In order to investigate the relationship between sex hormone receptor or glucocorticoid receptor(GR) and hepatocellular carcinoma(HCC), the contents of androgen receptor(AR) and estrogen receptor(ER) in peripheral blood lymphocytes, and GR in peripheral blood leukocytes from 13 patients with HCC and 23 healthy persons were measured by the method of radio-ligand receptor binding. The results showed that the contents of ER and AR in control group were 616?06 and 687?09 site/cell respectively: and those in HCC group were 968?20 and 2903?60 site/cell; while the content of GR in control group was 5360?1684 site/cell, and those in HCC with and without cirrhosis group were 3112?130 and 4536?201 site/cell respectively. The level of AR indicated that HCC is well correlated with AR and HCC may be an androgen-dependent tumor. The GR level is negatively correlated with the degree of liver cirrhosis. The result demonstrated that the GR contents reflect the degree of liver cirrhosis.

The talus fracture is a rare kind of fracture in clinical work in the department of orthopedics due to the special structure of the talus.It is usually caused by high altitude falling accidents and serious violence,etc.Associated with the economic development,the talus fracture cases are found with increasing trend caused by serious traffic and building accidents.In this review,we will summarize the main progresses contributed to knowledge of anatomy and blood supply,damage mechanism and classification,and especially the diagnosis and treatment of talus fracture.

Objective To investigate the diagnostic value of calcification and cystic lesion of CT findings in differentiating pancreatic head ductal carcinoma (PHDA)from mass-forming chronic pancreatitis (MFCP)of the pancreatic head.Methods The clinic data and CT findings of 30 cases with PHDA and 24 cases with MFCP of the pancreatic head,which were confirmed by surgery and pathology were analyzed retrospectively.The images were reviewed independently by two expert radiologists with a double-blind method.An independent sample t test and chi-square test were used to compare the data of imaging findings between two groups.Results ① Calcification was found in 14 cases (58.33%)with MFCP and in 3 cases (10%)with PHDA (P＜0.001).The percentage of patchy,punctate and mixed calcification were 28.57% (n=4),14.29% (n=2)and 57.14% (n=8)in MFCP,0% (n=0),66.67% (n=2)and 33.33% (n=1) in PHDA,respectively.② Necrotic cyst was founded in 7 cases (29.17%)with MFCP and 18 cases (60%)with PHDA(P＜0.05). Pseudocysts were demonstrated in 14 cases (58.33%)with MFCP and in 3 cases (10%)with PHDA (P＜0.001).Honeycombed change with tension within or around the lesion were demonstrated only in patients with MFCP.In addition,normal tissue of the pancreas was found within the lesion in 11 cases (45.83%)of MFCP and none in PHDA,which showed significant difference between two groups.Conclusion Mixed calcification and honeycomb with tension of CT findings are of significant value in differentiating PHDA from MFCP of the pancreatic head.

Objective To evaluate CT vs.MRI in the intrapancreatic and relevant extrapancreatic findings of acute pancreatitis (AP).Methods The clinical data and image findings of 52 AP cases from Jan 2015 to Jun 2017 were analyzed retrospectively.Results CT is comparable to MRI in the diagnostic value of pancreatic enlargement and pancreatic necrosis (all P ＞ 0.05).Compared to CT,MRIwas superior in detecting the peripancreatic exudes,thickening of renal fascia,pleural effusion and abdominal wall edema (all P ＜ 0.01).In favor of MRI,there was significant difference in detection of gallbladder stones and choledocholithiasis,and hepatic swelling,hepatic fatty infiltration.Conclusions Both CT and MRI are significantly helpful to the early precise diagnosis of AP,while MRIis superior in showing etiology,pancreatic hemorrhage and necrosis,extrapancreatic lesions.

OBJECTIVE: To investigate the pattern and value of the expression of T-bet in nasopharyngeal-associated lymphatic tissue (NALT) of patients with or without allergic rhinitis (AR). METHOD: T-bet and CD4/T-bet expression in adenoids, tonsils and nasal mucosa was respectively detected with single stain and double stain of immunohistochemistry. RESULT: The positive ratio of T-bet expression in tonsils, adenoids and nasal mucosa between AR group and the control group had statistically different (P < 0.05). There was statistical difference of T-bet expression in tonsils from AR group in three different age groups (P < 0.05). The difference was that T-bet expression in adults group was significantly lower than that in children group and adolescent group. There was no difference of T-bet expression among different age groups in non-AR group. There were some positive expression of CD4 and T-bet in tonsils, adenoids and nasal mucosa from two groups and most positive expression of T-bet on CD4 positive cell. CONCLUSION T-bet expression was down-regulated in NALT of patients with AR. T-bet expression of NALT is associated with allergic mucosal inflammation and functional status of NALT, as well as the weak Th1 response at the level of transfer factor in local mucosa of respiratory tract in AR patients.
Adolescent ; Adult ; Child ; Humans ; Lymphoid Tissue ; metabolism ; Palatine Tonsil ; metabolism ; Rhinitis, Allergic, Perennial ; metabolism ; T-Box Domain Proteins ; metabolism ; Young Adult