1.Therapeutic efficiency of seretide plus montelukast on patients with asthma and effect on the serum IL-6 and TNF-α
Liming LUO ; Wenqing CHEN ; Biao HUANG ; Zhihe CHEN ; Guochun HUANG
Chinese Journal of Primary Medicine and Pharmacy 2009;16(z1):4-5
Objective To investigate the effect of seretide plus montelukast on clinical symptoms、pulmonary functions and the serum IL-6 and TNF-α of patients with asthma.Methods 73 cases patients with asthma were randomly divided into seretide group and seretide plus montelukast group and were treated respectively for two weeks.The clinical symptoms,lung functions and serum IL-6,TNF-α contents of patients were measured respectively before treatment and after two weeks treatment.Results After two weeks treatment,the clinical symptom scores、FEV1.0、FVC and PEFR of two groups had significantly changed than that before treatment(P<0.05);Each index was further compared after treatment,and it was found that two groups had significant differernces statistically (P<0.05),these showed that combination of seretide and montelukast could significantly enhance the therapeutic effect.After treatment,the TNF-α and IL-6 contents in the peripheral blood of seretide group and seretide plus montelukast group had both significantly reducted (P<0.05 or P<0.01);The TNF-α and IL-6 contents of seretide plus montelukast group had reduced more significantly than that of the seretide group(P<0.05).Conclusion The seretide plus montelukast group could improve the clinical symptoms and pulmonary function of patients with asthma,and the action mechanism might be related to lower the serum IL-6 and TNF-α contents.
2.Investigation of magnetic motor evoked potentials in patients with Graves′ disease
Shaoda LIN ; Meiyun GUO ; Xiaohua CHEN ; Zhihe HUANG
Chinese Journal of Endocrinology and Metabolism 1986;0(04):-
Magnetic motor evoked potentials (MEP) were measured in 46 patients with Graves′ disease (GD) and 50 normal controls, and its latency、amplitude and central motor conduction time (CMCT) were recorded. Prolonged latency, lowed amplitude and shortened CMCT in MEP suggest the damage of the neurons.
3.Analysis in treatment of femoral peritrochanteric fracture by internal fixation
Guoqiang LU ; Xinzhi LI ; Zhihe ZHENG ; Jing HUANG
Chinese Journal of Postgraduates of Medicine 2006;0(05):-
Objective To explore the surgical types in fractures of the proximal femur by internal fixation. Methods One hundred and three cases of femoral peritrochanteric fracture underwent operation were studied retrospectively. According to AO classification, the cases of each type were treated by four methods of internal fixation: the cannulated compression screw, dynamic hip screw (DHS), anatomical plate and proximal femoral nail (PFN). Results All patients were followed up from 6 to 40 months. All fractures were healed. Complications occurred in 9 patients, including aseptic necrosis of the femoral head in 2, coax magna in 7. According to Sanders standard of function of joint, the final effect was satisfactory. Conclusion It is important to select different surgical types according the different peritrochanteric fracture separately.
4.Modified Latarjet splitting subscapularis muscle under arthroscopy: an anatomical study based on axillary nerve, glenoid, and subscapularis muscle.
Xinzhi LIANG ; Daqiang LIANG ; Zhihe QIU ; Sheng LI ; Bing WU ; Hao LI ; Gang HUANG ; Wei LU ; Denghui XIE ; Haifeng LIU
Chinese Journal of Reparative and Reconstructive Surgery 2023;37(5):556-560
OBJECTIVE:
To testify the spatial relationship between the subscapularis muscle splitting window and the axillary nerve in modified arthroscopic Latarjet procedure, which could provide anatomical basis for the modification of the subscapularis muscle splitting.
METHODS:
A total of 29 adult cadaveric shoulder specimens were dissected layer by layer, and the axillary nerve was finally confirmed to walk on the front surface of the subscapularis muscle. Keeping the shoulder joint in a neutral position, the Kirschner wire was passed through the subscapularis muscle from back to front at the 4 : 00 position of the right glenoid circle (7 : 00 position of the left glenoid circle), and the anterior exit point (point A, the point of splitting subscapularis muscle during Latarjet procedure) was recorded. The vertical and horizontal distances between point A and the axillary nerve were measured respectively.
RESULTS:
In the neutral position of the shoulder joint, the distance between the point A and the axillary nerve was 27.37 (19.80, 34.55) mm in the horizontal plane and 16.67 (12.85, 20.35) mm in the vertical plane.
CONCLUSION
In the neutral position of the shoulder joint, the possibility of axillary nerve injury will be relatively reduced when radiofrequency is taken from the 4 : 00 position of the right glenoid (7 : 00 position of the left glenoid circle), passing through the subscapularis muscle posteriorly and anteriorly and splitting outward.
Adult
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Humans
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Shoulder
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Rotator Cuff/surgery*
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Arthroscopy/methods*
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Scapula/surgery*
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Shoulder Joint/surgery*
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Cadaver
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Joint Instability/surgery*