1.Application of PBL teaching mode in college English based on network teaching platform
Zhichen WANG ; Li LIU ; Ying LIU
Chinese Journal of Medical Education Research 2011;10(4):433-435
Modern information technology entered the field of education and provided basis for the shift of teaching mode.The application of PBL mode supported by Network Teaching Platform was proposed to help to develop students'capacity of autonomous learning and promote teaching quality
2."Locating Lung Block by ""Regulative Aperture Mode"" in Total Body Irradiation(TBI)"
Ping LI ; Huosheng XIA ; Zhichen LIU ; Jian ZHAO ; Kang WANG
Chinese Journal of Medical Physics 2010;27(1):1592-1593
Objective:To introduce estimate a technique ofregulative aperture methodin locating lung block in TBI.Methods:We excavated a square aperture in the foam template which is used to fasten the lung block,and the projection formed by the field light through the aperture is used as the reference for adjusting the location of the lung block.Measure the windage of lung shades and block shades by X-ray,in 8 patients.Results:windage values of head-feet and left-right orientations are smaller inregulative aperture modethan in conventional method respectively.Conclusions:Regulative aperture methodis an easy and effective technique to improve lung shielding precision in TBI.
3.Transarterial embolization of congenital pelvic arteriovenous malformation in a male(A case report and review of the literature)
Shengli CHEN ; Zhichen WANG ; Guodong CHEN ; Xi TIAN
Journal of Interventional Radiology 2001;0(05):-
A case of congenital pelvic arteriovenous malformation in a 41-years-old male treated by successful transarterial embolization was reported.This patient suffered from adult polycystic kidney disease and unknown reason for gross hematuria for four years.His left kidney was resected one year ago for suspected left nephrorrhagia but the hematuria remained.MRI examination of pelvis demonstrated AVM involving extensively the pelvic soft tissue,bladder and seminal vesicles.Bilateral internal iliac arterial angiography by DSA showed congenital pelvic arteriovenous malformations(CPAVM),the fringy anisotrophy vascular plexus supplied by many feeding arteries and drained into bilateral dilated and tortuous internal iliac venous branches.Super-selective catheterization and embolization for eight supplying blood branches,such as bilateral internal pudendal arterial branches,right obturator arterial branches,right inferior gluteal arterial branches,left superior vesical artery,left inferior vesical artery,spermatocyst artery and right lateral sacral artery etc,were carried out successfully with gelfoam sponge or PVA particulates in one time.His urine turned clear on the same day after arterial embolization,and no gross hematuria occurred during 6-months follow-up.The pelvic arterial angiography with embolization is extremely effective for the diagnostic and therapeutic measure of CPAVM.
4.Waste Gas Discharged from Hospital Central Vacuum Aspiration System and Its Sterilization by Nanometric Photocatalysis
Zhichen ZHANG ; Xiuluan ZHANG ; Ge WANG ; Fang ZHANG
Chinese Journal of Nosocomiology 2004;0(10):-
OBJECTIVE To discuss the sterilizing effect of waste gas discharged from hospital central vacuum aspiration system. METHODS According to the characters that direct discharging these waste gases from the central vacuum aspiration system would pollute surrounding environment and that there could not be choke in the venting part of vacuum pump of this system,the method of nanometric photocatalysis was adopted to sterilize the waste gases. RESULTS The average number of colony in the engine room was 2473.67?98.23CFU/m~3 before sterilization.After 1h and 2h of sterilizing,there were 88?17.6 CFU/m~3 and 58.76 ?12.34 CFU/m~3,respectively,with significant difference. CONCLUSIONS It is effective to use the method of nanometric photocatalysis sterilizing the waste gases from the hospital central vacuum aspiration system.The rate of the sterilization is 99.99%.
5.Application of Zero Defect Quality Concepts in Breathing Apparatus Management
Zhichen ZHANG ; Junying WANG ; Maorong KANG ; Wencheng XUE ; Tingting MI ; Yuanyuan ZHANG
Chinese Medical Equipment Journal 1989;0(01):-
Objective To investigate an effective method of breathing apparatus management. Methods According to the defect in process of breathing machine management, breathing apparatus management center was set up, related standards and procedures were established, the staff training was intensified and the management mode was expanded. Results The qualified rate of ventilator sterilization and breathing apparatus function were improved to 100% by applying zero defect quality management. Conclusion It is an effective method to ensure the safety and accuracy in breathing machine manage- ment with applying zero defect quality management.
