Objective To evaluated the efficacy of lentinan injection and carboplatin for malignant pleural effusions.Methods 63 patients were divided into the experimental group and control group.The experimental group were adminstered lentinan injection and carboplatin.Results The response rate of the experimental group was 81.2%,the control group was 61.3%.The better quality of life appeared in the experimental group.Conclusion Postoperative lentinan injection and carboplatin in formalignant pleural effusions is a beneficial therapeusis that helps to improve survival rates and qulity of life.

Objective To study transthoracic photograph for shoulder joint with DR. Methods The advantages and disadvantages of three photography methods were discussed and analyzed. Results DR dual-detector and post-processing did good to transthoracic photograph. Conclusion Transthoracic photograph for shoulder joint at non-conventional positions is very significant.

The angle of tibial torsion is an inherent angle in human bodies.The angle has been to knew of clinical workers.But the research of mechanism for angle of tibial torsion and relationship with some disease still in initial stage.Recent years,the angle of tibial torsion has been noticed with the concept of torsionaldeform appearance.This paper summarizes measurement of the angle of tibial torsion andits advancement of correlated research.

Objective To investigate the influence of lumbar epidural anesthesia on cell apoptosis in rat kidneys with ischemia-reperfusion injury.Methods Thirty male Wistar rats were divided into three groups at random,including a sham-operated group,a model group,and an anesthesia group.Then the local norepinephrine,local angiotensin Ⅱ,plasma superoxide dismutase,plasma malondialdehyde and cell apoptosis index were observed at the 24 h after the reperfusion in rat kidneys of ischemia 60 min.Results Compared to the sham-operated group,ischemia-reperfusion of kidney caused a significant increase in contents of local norepinephrine,local angiotensin Ⅱ],and malondialdehyde in the model group and anesthesia group as well as increasing in the cell apoptosis index (P ＜ 0.05),and those parameters above were lower in the anesthesia group than those in the model group (P ＜0.05).Meanwhile,the activities of plasma superoxide were higher than those in model group (P ＜ 0.05).Conclusions The lumbar epidural anesthesia can reduce the excessive accumulation of neuroendocrine hormone in kidney,alleviate oxidative stress,which plays an important role in restraining the ischemia-reperfusion injury and cell apoptosis.

Objective To compare the effect of Zhigancao Decoction and Zhenwu Decoction on hemodynamics, matrix metalloproteinase-9 (MMP-9), tissue inhibitor of metalloproteinase-1 (TIMP-1) and myocardial enzyme of elderly patients with chronic heart failure.Methods 40 elderly patients with chronic heart failure in the first affiliated hospital of the medical college, Shihezi university were selected and randomly divided into Zhigancao Decoction group (n=20) and Zhenwu Decoction group (n =20) .The both of two groups were given conventional treatment, then were treated with respective drug according to different groups with two courses, one course of two weeks.The hemodynamic, MMP-9, TIMP-1 and myocardial enzyme spectrum indexes of two groups were compared post-treatment.Results After treatment, the indexes of hemodynamics in two groups were improved, hemodynamic indexes of Zhigancao Decoction recovered better than those of Zhenwu Decoction (P<0.05) .The serum MMP-9, MMP-9/TIMP-1 of Zhigancao Decoction group were lower and TIMP-1 was higher than those of Zhenwu Decoction group (P<0.05).The myocardial enzyme indexes in both groups were lower post-treatment, and the above indexes in Zhigancao Decoction were lower than those in Zhenwu Decoction group (P<0.05) . Conclusion Zhigancao Decoction could obviously improve the symptoms of chronic heart failure in elderly patients, which has the guiding significant in the clinical treatment.

Objective To provide anatomical basis for reconstruction thumb of free bifoltaed bone flap pedicled with the dorsal carpal branch of ulnar artery. Methods After red latex was infused into the arteries of 35 sides of adult cadaveric upper limbs, the origin, course, branches, diameters, skin branches and periosteal branches of dorsal carpal branch of ulnar artery were observed, to initate operation experiment of reconstruction thumb on 1 sides. Results The dorsal carpal branch begins with ulnar artery (4.0?1.0)cm above the pisiform with diameter of (1.3?0.5)mm, its pedicle ranges(1.2?0.5)cm and branches off into ascending and descending branches. There were outer diameter range(0.8?0.3)mm and (1.1?0.2)mm. Skin branches of dorsal carpal branch of ulnar artery nourinshed the forearm ulnar side, carpal and dorso-ulnar aspect of mid-hand, periosteal branches of dorsal carpal branch of ulnar artery nourished the anterior internus side of the ulnar and the fifth metacarpal bone. Conclusion The free bifoltaed bone flap pedicled with the dorsal carpal branch of ulnar artery is available to reconstruction the thumb.

