1.Mitomycin C as an adjuvant in glaucoma surgery
Ophthalmology in China 1993;0(03):-
The most common cause of glaucoma filtration surgery failure is cicatrization secondary to fibroblast proliferation and of collagen. The high-risk factors for filtration failure include young age, aphakia, inflammation, neovascularization, and previous failure of filtration operation. Studies have shown beneficial effects of a single dose intraoperative mitomycin C,an antimetabolite, in inhibiting fibroblast proliferation and slceral wound cicatrization, thereby promoting success in eyes of poor surgical prognosis. Corneal complications have been minor.
2.Development on real-time bi-directional synchronous transmission system for medical demonstration and teaching
Chinese Medical Equipment Journal 2004;0(09):-
In order to supply a gap of PACS which is unidirectional,frame transmission and lag,a demonstration and teaching system which can be used as the tech support of the academic exchanging,teaching,studying,and emulating on spot is developed.By this,the medical audio and video signals and images including the video of the operation process,the images from endoscopes,electron microscopes,and the pathological images etc.in the clinical buildings and in the terminal units including research and teaching(training and exchanging) centers,lecture theaters and the director's offices etc.can be transmitted synchronously and bi-directionally in real time.
3.Effect of Static Magnetic Field on Growth of Rat Embryonic Spinal Cord Neurons in Vitro
Lirong DUAN ; Zhijian ZHANG ; Quanyi WU
Journal of Environment and Health 1992;0(04):-
Objective To study the effects of static magnetic field (SMF) on development of rat embryonic spinal cord neurons. Methods Primary cultured embryonic spinal cord neurons of Wistar rat were exposed to 1.0, 10.0, 50.0, 100.0 and 200.0 mT static magnetic field. The morphological structure, cell's differentiation and proliferation of the embryonic spinal cord neurons were observed and the contents of MDA, superoxide dismutase (SOD) and protein contents in the neurons were determined. Results Static magnetic field at density of 50-200.0 mT could inhibit the differentiation and proliferation of the cells and the phenomena such as cell aggregation, detouchment of some cells, decrease of clone-formation rate and the size of the cells were observed. The contents of MDA in the cells were increased, while the activities of SOD and the level of protein were decreased. Conclusion Static magnetic field might damage the development of embryonic spinal cord neurons by enhancing the lipid peroxidation.
4.Effect of Acrylonitrile on Proliferation and Differentiation of Mouse Lung Fibroblasts in Vitro
Lirong DUAN ; Quanyi WU ; Zhijian ZHANG
Journal of Environment and Health 1989;0(06):-
Objective To approach the effect of acrylonitrile (ACN) on the proliferation and differentiation of the lung fibroblasts of mice. Methods The purification and primary culture of the lung fibroblasts(LFb)of new born mice were conducted. The cells were treated with ACN added in the medium at the varying doses of 0.01, 0.5, 1.0, 10.0, 50.0, 100.0 and 200.0 ?g/ml. The cytomorphological methods were used, the protein, malonaldehyde (MDA) and the activity of superoxide dismutase (SOD) were determined. Results No inhibitted effect on the lung fibroblasts was observed at the doses of 0.01-10.0 ?g/ml. At the doses of 50.0-200.0 ?g/ml, acrylonitrile could inhibit the differentiation and proliferation of the cells, the volume of cells became small,the rate of cell clusters decreased, at the doses of 10.0-200.0 ?g/ml, the content of protein and the activity of SOD decreased, MDA content increased. Conclusion Acrylonitrile can inhibit the proliferation and differentiation of the lung fibroblasts in mice, protein synthesis inhibition and lipid peroxidation are considered as the related factors.
5.Microsurgical treatment of the thenal wounds
Zhi CHEN ; Chunhui WU ; Zhijian YAN
Chinese Journal of Microsurgery 2000;0(04):-
Objective To explore the methods in repairing the thenar wounds by microsurgical technique Methods Since 1989, thenar wounds were restored with transfer of superficial or deep palmar arch, recombine of thenar muscle flap Patch of nerve and transplantation of flap on 21 cases Results The thumb and flap were survived The two point discrimination was 5 to 10 mm The thenar muscle streugth reached MRC 4 with satisfactory oppones fuction Conclusion The thenal wounds cna be obtained good effect being repaired by microsurgical technique
6.A feasibility analysis and research of centralized lease management mode using for medical equipment in emergency medical equipment service center of hospital
Qing WANG ; Zhijian WU ; Yinbao CHONG
China Medical Equipment 2017;14(1):98-100
Objective:To establish the emergency medical equipment rental center, not only can reduce the repeated purchase for medical equipment, but also can achieve resource sharing, reduce equipment maintenance cost, and improve utilization efficiency.Methods: To establish emergency medical equipment rental center, which adopted lease mode and centralized management mode to use equipment. Department of medical engineering managed this center and this department is responsible to ensure every clinical department can use equipment by lease method.Results: The center has optimized the resource allocation of hospital, obviously reduced equipment input cost, improved utilization rate of medical facility since it were established. This mode provided reliable service for clinical departments.Conclusion: The established rental center of emergency medical equipment has changed the traditional management mode to a new feasible mode which can improve centralized management for medical devices, reduce waste for medical resource and achieve resource sharing.
