1.Periareolar incision in treatment of gynecomastia
Xiaohua WANG ; Jianan CHEN ; Zhicheng LIANG
Chinese Journal of Primary Medicine and Pharmacy 2009;16(5):838-839
Objective To investigate the feasibility and safety of periareolar incision in treating gynecomastia, and whether it produces good cosmetic effects. Methods A total of 42 patients with gynecomastia treated by micro-incision of areola were retrospectnely anslyzed. Results The operation was successfully performed in all the 42 patients. Follow-up was done for 3 to 24 months, the surgical scars were obscure, and the sensation of nipple or areola were good. No operation-related complications were observed. Conclusion The periareolar incision in the treatment of gynecomastia was feasible and recommendable in terms of cosmetic maintenance and safety.
2.Effect of Lipide on Mice Podocyte Proliferation
Hongyu CHEN ; Zhicheng QIN ; Yongjun WANG
Journal of Medical Research 2006;0(08):-
Objective To explore the effect of lipide on mice podcyte prolixferation in vitro culture.Methods MTT was used to dectect the change of the Podocyte Proliferation after the inducement of low-density-liportein(LDL)and oxide-LDL(OX-LDL).Results After 24 and 48 hours,the mice podocyte proliferation increased with the inducement of LDL,which the thickness from 6.25?g/ml to25?g/ml.And after 24 hours,the podocyte proliferation increased with the OX-LDL,which the thickness from 12.5?g/ml to 100?g/ml(compared with control,P
3.The clinical application of endoscopic thyroidectomy.
Pingkang CHEN ; Chunlei SUN ; Zhicheng XU
Chinese Journal of Minimally Invasive Surgery 2002;0(S1):-
Objective To explore the method and result of endoscopic thyroidectomy. Methods Thyroidectomy was performed endoscopically in 4 cases of thyroidoma. Results 4 patients underwent endoscopic thyroidectomy, whose operation time was 52,63,70,75 minutes respectively. An average blood loss during operation was 35ml and no complication occurred. They were discharged 4 days~5 days after operation. Conclusions The endoscopic thyroidectomy has the advantages of minimal invasion, less bleeding, less complication and quicker recovery.
4.Evaluation of ultrasonography in diagnosis of benign PH and malignant thyroid nodules by binary LogisticPHam
Zhicheng CHEN ; Yinyou FANG ; Jing SHI
Chinese Journal of Primary Medicine and Pharmacy 2017;24(16):2464-2468,后插4
Objective To evaluate the clinical value of ultrasonography in diagnosis of benignPHand malignant thyroid nodules by binary Logistic regression model.Methods A retrospective analysis of 240 cases of thyroid nodules confirmed by pathology after operation excision was conducted.173 nodules were benign as control group,67 nodules were malignant as observation group.The ultrasonic features of thyroid nodules were collected.The factor had statistics significance by x2 test between the two groups were analyzed by binary Logistic regression.A logistic regression model was created.The ROC curve was drawn and the area under the curve was calculated.Results There were statistically significant differences among boundary,aspect ratio,shape,internal echo,calcification,acoustic halo,cervical lymphadenectasis between the control group and observation group(x2=45.392,7.590,30.039,24.168,37.406,6.893,16.078,all P<0.01).And after Logistic regression analysis,six variables that entered the regression equation were boundary(P=0.000,OR=8.437),aspect ratio(P=0.000,OR=12.816),microcalcification of the nodules(P=0.000,OR=8.893),shape(P=0.000,OR=8.791),internal echoes(P=0.001,OR=8.313)and cervical lymphadenectasis(P=0.001,OR=6.891).The accuracy of the model was 90.7%(223/246)in predicting malignant nodules in thyroid.The area under the ROC curve was(0.904±0.031).Conclusion The binary Logistic regression can be used to differentiate malignant and benign thyroid nodules,and make a more accurate judgment for the nodules in thyroid.
5.Analysis on Changes of Electric Frequency Spectrum of the Colon in 163 Cases of Abnormal Defecation with Different Syndromes
Zhicheng LIAN ; Xuefen LIANG ; Weijing CHEN
Journal of Traditional Chinese Medicine 1993;0(05):-
Statistical analysis of TCM syndrome differentiation and clinical symptoms were made in 163 cases of diseases of digestive tract. It was found that the patients of abnormal defection or tendecy of abnormal defecation with the hyperactive liver - Qi attacking the spleen, stagnation of liver-Qi due to hypofunction of the spleen, loose stool due to deficiency of the spleen, constipation due to Qi-deficiency, constipation due to Qi - staganation syndromes accounted for 60%- 100%. Elecrtic examination of colon on the body surface and analysis of frequancy spectrum found that hyperelectroactivity of low - frequency and high - frequency segment of colon and contractive complex myoelectric hyperactivity in the patients of the hyperactive liver - Qi attacking the spleen; hyperelectroactivity of high - frequency segment of the ascending and descending colon and contractive complex myoelectric hyperactivity and decrease of electric activity of high - frequency segment of the sigmoid colon in the patients of loose stool due to hypofunction of the spleen: obvious decrease of electric activiy of low - frequency and high-frequency of the colon and contractive complex myoelectric hyperactivity in the patients of constipation due to deficiency of Qi or Qi - stagnation, but electric activity of the high -frequency segment of the colon and contractive complex myoelectric activity after meal in the patients of constipation due to Qi -stagnation was stronger than that in the patients of constipation due to Qi - deficiency. Electric frequency spectrum of colon can indirectly reflect changes of colon dynamics of different syndromes, and it can partially expain the changes of stool and the mechanism of relative symptoms.
