Assistive technology has been one of key words in the field of special education. It will also be new trend of special educational development. In the article, the authors firstly introduced the definition of assistive technology device and assistive technology service and discussed the relationship between assistive technology and educational technology, and special educational changes in technology and idea because of the use of assistive technology, at last, some suggestions to enhance the use of assistive technology were put forward.

Metallic cancellous screw is one of the fixation devices widely used for bone fractures. It has always been reported that many cases of internal fixation failed just because of screw loosening or pullout. The stability of fixation is associated with the pullout strength of screws. The pullout strength strongly depends on the geometrical design of the screw thread, the material and the insertion technique of the screw, and the bone mineral density of the insertion site of the screw.

Objective To address the expression correlation of ribosome-related genes in rat regeneration liver(RL) and those in liver tumor at transcriptional level.Methods Genes involved in ribosome biogenesis,assembly and function,as well as their expression changes in liver tumor,were obtained by online data collection and literature review,and their expression profiles in rat regenerating liver were detected by Rat Genome 230 2.0 array.Expression similarities and differences of the above genes were analyzed using statistical methods. Results A total of 75 genes were found to be RL-related.In regenerated liver and liver tumor,the expressions of 18 genes increased and 6 genes decreased,and no significant expression changes were found in 51 genes in liver tumor.Conclusion The expression profiles of the ribosome-related genes in regenerated liver cells and liver tumor cells have both similarities and differences,and the former exhibit properties of more gradualness and complexity.

Dopamine(DA) modulates diverse wake-related behaviors including movement,reward, and cognition.Dopaminergic neurons are located in the substantia nigra pars compacta and ventral tegmental area.There are five distinct DA receptors(R):D_1R,D_2R(D_(2S)R and D_(2L)R), D_3R,D_4R and D_5R in the central nervous system, in which D_1R and D_2R are majorly expressed. The affinity of D_2R for endogenous DA is significantly higher than that of D_1R.Re- cently,studies by pharmacological and gene knock-out animals revealed that dopamine D_2R is essential inmaintaining wakefulness.Here,we review the progress on roles of D_2R in sleep-wake regulation.

Aim To set up a highly effective and automatic mouse sleep-wake bioassay system,and evaluate the system through analysis of the somnogenic effects of L-stepholidine(SPD),targeting at dopamine D1/D2 receptors in mice.Methods The animals were housed in an insulated and soundproof recording chamber maintained at a constant temperature and humidity on an automatically controlled 12 h light/12 h dark cycle.The electroencephalogram and electromyogram were recorded continuously for 48 hours and analyzed by SleepSign software.Saline was administered ip to the mice at 21:00 on the first day,and SPD was given on the next day at the same hour.The vigilance state was analyzed based on the polygraphic recordings by the same software.Results The system has been demonstrated to be highly efficient and stable in recording and reliable in analyzing sleep-wake behavior in mice.With the aid of the sleep bioassay system,we found that SPD significantly increased the total time spent in sleep during dark period,and prolonged durations of non-rapid eye movement sleep episodes,with a concomitant reduction in amount and EEG power density of wakefulness.SPD rendered no effect on rapid eye movement sleep.Conclusion Through the reliable mouse sleep bioassay system,we found that SPD promotes non-rapid eye movement sleep but not rapid eye movement sleep in mice.

Objective To explore the CT appearance of thoracic lymphonodus in AIDS patients with immune reconstitution in-flammatory syndrome(IRIS)after highly active antiretroviral therapy (HAART).Methods The data of thoracic CT in 24 AIDS pa-tients after HAART with enlarged thoracic lymphonodus in IRIS were collected,and the chest CT appearance was analyzed.Results Of the 24 cases of AIDS patients with IRIS after HAART,1 9 cases were complicated with pulmonary tuberculosis,which includ-ed 5 cases with cervical tuberculous lymphadenitis,3 cases were co-infected with bacterium and fungi,1 case was infected by penicil-lium marneffei,1 case by pneumocystis carinii.The enlarged thoracic lymphonodus were primarily located in 4R region(20/24), secondly in 2R region(1 1/24)and 4L region(1 1/24),in which the density was uniform or non-uniform,edge clear or unclear,some parts of lymphonodus were fused together but not calcified.The minor axis of enlarged lymphonodus was 1 1.0-25.0 mm except X region,enhanced uniformly in 2 cases.Obstructive pneumonia and pulmonary consolidation were found in 2 cases with enlarged lym-phonodus,which were located in 10R region.Pleural effusion was found in 13 cases with greatest depth of about 22 mm,pericardial effusion was found in 5 cases with greatest depth of about 24 mm.Conclusion The enlarged thoracic lymphonodus in AIDS patients with IRIS affer HAART are mainly involved in the region of 4R,2R and 4L,with or without pleural effusion and pericardial effusion.

