1.Therapeutic effects of Flupentixol and Melitracen with conventional medicine on functional gastrointestinal disease for officers and soldiers
Xiaorong REN ; Yugui CAO ; Weitao CAI ; Zhijing CUI
Clinical Medicine of China 2015;31(1):47-50
Objective To investigate the therapeutic effects of Flupentixol and Melitracen with conventional medicine on functional gastrointestinal disease of officers and soldiers.Methods Eighty-two officers and soldiers with functional gastrointestinal disease which defined by the Rome Ⅲ were randomly divided into two groups.The cases in therapy group were treated with Flupentixol and Melitracen combined with conventional medicine,and the cases in control group were simply treated with conventional medicine.The scales changes of clinical eddicacy,sympotoms,depression,anxiety amd the quality of life at the beginning and 8 weeks 'treatment were recorded.Results All offers and soldiers completed the therapy,and the overall response rate was 92.68% in the therapy group and 70.13% in the control group(x2 =6.61,P <0.05).The general severity score of symptoms,the score of depression and the score of anxiety in the therapy group after treatment were significantly lower than that of before treatment (t =27.76,16.24,16.28 ; P < 0.05),while there were no significant difference in the control group(P > 0.05).The score of the quality of life in the therapy group (SF-36) after treatment was improved significantly than that of before treatment (P < 0.05),and the difference of two group was significant (P > 0.05).Conclusion The therapy scheme of Flupentixol and Melitracen with conventional medicine on offiers and soldiers with functional gastrointestinal disease can improve the total effective rate,clinical symptoms,depression,anxiety and the quality of life.
2.Investigation of nutritional risk, malnutrition and nutrition support in patients with gynecologic malignant tumors
Jianghong LI ; Aiming LYU ; Qiubo LYU ; Fang ZHAI ; Zhijing LIU ; Hongyuan CUI ; Mingwei ZHU
Chinese Journal of Clinical Nutrition 2014;22(5):273-276
Objective To investigate the prevalence of nutritional risk and malnutrition,and the application of nutrition support in hospitalized patients with surgically treated gynecologic malignant tumors.Methods 237 hospitalized patients with malignant tumors receiving surgery in Department of Gynecology of Beijing Hospital from January 1 to December 31,2013 were continuously sampled.Nutritional Risk Screening 2002 (NRS 2002) was performed in the morning the day after admission.NRS 2002 score ≥ 3 was considered indicating nutritional risk.Malnutrition was judged in accordance with NRS 2002.The application of postoperative nutrition support was recorded.Results The nutritional risk screening was applicable in all the patients (100%).The prevalence of malnutrition was 5.1% (12/237) in the whole study population,9.2% in the elderly (≥65 years),significantly higher than that in the patients < 65 years (2.7%) (P =0.034).The nutritional risk rate was 21.1% (50/237),which was 29.9% in the patients ≥ 65 years and significantly lower in the patients < 65 years (16.0%) (P =0.014).The nutritional risk rate in the patients with ovarian and endometrial cancers was higher the rate in those patients with vaginal and vulvar cancer was lower.47 patients (19.8%)received postoperative nutrition support,all being parenteral nutrition,including total parenteral nutrition in 13 patients (5.5%) and single transfusion (providing two or more than two amongs glucose,fat emulsion,andi amino acids) in 34 (14.3%).Tube feeding was not applied in all the patients.33 cases (66%) in the 50 patients with nutritional risk were supported by parenteral nutrition,while 14 cases (7.5%) in the 187 patients without nutritional risk were supported by parenteral nutrition.Conclusions There is nutritional risk in the patients with gynecology malignant tumors,the rate of which is higher in elderly patents (≥ 65 years) than in the patients of other age groups.Therefore,attention must be paid to ensure adequate postoperative nutrition support in the elderly patients.