6.Selection of Plants Suitable for Growing in the Arsenic Polluted Areas
Limei HUANG ; Zhicheng CHEN ; Wuli YAN
Journal of Environment and Health 1992;0(04):-
sweet potato. Conclusion The content of arsenic (Ⅲ) in the edible part of plants was one of the important factors for selecting the plants that are suitable for growing the arsenic polluted area.
7.Quality Evaluation on Methodology of Clinical Research of Yinzhihuang Injection in the Treatment of Icteric Virus Hepatitis
Huiyang CHEN ; Jun CHEN ; Zhicheng LIU ; Pingkang WEN
China Pharmacy 2005;0(13):-
OBJECTIVE:To evaluate the quality of the methodology of clinical research on Yinzhihuang injection in the treatment of icteruc virus hepatitis.METHODS:The methodology quality of77pertinent literatures was evaluated and analyzed according to the quality assessment criteria in the evaluation manual of Cochrane Reviewer's Handbook 4.2.2.RESULTS:Only 4 literatures were up to the related standards,2 of which were randomized controlled trials(RCT)and other 2 were semi-randomized controlled trials(CCT).All of the 4 studies were low quality(Grade C)researches,in which the biases on selectivity,practice,measurement and wastage were highly possible.CONCLUSION:More randomized controlled trials of high quality are needed to obtain reliable evidences on Yinzhihuang injection in the treatment of icteric virus hepatitis.
8.Central Mechanism of Acupuncture at Baihui for Memory Impairment after Stroke: A Resting- state Functional Magnetic Resonance Imaging Study
Zhicheng LIN ; Shanli YANG ; Xiehua XUE ; Jing TAO ; Lidian CHEN
Chinese Journal of Rehabilitation Theory and Practice 2015;21(2):184-188
Objective To explore the central mechanism of acupuncture at Baihui (GV20) for memory impairment after stroke. Methods 32 stroke patients were randomized to receive acupuncture at Baihui (GV20) (as observation group) and acupuncture at Yanglingquan (GB34) (as control group) for 8 weeks. At the meantime, all participants received routine treatment including physical and occupational therapies. They were scanned with resting-state functional magnetic resonance imaging (fMRI) to find functional connectivity and assessed with Wechsler Memory Scale (WMS) before and after treatment. The results of WMS and functional connectivity were analyzed with Pearson's correlation. Results The memory scores and memory quotient improved significantly after treatment in the observation group (P<0.05). The functional connectivity significantly increased occurred in the left hippocampus to right inferior frontal gyrus, right middle frontal gyrus and left inferior frontal gyrus; and right hippocampus to left middle frontal gyrus, left superior frontal gyrus and left parietal lobe. Significant correlations were found between memory quotient and functional connectivity of hippocampus to frontal lobe and left parietal lobe in the observation group. There was no statistical significance in memory scores and memory quotient in the control group. The functional connectivity significantly decreased in left hippocampus to right middle occipital gyrus, and right hippocampus to right superior temporal gyrus and right posterior lobe of cerebellum. There was no statistical correlation between functional connectivity and results of WMS. Conclusion The acupuncture at Baihui can improves memory ability of stroke patients, which may associate with the increase of functional connectivity of hippocampus with frontal lobes and parietal lobes.
9.A Preliminary Strdy colonic Motility and X-ray Images of Chronic Colitis
Haihe DENG ; Weiqing CHEN ; Xuefen LIANG ; Zhicheng LIAN
Journal of Guangzhou University of Traditional Chinese Medicine 1999;0(02):-
In 51 patients with gastrointestinal diseases,diseases,abdondnal X-lay Photos at lying POSition weretaken 6.5 hours after barium ined and 12 healthy volunteers served as coneal. The longitudinal axis,the transverse diameter,the number and the height of colonic bags in the colonic X-ray photes at fillingand evacuating Phases were counted.Chronic colitis was mainly manifested as loose stool, alternation ofconstipation and diarrhea,dyschesia or abdominal pain whenever desire to defecate. The colonic X-rayphotos showed that the diameter and the number of colonic bag in chronic colitis were reduced and the evacuation of barium became accelerated.These colonic X-ray images can explain the pathophysiologicmechasm of the above manifestations and may serve as a kinetic index providing evidence for the clinicaldiagnosis and treatment of the disease.
10.The clinical application value of serum ferritin in acute coronary syndromes
Feng PAN ; Shaoli DENG ; Zhicheng ZHANG ; Haihang MA ; Ming CHEN
Chongqing Medicine 2015;(9):1184-1185,1188
Objective To investigate the relationship of serum ferritin(SF) and acute coronary syndrome(ACS) .Methods ACS group(n= 110) was divided into unstable angina(UA) subgroup(n= 46) ,non-ST-segment elevation myocardial infarction (NSTEMI) subgroup(n=30) and ST-segment elevation myocardial infarction(STEMI) subgroup(n=34) according to clinical da-ta ,coronary angiography and electrocardiogram examination .The normal coronary patients provided as control group(n=42) .The levels of serum ferritin ,hs-CRP and serum lipids were determined and the differences of SF among the groups were analyzed .The correlation of hs-CRP ,TG ,LDL-C ,HDL-C ,TC and SF were also analyzed .Results Compared with control group ,the level of SF in UA ,NSTEMI ,STEMI were significantly increased(P<0 .05) .Comparison in the levels of SF in NSTEMI ,STEMI group and UA group had significant difference(P<0 .05) .Correlation analysis indicated that the level of SF were positively correlated with hs-CRP ,TG and negatively associated with HDL-C .Conclusion The level of SF significantly increased in patients with ACS and has a positive relationship with hs-CRP and the disorder of lipid metablism .SF helps in assessing the clinical classification and risk strati-fication in patients with ACS .