 % patients; 30 patients were very satisfied, and 14 satisfied with the outcome. Conclusions With the thorough understanding of surgical anatomy of the nose and the use of comprehensive surgical approach, satisfactory outcomes can be achieved both functionally and aesthetically in patients with septal deviation.