1.Clinical study of cerebral arteriovenous malformation associated with hemodynamics correlative aneurysms
Yiyou LI ; Zhihui ZHU ; Zhaowei QIN ; Jianguo XIAO ; Xiaodong WANG
Chinese Journal of Postgraduates of Medicine 2013;36(32):26-28
Objective To investigate the classification of cerebral arteriovenous malformation (AVM) associated with hemodynamics correlative aneurysms and its efficiency treated by endovascular treatment.Methods The clinical data of 17 patients of AVM associated with hemodynamics correlative aneurysms undergoing endovascular treatment were analyzed retrospectively.Results Eleven cases of aneurysms with great divergence between the aneurysm and arteriovenous malformation were embolized,6 cases of aneurysms without a great divergence between the aneurysm and arteriovenous malformation,1 case of aneurysm was treated with stent,other 5 cases of aneurysms were not treated.Eleven cases of arteriovenous malformations were embolized completely,4 cases were embolized 71%-90% and 2 cases were embolized 50%-70%.Six cases with residual were given radiotherapy.Follow-up 3 months to 3 years,there were no cases of cerebral hemorrhage or death.Unhandled 5 cases of aneurysm and 1 case of stent implantation with the follow-up by using digital subtraction angiography,laneurysm with a stent was closed.Three aneurysms were disappeared and 2 aneurysms were reduced significantly among the 5 cases of aneurysms without treatment.One case of aneurysm occlusion in patients with stent implantation.Conclusions Classification based on a great divergence artery or not between the aneurysm and arteriovenous malformation is more instructive for clinical treatmen of cerebral arteriovenous malformation associated with hemodynamics correlative aneurysm.If it has not a great divergence artery between aneurysm and arteriovenous malformation,arteriovenous malformation after a thorough treatment,aneurysms need not be treated.The endovascular treatment for cerebral arteriovenous malformation associated with hemodynamics correlative aneurysms has a good efficiency and can be treated as a priority.
2.Study on the construction of standards of review for oncology nursing professional training base with Delphi method
Lili ZHANG ; Zhihui YANG ; Huiying QIN ; Yang ZHAO
Chinese Journal of Practical Nursing 2014;30(15):59-62
Objective In order to construct the standards of review for oncology nursing professional training base by aggregating the requirement of the professional training base in multiple regions in China.Methods Delphi expert consultation method by self-designed questionnaire were conducted among 21 nursing educators in medical university,nursing administrators,oncology clinicians,oncology clinical nurse specialists in hospitals.Results The Cr,Cronbach's α was 0.825,0.980.A standards of review for oncology nursing professional training base included 5 first-level indicators,19 second-level indicators and 76 third-level indicators after three rounds of consultation.Conclusions The 100-item for standards of the review is reliable and valid,which can provide objective and quantitative standards for evaluation,assessment and access of oncology nursing professional training base.
3.Chromosome translocation t (11;18) and expression of BCL10 protein in gastric mucosa-associated lymphoid tissue lymphoma
Zhihui YI ; Qin OUYANG ; Gandi LI ; Al ET ;
Chinese Journal of Digestion 2001;0(09):-
Objective To detect chromosome translocation t (11;18)(q21;q21) and expression of BCL10 protein in gastric mucosa associated lymphoid tissue (MALT) lymphoma. Methods We, combining clinical and pathological data, detected API2 MLT fusion by reverse transcriptase polymerase chain reaction (RT PCR)as well as the expressions of BCL10 protein and Ki 67 by immunohistochemistry in cases of gastric MALT lymphoma and follicular gastritis (FG) and analyzed the relationships among them. Results API2 MLT fusion was detected in three cases (2 low grade and 1 low to high grade) out of 14 cases of gastric MALT lymphoma, and no in 8 cases of FG. BCL10 protein was weakly expressed in cytoplasm of B cells of germinal center in lymph follicles of FG; but abundantly in cytoplasm of tumor cells in gastric MALT lymphoma; 42.5% of the latter showed weak expression in nucleus. The expression of Ki 67 was significantly higher in low to high and diffuse large B cell lymphoma cases than in low grade cases( P 0.05), the frequency of nuclear expression of BCL10 increased with the increased expression of Ki 67. Conclusions Both API2 MLT fusion and BCL10 nuclear expression are associated with transformation of gastric MALT lymphoma from LG to HG. RT PCR technique used to detect API2 MLT fusion may be an important tool in identification of t(11;18)(q21;q21).