6.An survey of brucellosis infection and exposure status of sheep farmers' family members in the western pastoral areas of Jilin Province
Fanyu LIU ; Chaoling GUAN ; Ye LI ; Zhichen YUAN ; Di WANG ; Qing ZHEN ; Yan YAO
Chinese Journal of Endemiology 2014;33(1):80-83
Objective To find out the current situation of brucellosis infection and exposure status of family members of sheep farmers in the western pastoral areas of Jilin Province,and to provide a reference for control of human brucellosis spreading among family members.Methods On November 2012,Qianguo County was randomly selected using a multi-stage sampling method,and two townships,Chaganhua and Wulantala,were randomly selected in the county; half of the villages were selected from each township; all family members of the sheep farmers in these villages were investigated about their demographic characteristics (sex,age,education),high-risk behavior and information about brucellosis infection by using a questionnaire survey.Based on the principle of informed consent,respondents venous blood samples were collected.Brucellosis was confirmed with serum agglutination test (SAT).The effects of gender,age,education and other demographic data,high-risk behavior and high-risk behavior protection on the prevalence of brucellosis were studied.Results Out of the 403 copies of qualified questionnaires collected,84 people were found infected with brucellosis,and the infection rate was 20.84% (84/403).Men infection [24.78% (57/230)] was higher than that of women [15.61% (27/173),x2 =5.038,P < 0.05].The rates of eight kinds of high-risk behaviors were:helping feeding 86.85% (350/403),cleaning sheepfold 80.40% (324/403),holding lamp 71.71% (289/403),delivering sheep 61.54% (248/403),vaccinating sheep 53.85% (217/403),apoblema 47.39% (191/403),milking 22.08% (89/403) and slaughtering sheep 14.89% (60/403).The highest risk behavior was vaccinating sheep[24.40%(53/217)],and the lowest was milking [16.90% (15/89)].The highest rate of basic protection was delivering a sheep [31.85% (79/248)],the next was apoblema[27.23% (52/191)],and the lowest was slaughtering sheep [8.33% (5/60)].There was no statistical significant difference between brucellosis infection and the eight kinds of high-risk behaviors as well as the basic protective behaviors.Conclusions The prevalence of brucellosis infection among sheep farmers' family members is higher than others.Brucellosis infection-related contact manner is ubiquitous and the level of basic protection is low.We should carry out targeted health education on sheep farming household members to improve their level of protection,so as to reduce the risk of brucellosis infection.
7.Management of Ventilator Tube System and Ventilator-associated Pneumonia
Zhichen ZHANG ; Xiuluan ZHANG ; Yuanyuan ZHANG ; Junying WANG ; Wencheng XUE ; Maorong KANG
Chinese Journal of Nosocomiology 1994;0(04):-
OBJECTIVE To analyze the relationship between the ventilator tube system and VAP.METHODS To investigate the way to use the ventilator tube system more reasonably.RESULTS To replace the ventilator tube every seven days could prevent the VAP effectively and decrease the mechanical ventilation patient′s mortality.CONCLUSIONS Decreasing the VAP incidence is a systematic and integrative work.To reinforce the management of the ventilator tube system is one of the effective methods in preventing VAP.
