1.MONITORING OF BRAIN ACTIVITIES IN ANESTHETIZED AND CRITICAL PATIENTS
Medical Journal of Chinese People's Liberation Army 1983;0(02):-
This paper reported the characteristics and regular patterns of the changes in computerized quantitative electrocncephalogram(EEGcq) and frontal electromyogram(EMGf) in 331 patients under the effect of various inhaled and intravenous anesthetics, and the changes in the EEGcq and EMGf during cerebral ischemia caused by serious hypotention or arrhythmia, feeble heartbeat, cardiac electromechanical dissociation and hypoperfusion during extracorporeal circulation. It was found that the amplitude of EEGcq decreased with a"suddenly coming and departing appearance"when the anesthesia with isofl-uorane was excessively deepened or the course of becoming light, that the EEGcq amplitude displayed on the screen showed frequent sharp uprisings when the anesthesia with enfluorane was excessively deepened, that the response of EMGf to various hurtful stimuli presented spikes when anesthesia was inadequate, and that the EMGf showed plateau tracings when the anesthesia was very light.
2.Characteristics of hysteromyoma MRI images
Haiyan WEN ; Wenzhi CHEN ; Zhibiao WANG
Journal of Third Military Medical University 2002;0(12):-
Objective To study the common imaging characters of the human tissues such as tumors in MRI based on hysteromyoma in hope of getting the results that the same tissue has the same MR characters and identifying the common,comparatively steady MR figs sectional area which can provide related references for the computer-based automatic recognition orgnization and basis for the question such as whether the same MR figs has the same hyperacoustic impedance characters.Methods We analysed all the images with hysteromyoma on MRI T2 and got the rules on MR figs change with the application of the MRI image analysing software which specially designed by Microsoft Visual C++ 6.0 for the research.Results(1)No significant difference was found in MR figs sectional area in the different periods of the same patient under the same MRI test condition.(2)No significant difference was found in MR figs sectional area in different patients under the same MRI test condition.(3)Significant difference was found in MR figs sectional area after the patient received the HIFU treatment under the same MRI test condition.Conclusion(1)Human tissues have some common MRI imaging characters in the same MRI test equipment under the same MRI test condition.(2)Imaging characters of the human body tissues in MRI can be altered after HIFU treatment.
3.Automatic drawing on target therapy area in HIFU treatment based on MRI and CT imagings
Haiyan WEN ; Wenzhi CHEN ; Zhibiao WANG
Journal of Third Military Medical University 2003;0(21):-
Objective To study automatic drawing on target therapy area based on MRI and CT imagings in order to get the precision less than 1 mm in HIFU treatment.Methods Based on MRI and CT imagings,automatic image was recognized and the frame was extracted by image processing and image segmentation,etc..Results The system of software we are studying can be effectively used to recognize medical automatic images and get target therapy areas' image drawings.Conclusion This system of software will be used in medical precise treatment systems,such as HIFU 3D Treatment Regional Planning System.
4.Cost for several immuno-diagnostic systems in trichinosis developed in recent ten years
Yan WEN ; Yueqing ZHANG ; Zhaoyong WU ; Minjun HUANG ; Zhibiao XU
Chinese Medical Journal 1998;111(7):0-0
Objective To evaluate the cost-effectiveness of various immuno-diagnostic systems for trichinosis and to find out the best testing system with low cost and high effectiveness.Methods The basic methods for the research are to difine and classify the direct and indirect cost for each testing system, and to identify a cost-effective testing system which would be practical and workable in case finding and/or mass survey. The data collected were analysed with parameters which are as follows: (1) the parameter of cost effectiveness expressed by cost/one sample in a given test that is unit cost. (2) the parameters of cost effectiveness: (a) for finding patients: cost/positive rate; (b) for examination carried out in normal individuals: cost/(100%-positive rate); (c) for the result of cross reaction: cost/(100%-cross reaction rate).Results Among the costs for detecting antibodies,the total costs vary from 98.06 yuan to 193.15 yuan. F-ELISA is the cheapest test. The unit cost for the five studied testing systems is ranging from 3.98 yuan to 4.22 yuan. According to the cost, the recommended order would be: F-ELISA, SPA-ELISA, ELISA, Western blot and IIP.Using the value of cost/effectiveness in analysis of the cost and comparing the results of detecting the positive cases ,the normal persons and cross reaction. The final results show that the methods for detecting antibodies are not only cheap but also practical and the preference for selection would be F-ELISA, ELISA and SPA-ELISA. The best method for detecting antigens is F-PcAb.Conclusions When these methods are used in practice, we suggest that F-ELISA should be the best method for choice in screening, when the result is positive, F-PcAb may be used for confirmation and can obtain a correct diagnosis.