7.Study on Nosocomial Infection and Susceptibility of Related Pathogens to Antibiotics in Patients With the Systemic Lupus Erythematosus
Aiping FENG ; Yan WU ; Zhijian TAN
Chinese Journal of Dermatology 1995;0(01):-
Objective To study the percentage and the distribution of nosocomial infection, and susceptibility of related pathogens to antibiotics in patients with systemic lupus erythematosus (SLE). Methods The clinical data of in patients with SLE in our hospital from June, 1990 to June, 1998 were analyzed. The susceptibility of the pathogens to antimicrobial agents was tested by K-B paper dilution method. Results The percentage of nosocomial infection in these cases was 16.1% . The major pathogens were staphylococcas aureus, Escherichia coli and Candida. The most highly resistant microbes were E.coli, S.arueus and Pseudomonas aeruginosa. Conclusions The nosocomial infection is one of the most common complication of SLE in the in patients. It is necessary to examine the pathogens regularly and use antibacterial agents according to the susceptibility.
8.Endoscopic injection hemostasis and sequential application of sandostatin in treatment of Dieulafoy's lesion
Zhijian ZHANG ; Qiuping WU ; Xiaodong WEN
Chinese Journal of Digestion 2001;0(10):-
Objective To evaluate the efficacy of endoscopic injection hemostasis and sequential application of sandostatin in treatment of Dieulafoy's lesion. Methods After diagnosis of Dieulafoy's lesion confirmed, endoscopic injection hemostasis(EIH) together with mixture hypertonic saline and epinephrine(HSE) was performed, and then sandostatin was given consecutively for 7 days. The control group included the patients who were not given sandostatin or given just for 1 to 2 days. Results The rates of recurrent bleeding and transfer into surgery in sandostatin group were significantly lower than those in control group,(12.5% and 6.3% versus 53.8% and 46.2% respectively, P
9.Study the relationship between the monocyte chemoattractant protein-1 gene -2518G/A polymorphism and cerebral infarction of Han population in Chinese Hunan district
Shiyan CHEN ; Zhijian ZHANG ; Xiuli WU
Journal of Clinical Neurology 1993;0(03):-
Objective To investigate the relationship between monocyte chemoattractant protein-1 (MCP-1) gene -2518G/A polymorphism and cerebral infarction(CI) of Han population in Chinese Hunan district.Methods The -2518G/A polymorphism in MCP-1 gene was detected by polymerase chain reaction-restriction fragment length polymorphism analysis (PCR-RFLP) and DNA sequencing in 162 patients with CI (CI group) and 150 normal controls (NC group). The serum level of MCP-1 in the two groups was determined by enzyme-linked immunosorbent assay (ELISA).Results In CI group, genotypic frequency of GG was 39.5%, GA was 37.0%, and AA was 23.5%. The allele frequency of G was 58.0% and A was 42.0%. In NC group, genotypic frequency of GG was 27.3%, GA was 39.3%, and AA was 33.4%. The allele frequency of G was 47.0% and A was 53.0%. The frequencies of MCP-1 -2518GG genetype and G allele in CI group were significantly higher than those in CI group (all P
10.Research on higher educational personnel training of clinical Chinese pharmacy
Bing ZHANG ; Jiarui WU ; Zhijian LIN
International Journal of Traditional Chinese Medicine 2013;35(4):335-337
The personnel training is one of the core tasks of clinical Chinese pharmacy.Since the professional training of clinical Chinese pharmacy has started relatively late in China,the teaching contents and curriculum still need further improvements.This paper is aiming at analyzing the post tasks of personnel of clinical Chinese pharmacy,defining the knowledge structure of them,and learning from the characteristics of clinical Chinese pharmacy teaching systems of the foreign and domestic universities.On such basis,the paper proposes the ideas about constructing the curriculum system of clinical Chinese pharmacy,to provide a reference for the higher educational personnel training of clinical Chinese pharmacy.