Objective To investigate the clinical outlook of hepatic stem cells and its relations with liver cancer. Methods The literatures of recent years on the studies of hepatic stem cells were reviewed. Results Liver cancer may consist of cells of various differentiation grades and it may result from the perodifferentiated hepatic stem cells or abnormal differentiated cells. Conclusion The hypothesis of hepatic stem cells has been identified extensively. Further study maybe helpful for revealing the origin, carcinogenesis of hepatic cancer, and may also be useful for the understanding of the mechanism of metastasis.

Objective To study the application of transurethral bipolar plasma kinetic vaporization of the distal ureterectomy in radical nephroureterectomy for renal pelvic or ureteral carcinoma. Methods A total of 6 patients with renal pelvic or ureteral carcinoma without involvement in ipsilateral distal ureter,ureteral orfice,and the bladder were included.Radical nephroureterectomy was performed by using transurethral bipolar plasma kinetic vaporization combined with either flank incision nephrectomy (5 patients) or retroperitoneal approach laparoscopic nephrectomy(1 patient). Results The operation was completed smoothly in the 6 patients with comparatively little blood loss.The operation time was 120~210 min(mean,150 min).Obturator nerve reflex happened in no patients during the operation.Postoperative bladder irrigation found no bleeding in the bladder.The time of indwelling the catheter was 7~9 d(mean,8 d).Hypogastralgia and fever occurred in 1 patient on the 5th postoperative day.And the patient was confirmed as having mild urinary extravasation and was given catheter indwelling for 5 days. Transuretheral cystography found no leakage and a full recovery of voiding function was achieved.Postoperative pathological findings showed negative margins in all the patients.One patient died of myocardial infarction 3 months after operation,while follow-up in the remaining 5 patients for 7~21 months(mean,16 months) showed no tumor recurrence. Conclusions Application of transurethral bipolar plasma kinetic vaporization of the distal ureterectomy is micro-invasive,with little hemorrhage and few complications.It is an effective assistant option in radical nephroureterectomy.

Ultrasound can be used to visually evaluate brain structure, estimate intracranial pressure, and identify the function of cerebrovascular autoregulation and the reactivity of cerebrovascular carbon dioxide.It can also be used in the diagnosis of cerebral vasospasm and systemic circulation evaluation.Critical care ultrasound can help clinicians identify the primary injury of neurological system, prevent and effectively manage the secondary injury through bedside, real-time, non-invasive evaluation and monitoring.It can guide the implementation and evaluate the curative effect of brain protection algorithm.

The molecular and cellular mechanisms of bone metastasis in prostate cancer remain unclear. Current researches focus on chemotaxis of tumor cells in bone metastasis, interactions between tumor cells and bone micro-environment as well as the vicious circle among tumor cells, osteoclasts, osteoblasts and bone matrix.

The malignant pleural mesothelioma is kind of tumor that has close contact with theasbestos to oncolytic,and its attack is very strong.Because the reasons of it iS not obviously and always be found in the middle of late period,the present treatment plan dosnt have a satisfied effect.However oncolytic herpes simplex viruses and obliging platinum induction to oncolyti herpes simplex viruses that generate the GADD34 protein may have the relative specificity to themesothelioma cancer cell,therefore is a prospect ive treatment plan.

Objective To observe the concentration change of 0.5% peracetic acid used as disinfectant in the indoor air. Methods KC-6D gas-sampler and ion chromatograph were employed and sampling interval time was 10-15 min, 7 samples were collected each time in both of the condition of closed and ventilated, the same experiment was repeated for 3 times. Results As the time went on, the concentration change of 0.5% peracetic acid in the indoor air increased from 6.24 mg/m3 to 20.72 mg/m3 in the condition of closed and decreased in the condition of ventilated from 6.92 mg/m3 to 3.36 mg/m3. Conclusion In a closed room of 20 m3, using 500 ml 0.5% peracetic acid, after 30 minutes of disinfection followed by 60 minutes of ventilation, the concentration of peracetic acid will be about 3.36 mg/m3 in the air of the room.

Ambulatory electrocardiogram (ECG) monitoring can effectively reduce the risk and death rate of patients with cardiovascular diseases (CVDs). The Body Sensor Network (BSN) based ECG monitoring is a new and efficien method to protect the CVDs patients. To meet the challenges of miniaturization, low power and high signal quality of the node, we proposed a novel 50 mmX 50 mmX 10 mm, 30 g wireless ECG node, which includes the single-chip an alog front-end AD8232, ultra-low power microprocessor MSP430F1611 and Bluetooth module HM-11. The ECG signal quality is guaranteed by the on-line digital filtering. The difference threshold algorithm results in accuracy of R-wave detection and heart rate. Experiments were carried out to test the node and the results showed that the pro posed node reached the design target, and it has great potential in application of wireless ECG monitoring.
Algorithms ; Cardiovascular Diseases ; diagnosis ; Electrocardiography, Ambulatory ; instrumentation ; Equipment Design ; Heart Rate ; Humans ; Wireless Technology ; instrumentation

Lung cancer has been widely known for its highest morbidity among all tumors in this world.Anti-sense neoclitide technology is a kind of widely-recognized gene therapy for its high efficiency and practical simplicity.This essay will briefly review principles of anti-sense neoclitide technology used in treatment of lung cancer and characteristics of this technology in gene therapy of lung cancer.

0.05).The operation was failed in 2 cases due to the displacement of the renal tube(re-puncture was performed) or massive hemorrhage from torn renal calices(the procedure was terminated,and the bleeding was controlled by compression and hemostat).One patient developed acute pulmonary edema after the operation and was cured by diuretic;4 cases showed postoperative fever;no serious complications occurred in this series.The stone-free rate in one session was 89.1%(49/55).The residual calculi were all cleared by a second operation combined with extracorporeal shock-wave lithotripsy.The patients were followed up for 3 to 12 months(mean,6 months),during which no recurrent case was found.ConclusionUreteroscopy is safe and effective for establishing renal channel in minimally invasive percutaneous nephrolithotomy.

Objective:To explore the mediating effect of belief in a just world and self-esteem on relationship between childhood abuse and subjective well-being in college students.Methods:Totally 929 college students[314 males and 615 females,aged 17 to 25 year,mean age (20 ± 3) year] from 4 universities of Harbin were assessed.The Childhood Trauma Questionnaire (CTQ-SF) was used to assess childhood abuse,the Satisfaction with Life Scale (SWLS) and the Affect Balance Scale (ABS) was used to assess subjective well-being,the Believe in a Just World Scale (BJW) was used to assess belief in a just word,and the Self-Esteem Scale (SES) was used to assess self-esteem.The Bootstrap was used to test the mediating effect of belief in a just world and self-esteem on relationship between childhood abuse and subjective well-being.Results:General belief in a just world,personal belief in a just world,self-esteem played an independent mediating effect respectively between childhood abuse and life satisfaction.The confidence interval from Bootstrap output were 95％ (-0.026--0.001),95％ (-0.141--0.058) and 95％ (-0.235--0.122).Personal belief in a just world and general belief in a just world played chain mediating effect between childhood abuse and life satisfaction (-0.059--0.004).Self-esteem played an independent mediating effect between childhood abuse and emotional balance (-0.308--0.181).Personal belief in a just world and general belief in a just world played chain mediating effect between childhood abuse and emotional balance (-0.046--0.001).Conclusion:Childhood abuse and subjective well-being of individuals,belief in a just world and self-esteem are related.Belief in a just world and self-esteem play mediating effect between childhood abuse and subjective well-being.