4.Survey on Natural Nidus of Metorchis orientalis in Huaihe River Basin
Yuxia ZHU ; Entao SUN ; Chaopin LI ; Zhihui QIN
Chinese Journal of Parasitology and Parasitic Diseases 1987;0(01):-
Parafossarulus striatulus, Pseudorasbora parva and brood ducks are involved in the lifecycle of Metorchis orientalis. Natural nidi of M.orientalis are confirmed in Huaihe River Basin.
5.Setting the weight of the accreditation standards for oncologic nursing professional training base
Lili ZHANG ; Zhihui YANG ; Yang ZHAO ; Huiying QIN
Chinese Journal of Practical Nursing 2015;31(10):726-729
Objective To promote the development of oncologic nursing by establishing the accreditation standards for oncologic nursing professional training base.Methods In the early stage Delphi method was used to make a consultation with 21 experts for the construction of accreditation standards for oncologic nursing professional training base.Then the weights of each level was determined by using Analytic Hierarchy Process (AHP).Results Five first-level indicators were established,including oncologic nursing,clinical practice teaching staff,training management,the basic conditions of the department and the basic conditions of the hospital,their weights were 0.385 5,0.248 4,0.160 0,0.121 3 and 0.084 9.Conclusions The accreditation standards for oncologic nursing professional training base is constructed by AHP.It can make the accreditation standards more scientific and reliable to provide a quantitative basis for the review.
6.Differences of Ventilation Function in Patients Between Chronic Right Heart Failure Secondary to Pulmonary Arterial Hypertension and Chronic Whole Heart Failure Secondary to Left Heart Diseases
Weihua LIU ; Zhihong LIU ; Qin LUO ; Qing ZHAO ; Qunying XI ; Xiuping MA ; Zhihui ZHAO
Chinese Circulation Journal 2014;(12):996-999
Objective:To study the differences of ventilation function in patients between chronic right heart failure secondary to pulmonary arterial hypertension and chronic whole heart failure secondary to left heart diseases.
Methods:A total of 102 patients with clinical stable chronic heart failure (CHF) were studied. The patients were divided into 2 groups:Whole heart failure (WHF) group, n=41 and Right heart failure (RHF) group, n=61. The ventilation function test at rest and cardiopulmonary exercise test (CPX) were conducted and compared between 2 groups.
Results: The rest ventilation function was similar between 2 groups. For CPX examination, compared with WHF group, RHF group had the lower peak minute ventilation (VE), higher anaerobic threshold and peak minute ventilation/CO2 production (VE/VCO2), higher peak dead space volume/tidal volume (VD/VT), all P<0.05.
Conclusion:At exercise condition, RHF patients had decreased ventilation function and ventilation index due to severe abnormality of ventilation/perfusion (V/Q).
7.Study on effects of Lymnaeidae size on infection of Trichobil-harzia living in Huaihe River system
Sichun SHENG ; Mingqun ZHANG ; Yan TAI ; Shigang NI ; Haifeng TANG ; Zhihui QIN
Chinese Journal of Schistosomiasis Control 1989;0(03):-
F0.01(1,5)=16. 30,P0. 05). Conclusion Laboratory results thus suggest that infection intensity is related to snail size per se, whereas prevalence in the field is related to snail size only through the correlation between size and age. In addition, under these experimental conditions, infected snails were no larger than uninfected snails, so the gigantism snails observed in the field might not be attributable to Trichobilharzia-induced effect.
