Objective To investigate the feasibility and safety of periareolar incision in treating gynecomastia, and whether it produces good cosmetic effects. Methods A total of 42 patients with gynecomastia treated by micro-incision of areola were retrospectnely anslyzed. Results The operation was successfully performed in all the 42 patients. Follow-up was done for 3 to 24 months, the surgical scars were obscure, and the sensation of nipple or areola were good. No operation-related complications were observed. Conclusion The periareolar incision in the treatment of gynecomastia was feasible and recommendable in terms of cosmetic maintenance and safety.

Statistical analysis of TCM syndrome differentiation and clinical symptoms were made in 163 cases of diseases of digestive tract. It was found that the patients of abnormal defection or tendecy of abnormal defecation with the hyperactive liver - Qi attacking the spleen, stagnation of liver-Qi due to hypofunction of the spleen, loose stool due to deficiency of the spleen, constipation due to Qi-deficiency, constipation due to Qi - staganation syndromes accounted for 60%- 100%. Elecrtic examination of colon on the body surface and analysis of frequancy spectrum found that hyperelectroactivity of low - frequency and high - frequency segment of colon and contractive complex myoelectric hyperactivity in the patients of the hyperactive liver - Qi attacking the spleen; hyperelectroactivity of high - frequency segment of the ascending and descending colon and contractive complex myoelectric hyperactivity and decrease of electric activity of high - frequency segment of the sigmoid colon in the patients of loose stool due to hypofunction of the spleen: obvious decrease of electric activiy of low - frequency and high-frequency of the colon and contractive complex myoelectric hyperactivity in the patients of constipation due to deficiency of Qi or Qi - stagnation, but electric activity of the high -frequency segment of the colon and contractive complex myoelectric activity after meal in the patients of constipation due to Qi -stagnation was stronger than that in the patients of constipation due to Qi - deficiency. Electric frequency spectrum of colon can indirectly reflect changes of colon dynamics of different syndromes, and it can partially expain the changes of stool and the mechanism of relative symptoms.

Objective To evaluate the diagostic value of hypersensitive C-reactive protein(hs-CRP),β2-microglobulin(β2-MG) and cystatin C(Cys-C)tests in diabetic nephropathy(DN)of early stage.Methods The turbidimetric immunoassay was adopted to determine serum hs-CRP,β2-MG and Cys-C concentrations in type 2 diabetic patients,including 100 cases with DN of early stage (DN group),50 cases without DN(NDN group)and 100 cases healthy controls(control group).Results Serum hs-CRP,β2-MG and Cys-C concentrations in DN group were significantly higher than that in control group and NDN group(P <0.05).Conclusion Hs-CRP,β2-MG and Cys C are sensitive indicators in the diagosis of DN.The combined determination of the three indicators im-proves the sensitivity of early DN diagnosis and is useful for monitoring the development of DN in early stage.

In 51 patients with gastrointestinal diseases,diseases,abdondnal X-lay Photos at lying POSition weretaken 6.5 hours after barium ined and 12 healthy volunteers served as coneal. The longitudinal axis,the transverse diameter,the number and the height of colonic bags in the colonic X-ray photes at fillingand evacuating Phases were counted.Chronic colitis was mainly manifested as loose stool, alternation ofconstipation and diarrhea,dyschesia or abdominal pain whenever desire to defecate. The colonic X-rayphotos showed that the diameter and the number of colonic bag in chronic colitis were reduced and the evacuation of barium became accelerated.These colonic X-ray images can explain the pathophysiologicmechasm of the above manifestations and may serve as a kinetic index providing evidence for the clinicaldiagnosis and treatment of the disease.

0.05 ),and the gastric evacuation rate in SDS group was lower than Group C(P

Objective To analyze the merger candida albicans pulmonary tuberculosis irfection risk factors, clinical characteristics,treatment and prognosis,ways of improving the coexistence of the two diseases in the early di-agnosis and treatment methods. Methods 86 cases with pulmonary tuberculosis combined candida albicans infection were analyzed. Results Pulmonary lung infection candida albicans no specific clinical manifestations, in addition to X-ray signs of tuberculosis,mainly for the merger under the shadow of lung flake fuzzy; prediction for risk factors: long-term use of broad-spectrum antibiotics, the multi-antibiotics, glucocorticoid or immunosuppreasanta, long-term bed rest, physical weakness, the length of hospitalization, chronic bronchitis and obstructive pulmonary disease (COPD), respiratory failure, mechanical ventilation, diabetes, hypoproteinemia, blood diseases, multiple organ failure,mechanical ventilation,and other invasive operation is closely related to a higher mortality rate of pulmonary fungal infections. Conclusion Active tuberculosis disease and therapy to reduce risk factors, prevention and early diagnosis of good,reasonable use of antibiotics,hormones,and so un,the key is to improve the cure rate.