OBJECTIVE:To promote rational drug use in the clinic. METHODS: By reviewing the pertinent literature both at home and abroad, the causes of ADRs induced by Chinese medicine injections were analyzed. RESULTS: the reasons accountable for ADRs induced by Chinese medicine injections were as follows: the active ingredients in the Chinese herbal medicine; poor stability of preparation and the unreasonable preparation process; failing to follow indications in the treatment, drug incompatibility, improper dosage, improper administration and individual differences. CONCLUSION: It is necessary to strengthen monitoring in clinical application of Chinese medicine injections. Only through strictly following indications, probing into allergy history before drug use, making sure the quality of the injection is qualified, paying special attention to drug compatibility can the ADRs be greatly reduced or avoided.

Objective To analyze the clinical,radiologic and pathological features of endobronchial metastasis from prostate cancer, and its diagnosis and treatment. Methods Ten cases of endobronchial metastasis from prostate cancer with pathological evidence in our hospital were retrospectively analyzed.The clinical, radiologie andpathological features and the diagnostic procedures and treatment of the cases were reported and analyzed while combined with literature. ResultsAn average age at diagnosis of advanced prostate cancer was 65.5 years. Emoptysis(5/10), cough (4/10), dyspnea (4/10) and weight loss (5/10) were the common symptoms.Chest X-ray disclosed hilar and mediastinal lymphadenopathy (4/10), hilar mass (3/10) or atelectasis (2/10) . Bronchoscopic examination revealed that most of lesion located in single lobar or segmental bronchus (6/10). Bilateral upper lobe were most susceptibly involved(7/10). Polypoid lesions or mass in lumen of bronchi(8/10)were more frequent than infiltrative lesion(2/10), which could obstruct the orifice of the bronchi in different extent. Immunohistochemical staining for prostate specific antigen or prostatic acid phosphatase was positive, and most patients responded well to endocrine therapy. Conclusions Clin.ical and radiologic features of endobronchial metastasis from prostate cancer are similar to those of primary bronchogenic carcinoma. Immunohistoehemical study is helpful for differential diagnosis and the short-term efficacy of endocrine therapy is significant.

Objective To analyze and compare the clinical features of community-acquired pneumonia caused by Legionella in elderly (age≥60 years) and younger patients. Methods The epidemiological, clinical, laboratory data and the outcomes of 80 cases with community-acquired Legionella pneumonia (CALP) from January 2001 to October 2009 were studied retrospectively, and the differences between elderly and younger group were compared using univariate and multivariate analysis. Results (1) Underlying diseases, such as cerebrovascular diseases, chronic obstructive pulmonary diseases, diabetes mellitus and immunosuppressive therapy were significantly more frequent in elderly group than in younger group (all P＜0. 05). (2) No significant differences were observed between the two groups in legionella serotype. (3) Malaise, hyponatremia and hypophosphatemia were all more frequent in elderly group than in younger group (x2=5. 300, 5. 520, 4. 470; P=0. 021,0. 019, 0. 034, respectively). And elderly versus younger group had higher creatinine levels [(108.55±56.57) μmmol/L vs. (75.42±17.62) μmmol/L, t= -3. 062, P=0. 002], lower PaO2/FiO2 (＜300) (57.7% vs. 29.2%, x2=4. 120, P=0.042), less leucocyte counts [(8.34±3.65)×109/Lvs. (10.63±5.02)×109/L, t=-2.287, P=0.022]. (4) Elderly patients more likely complicated with congestive heart failure (P=0.037) and their length of staying in hospital was also longer (Z=-2.194, P=0.028). No significant differences were observed between the two groups in mortality, intensive care unit admission, and the need for corticosteroids or mechanical ventilation.Conclusions Elderly patients with CALP have a higher frequency of underlying comorbidities and more organs involvement than younger patients, although greater severity of illness at onset and outcome are not significantly different between the two groups.

NKR and TLR are most important receptor superfamilies in innate immunity and act as first line of host defense against infection. Those receptors exert peculiar recognition mechanisms to sense danger signals and distinguish infectious nonself from noninfectious self. More importantly, they coordinate and regulate each other and therefore play major roles in initiation of innate immunity and also help to direct adaptive immune responses. The importance of recognition and interaction of those receptors are highlighted. The precise mechanisms can be harnessed to aid the rational design of therapy against infection, inflammation, cancer or autoimmune diseases.