8.Drug Resistance Supervision to Pathogens from Urinary Tract in Mountain Area of Western Hubei Province
Jun WANG ; Hua LIU ; Xuefeng ZHANG ; Shusheng QIU ; Bin PENG ; Jimao QIN ; Quan TANG ; Zhihui YE
Chinese Journal of Nosocomiology 2006;0(06):-
OBJECTIVE To investigate the distribution and drug resistance status to pathogens from urinary tract and offer scientific evidence for reasonable usage of antibiotics.METHODS Totally 389 isolates derived from infected urinary tract in mountain area of western Hubei Province from 2002 to 2005 were identified and antibiotic susceptibility test was performed.RESULTS Escherichia coli accounted for 66.1% ranking the first.The isolates were all susceptible to imipenem and vancomycin.The ratio of ESBLs in E.coli and Klebsiella pneumoniae was 23.7% and 25.9%,respectively.CONCLUSIONS The drug resistance rate in isolates derived from infected urinary tract of patients in mountain area was lower than in plain region of Hubei Province.
9.Preliminary Study on the Ecology of Trichobilharzia Cercariae in the Huaihe River System
Sichun SHENG ; Zhihui QIN ; Minqun ZHANG ; Yan TAI ; Shigang NI ; Jiyue WEN
Chinese Journal of Parasitology and Parasitic Diseases 1997;0(06):-
Objective To investigate the ecological habit and characteristics of Trichobilharzia cercariae in the Huaihe river system. Methods During June of 2002-May of 2003, Radix auricularia snails were collected monthly in Yaohe Fishery of the branch of the Huaihe River. The cercariae, released from the positive snails and collected by Shade Drop Bottle, were examined by direct press. Ducklings were infected by cercariae with different ages and examined for the infection by miracidia hatching method.Results The results showed a typical seasonal fluctuation in infection rate of the snails, i.e. the cercariae detection rate was 0.81% in July, 0.65% in June, 0.07%-0.26% in April, May, August, September and October respectively, with a significant difference (? 2=26.73, P
10.Raman spectroscopy of bone marrow mesenchymal stem cells in medium-frequency pulsed electromagnetic fields
Xiangrong CUI ; Wei SU ; Zhihui WU ; Lingjing MENG ; Zhao HUANG ; Wanan QIN
Chinese Journal of Tissue Engineering Research 2014;(37):5929-5934
BACKGROUND:Studies about low-frequency pulsed electromagnetic fields interfering with bone marrow mesenchymal stem cells proliferation and differentiation are many, but the Raman spectra of single stem cells irradiated in electromagnetic fields analyzed by surface Raman spectroscopy analysis are rarely reported. OBJECTIVE:To compare the difference in Raman spectra of bone marrow mesenchymal stem cells with or with no irradiation of 3 000 Hz pulsed electromagnetic fields. METHODS:Bone marrow mesenchymal stem cells isolated from Sprague-Dawley rats were cultured and identified. Passage 3 cells were inoculated into 6-wel plates and divided into two groups:pulsed electromagnetic field irradiation group and blank control group. After cultured for 7 days, cells in the two groups were transferred to physiological saline, and 30 cells were randomly col ected from each group. Four Raman spectra were harvested from each celland the average relative intensity of Raman spectra was calculated and compared between two groups. RESULTS AND CONCLUSION:There were the same Raman peaks in the two groups, and the waveforms were basical y same in the two group based on the curve mapping by origin 7.0 software. The peak value in the irradiation group was decreased compared with the blank control group. Laser optical tweezers Raman spectroscopy can be applied to study the biochemical changes of a single stem cellat the molecular level. The Raman spectra of bone marrow mesenchymal stem cells irradiated by 3 000 Hz pulsed electromagnetic fields differ from those without irradiation, and the peak also lowered after irradiation.