Objective To evaluate the value of multi-slice spiral CT Low-dose scanning technology in thyroid enhanced scan. Methods Eighty patients were randomly divided into four groups including Group A:120 kV,180 mA;Group B:120 kV,100 mA;Group C:100 kV,180 mA and Group D:100 kV,100 mA.The subjective image quality was evaluated and scored.Thyroid CT val-ue,image background noise (N),image signal to noise ratio (SNR),CT dose index (CTDIvol),dose length product (DLP),and the effective radiation dose (ED)were measured and compared.Results The subjective image scores and SNR of these four groups were 3.90±0.31 and 26.34±3.13,3.75±0.44 and 25.08 ±1.87,3.70 ±0.47 and 25.86 ±2.38,3.60 ±0.60 and 24.87 ±2.20 respectively.There were no significantly statistical differences among the subjective image scores and SNR (P > 0.05 )of the 4 Groups.Thyroid CT values,N,CTDIvol,DLP and ED were (1 68.55 ± 13.39)HU,(6.48 ±0.84)HU,(10.95 ±0.00)mGy, (145.67±8.79)mGy·cm,(0.73±0.04)mSv in Group A,(170.70±11.34)HU,(6.83±0.45)HU,(6.08±0.00)mGy,(84.58± 4 .9 4)mGy· cm,(0 .4 2 ±0 .0 3 )mSv in Group B,(1 8 5 .2 0 ±2 2 .3 5 )HU,(7 .1 9 ±0 .8 6 )HU,(6 .5 9 ±0 .0 0 )mGy,(8 9 .8 6 ± 3 .2 6 )mGy· cm,(0 .4 5 ±0 .0 3 )mSv in Group C,(1 9 0 .5 5 ±2 1 .3 8 )HU,(7 .6 6 ± 1 .0 1 )HU,(3 .6 6 ±0 .0 0 )mGy,(5 0 .2 0 ± 1 .8 9 )mGy·cm,(0.25±0.01)mSv in Group D respectively.There were significantly statistical differences among different thyroid CT values,N,CTDIvol,DLP and ED (P <0.05).Conclusion Multi-slice spiral CT low-dose scanning technology in thyroid en-hanced scan can guarantee the image quality and effectively reduce thyroid radiation dose.

Objective To investigate the molecular mechanism of the glucocorticoid?induced osteoblasts apoptosis,and to develop the effective intervention measures. Methods The MC3T3?E1 cells were treated with different concentrations of dexamethasone for 24 hours,then the apoptosis rate was detected with TUNEL analysis,the intracellular expression of Bim and Bax were determined by Westen blot. In addition,MC3T3?E1 cells were randomly divided into Bim?siRNA group,negative control siRNA group and control group. Twenty?four hours after transfection,10-4mmol/L dexamethasone was added to each group of cells for another 24 hours administration. The apoptosis rate was analyzed using the TUNEL,the mito?chondrial transmembrane electric potential was detected by flow cytometry after JC?1 staining,the expression of Bax,Bcl?2 in mitochondrial and Cyt?C,AIF in cytosolic were determined by Western blot. Results The rate of osteoblast apoptosis and Bim expression in cells were both significantly in?creased with the dosage of dexamethasone,there was no significant difference between the groups in the expression of Bax;the rate of osteoblast apop?tosis after the expression of silence Bim was significantly lower than the negative control siRNA group and control group,the expression of Bax and Cyt?C,AIF in cytosolic were significantly reduced,and the mitochondrial transmembrane electric potential was increased. Conclusion Bim is the key molecules in hormone?induced apoptosis of osteoblasts ,the expression of silence Bim can inhibit dexamethasone induced osteoblasts apoptosis through the mitochondrial pathway.

Endoscopy ; Gelatin ; Gentamicins ; administration & dosage ; Humans ; Paranasal Sinuses ; surgery ; Triamcinolone Acetonide ; administration & dosage ; Wound Healing ; drug effects

OBJECTIVE: To evaluate the efficacy of chinese traditional treatment after functional endoscopic sinus surgery (FESS) for patients with chronic sinusitis. METHOD: Eighty-eight cases of patients with chronic sinusitis were randomly divided into control group and treatment group after FESS and followed for 3 months. The control group received routine treatment. The treatment group received Chinese traditional treatment on the basis of routine treatment. VAS scores, Lund-Kennedy scores and Lund-Mackay scores were employed to conduct the subjective and objective assessment, comprehensively evaluate the clinical efficacy before and after treatment. RESULT: (1) After 3 months of treatment, the two groups of VAS scores and Lund-Mackay scores were significantly improved before treatment (P<0. 05). (2)After 3 months of treatment, the effectiveness of the control group was 81. 8%, treatment group was 97. 7%, the difference was statistically significant(P<0. 05). CONCLUSION Chinese traditional treatment after FESS can reduce postoperative mucosal edema and promote the postoperative recovery of sinus mucosal inflammation, is effective in preventing the recurrence of postoperative.
Chronic Disease ; Endoscopy ; Humans ; Medicine, Chinese Traditional ; Paranasal Sinuses ; surgery ; Postoperative Period ; Sinusitis ; drug therapy ; surgery ; Treatment Outcome