8.Suryey on awareness rate of Brucellosis prevention knowledge and behavior prevalence among primary and secondary school students in breeding livestock’s families in Western pastoral areas of Jilin province
Chaoling GUAN ; Zhichen YUAN ; Yan YAO ; Ping WANG ; Fanyu LIU ; Ruize WANG ; Di WANG ; Yong LI ; Qing ZHEN
Journal of Jilin University(Medicine Edition) 2014;(6):1303-1307
Objective To study the awareness of Brucellosis prevention knowledge and prevalence of risk behaviors among the primary and secondary school students from breeding livestock’s families in Western pastoral areas of Jilin province,and to provide evidence for the prevention and control of Brucellosis.Methods With application of multi-stage random sampling method,a questionnaire survey which including Brucellosis prevention knowledge and risk behaviors was conducted among 209 primary and secondary school students in west part of Jilin province in 2012.Results 105(50.97%)students had heard Brucellosis among 206 students,the older students knew more about Brucellosis than the younger(χ2 =28.80,P=0.00).The M(Q)of the score of the Brucellosis-related knowledge was 8(6.00,9.00),the total passing rate was 28.64%.72(68.61%)students learned Brucellosis from village doctors and acquaintances,only 11(10.51%)students learned it from school;the contact rates of eight kinds of high-risk behaviors were helping feeding 21.84%(62/206),holding lamb 16.50%(58/206),cleaning sheepfold 8.73%(26/206),vaccinating sheep 5.34%(17/206),milking 2.91%(6/206);cleaning apoblema 2.91%(6/206),slaughtering 2.42%(5/206)and delivering lamb 1.94%(4/206);there was no significant difference between the passing rate and the eight kinds of the basic protective behaviors except feeding (P>0.05).Conclusion The level of Brucellosis prevention knowledge is low in Western pastoral areas of Jilin province, and there was a high-risk of contact behavior with sheep and low basic protection rate. It indicates that the education about prevention and control of Brucellosis in the students from breeding livestork’s familes should be strengthened in order to prevent Brucellosis infection.
9.Research progress of correlation between ocular diseases and etiology of adolescent scoliosis
Jinbo ZHU ; Chenhang SUN ; Xiangyang WANG ; Chongan HUANG ; Haiming JIN ; Haofeng HONG ; Zhichen JIANG ; Hongyuan ZHANG ; Xiangxiang PAN
Chinese Journal of Orthopaedics 2021;41(5):322-329
The morbidity of scoliosis in adolescents in China is about 3%-5%, 80%-85% of the patients are adolescent idiopathic scoliosis (AIS), whose etiology is unknown. Scoliosis is a structural spine disease occurring during puberty or before skeletal maturation. Scoliosis has a greatly negative impacton not only the growth and development of adolescent spine, but also the mental health of adolescents. Ocular disease is a common clinical disease in which the eye ball and its accessory structures have structural abnormalitiesordys function. Ocular disease snotonly bring in convenience to patients's life, but also may induce diseases in other organs. Recent studies have shown that various ocular diseases may have a potential impact on scoliosis, and quite a fewof patients with certain ocular diseases have higher incidence rate of scoliosis. Therefore, in this article, the etiological relationship between eye diseases and scoliosis will be summarized, which provides guidance and direction for the etiological research of scoliosis and eye diseases. After sorting out, we found that the relationship between ophthalmic diseases and scoliosis mainly concentrated in the following four aspects: choroidal thickness and scoliosis, Goldenhar syndrome, gene level and strabismus. Among them, the genetic relationship is the most complex, about 40 kinds of gene or chromosome abnormalities have been found to cause ocular diseases and scoliosis; Goldenhar syndrome, also known as oculo-auriculo-vertebral spectrum, first revealed the relationship between ocular diseases and scoliosis, but the current statistical relationship is still very vague. There are few studies on choroidal thickness and strabismus at home and abroad, which are statistical studies, only revealing the relationship between choroidal thickness and scoliosis, and there are many defects in the study of choroidal thickness, which need further research.
10.Current status and research progress of microfluidic immunochips in medical detection
Zhichen ZOU ; Keguan SONG ; Qiushi SONG ; Fengnian ZHAO ; Shixin JIN ; Hongzhi WANG
Chinese Journal of Laboratory Medicine 2022;45(1):87-92
The traditional-immunological strategies for clinical laboratories often rely on large and expensive instruments and skilled operators, and the measurement time is also long. However, the sensitivity of these strategies is still unsatisfactory. It is urgent to research and develop the point-of-care testing (POCT) featured as a highly sensitive, accurate, and rapid/POCT diagnosis. The Microfluidic chips have multi-advantages that are suitable for the clinical POCT diagnosis: high sensitivity, throughput, and automation. Recently, the Microfluidic-immune chips developed based on the microfluidic technology combined with immune detection have considered not only hotspots in the related research but also benefit to the tumor marker detection, antigen and antibody detection of infectious diseases, autoantibody detection, hormone detection, and other fields. However, there are still many challenges to be overcome during the application of chips, such as more effective microfluidic manipulation, more sensitive collection, and analysis of reaction signals.