5.Effects of therapeutic dose on temperature rise induced by high intensity focused ultrasound in tissue.
Faqi LI ; Qiang ZHANG ; Yonghong DU ; Guihua XU ; Shuang WEN ; Jin BAI ; Feng WU ; Zhilong WANG ; Zhibiao WANG ; Ruo FENG
Journal of Biomedical Engineering 2003;20(3):466-471
Based on the well-known Pennes' bioheat equation, we analyzed theoretically the temperature rise in tissue during high intensity focused ultrasound(HIFU) irradiation, and measured the focal temperature rise induced by HIFU in the treatment of freshly excised cow liver with different acoustic intensity and exposure time. The results showed that a threshold exposure time always existed under a certain acoustic intensity. Temperature rise was slow when exposure time exceeded the threshold exposure time. The greater the acoustic intensity was, the earlier the threshold time appeared. The focal temperature rise and the relative cumulative thermal dose (RCTD) increased with the increase of acoustic intensity and exposure time. For a certain therapeutic dose, the effects of acoustic intensity on focal temperature rise were more distinct than the effects of exposure time on focal temperature rise. Therefore, the optimal HIFU therapeutic dose should meet the need, i.e. moderate acoustic intensity, and the exposure time be the threshold exposure time under this acoustic intensity.
Animals
;
Body Temperature
;
Cattle
;
Hyperthermia, Induced
;
methods
;
In Vitro Techniques
;
Liver
;
diagnostic imaging
;
physiology
;
Models, Theoretical
;
Time Factors
;
Ultrasonic Therapy
;
methods
;
Ultrasonography
6.Emergency treatment of aortic dissection and clinical pathway discussion
Guangzhong XIONG ; Jinlong ZHAO ; Xiangping CHAI ; Zaimei PENG ; Dongshan ZHANG ; Changlong BI ; Xiao FAN ; Shuangfa QIU ; Zhibiao HE ; Hongliang ZHANG ; Yao RONG ; Tie WEN ; Xudong XIANG ; Chang SHU ; Xinming ZHOU
Chinese Journal of Emergency Medicine 2011;20(6):646-649
Objective To investigate the clinical features of aortic dissection (AD) and emergency treatments. Methods Data from 784 patients with aortic dissection were collected in the Department of Emergency from January 2000 through December 2009. A retrospective analysis was carried out to determine the survival rate, mortality rate and treatment efficiency. Results Pain was the most common onset symptom (77.7% , 609/784). The majority of patients (86.5%) had essential hypertension (678/784). All the patients with preoperative diagnosis of aortic dissection underwent emergency medical intervention by internists resulting in 81.5% survival rate (639/784) and 18.5% mortality rate (145/784). There were 157 patients without improvement (20.0% ) and the total efficiency rate was (83. 1% ). The efficiency rate of conventional treatment was 76.4% , while the efficiency rate of triple four-procedure treatment was 89. 8% (P<0.05). Of them, 139 patients (17. 7% ) died in the hospital. Among them,. 26 patients died within 24 hours (18.4% ) and 47 cases died within 48 hours (33. 8% ) and 66 patients died within 72 hours (47.2% ). There were 92 patients who refused treatments after diagnosis, and among them, 81 patients died within 72 hours (88.04% ). The difference in mortality rate between two groups was significant (P<0.05). Conclusions The diagnosis of aortic dissection depends on detailed history, physical examination and CT or MRI imaging. Analgesia, sedation and control of blood pressure are essential for emergency treatments. Early diagnosis and effective emergency treatments are the critical strategy for the early surgical intervention and time window for further treatment to improve the survival rate of AD.