Objective:To observe the effects of Deoxyschisandrin on hemorrheology and coagulation function in ulcerative colitis (UC)mice.Methods:Trinitrobenzenesulfonic acid (TNBS)induced UC mice model was prepared.And then UC mice were randomly divided into model group,positive control group,high,medium,and low dose groups of deoxyschisandrin (80,40,20mg/kg),and in addition,a normal control group was set up.There were 10 mice in each group respectively.UC mice were intragastricly administrated with different concentration of deoxyschisandrin in medication group,or with equal volume distilled water in normal group or model group,respectively.The blood viscosity was determined by blood rheometer,and the bleeding time (BT)and the clotting time (CT)were also observed through the methods of tail cutting and blood coagulation in glass plates accordingly.Results:Compared with model group,the BT (P ＜ 0.01)and CT (P ＜ 0.05)were significantly prolonged,and the blood viscosity was decreased obviously (P ＜ 0.05) in UC mice after administrated with different concentration deoxyschisandfin for 14 days.And the effects in high dose group were strongest and similar to those in the positive group.Conclusions:Deoxyschisandrin can improve hemorrheology and coagulation function in UC mice.

Objective To investigate the survival status and related influencing factors of very low birth weight infants(VL-BWI) and very early preterm infants(VPI).Methods One hundred and forty-two very low birth weight and very preterm infants in our hospital from April 2012 to January 2016 and contemporaneous 140 non-low-birth-weight and non-very-preterm infants were selected.The survival status of newborns and long-term prognosis were compared.The low birth weight children and very preterm infants were divided into the death group and survival group according to the survival status and long-term prognosis.The clinical data in the two groups were performed the univariate and multivariate Logistic regression analysis.Results The incidence rate of poor prognosis had statistically significant difference among neonates with birth weight less than 1 500,1 500-2 500 and＞2 500 g(P＜0.05).The incidence rate of poor prognosis had statistically significant difference among neonates with the gestational age≤32 weeks,32-37 weeks and≥37 weeks(P＜0.05).The proportions of gestational age,birth weight and antenatal dexamethasone use in the death group were significantly lower than those in the survival group,while the proportions of maternal age,asphyxia,meconium aspiration,pregnancy induced hypertension and mechanical ventilation in the death group were significantly higher than those in the survival group,the difference between two groups was statistically significant(P＜0.05).The gestational age≤28 weeks,birth weight≤1 000 g and asphyxia were the independent risk factors affecting the survival status in very low birth weight infants and extremely preterm infants(P＜0.05).Conclusion In VLBWI and VPI the living status,and long-term prognosis are poor and prone to mental and movement disorders.

OBJECTIVE: To survey the prevalence of obstructive sleep apnea-hypopnea syndrome(OSAHS) in adults aged over 60 years in Dongying city,and analyze the risk factors and the extent of damage to the quality of life for the elderly to provide the basis for prevention and treatment of OSAHS people. METHOD: One thousand subjects were derived from a random cluster sampling in seven districts of Dongying city:they were asked to answer the questions from questionnaires. According to the questionnaire scoring, 100 subjects in high-risk group were selected randomly to make polysomnography monitoring for a whole night,so that the prevalence of the disease was calculated and the related risk factors were analyzed; elderly patients diagnosed with OSAHS were asked to assess the quality of life assessment questionnaire by face to face to understand the quality of life dimensions injury. RESULT: The actual number of completed surveys was 934, and the efficiency was 93.4%. The estimated prevalence of OSARS in elder people defined by apnea-hypopnea index (AHI ≥ 5) was 32.5%; Multivariate analysis revealed that age smoking, family snoring,neck circumference, waist circumference, and abnormality of the upper airway were respectively independent risk factors of OSAHS,and the abnormalities of the upper airway had the most obvious impact on AHI. The damage caused by OSAHS to the quality of life for elderly people followed their daily work life, social relationships, symptoms, alertness, emotional, general health, symptoms. CONCLUSION The estimated prevalences of OSAHS in elder people were high. Actively promoting good habits to older people, weight loss, early detection and correct upper airway abnormalities may reduce the estimated prevalence of OSAHS. In the treatment process, the patient's physician should pay attention to their emotional and groom their psychological problems to improve the quality of life in elder people.
Aged ; China ; epidemiology ; Humans ; Polysomnography ; Prevalence ; Quality of Life ; Risk Factors ; Sleep Apnea, Obstructive ; epidemiology ; Snoring ; Surveys and Questionnaires

Objective To explore the advantages of the bedside DR,taking the quality analysis of the chest image taken from the bedside digital radiography systems (DR) and computed radiography system (CR).Method All of the 900 pieces chest image taken by bedside DR,compared with the 900 pieces CR image randomly chosen.Results Bedside DR could further reduce the rate of the remake and the radiation dose,and provided more excellent image information.Conclusion The chest image taken by bedside DR has obviously advantage than CR.It can play a positive role in the diagnosis and treatment of the critical patient and surgical patient.