1.Comparison of Contrast-enhanced Ultrasound, Contrast-enhanced CT and Contrast-enhanced MRI in the Diagnosis of Renal Space-occupying Lesions
Zhi ZHANG ; Zizhuo ZHAO ; Jingliang RUAN ; Jing TIAN ; Baoming LUO
Chinese Journal of Medical Imaging 2014;(10):764-767
Purpose To compare the value of contrast-enhanced ultrasound (CEUS), contrast-enhanced CT (CECT) and contrast-enhanced MRI (CEMRI) in the diagnosis of renal space-occupying lesions. Materials and Methods Seventy-eight patients whose 80 kidney space-occupying lesions were conifrmed by traditional ultrasound underwent CEUS examination. Among those patients, 39 patients also underwent CECT, 28 had CEMRI, and 5 had CECT and CEMRI examination together. Taken pathologic findings as gold standard, the value of conventional ultrasound, CEUS, CECT and CEMRI was compared in the diagnosis of renal space-occupying lesions. Results Among 80 renal masses, 57 lesions were malignant and the rest 23 lesions were benign. The diagnostic sensitivity, speciifcity, positive predictive value and negative predictive value were 93.0%, 69.6%, 88.3%, 80.0%for CEUS;those for CECT were 96.4%, 72.7%, 90.0%, 88.9%respectively;and for CEMRI were 86.4%, 66.7%, 90.5%, 57.1%respectively;and the diagnostic value among the three means showed no difference (P>0.05). Conclusion CEUS, CECT and CEMRI are all effective in the diagnosis of renal space-occupying lesions, We may select suitable examination means for patients according to their features. A combination of these techniques provides more information for the diagnosis of renal space-occupying lesions.
2.Clinical study on skin needling plus heat-sensitive moxibustion for chronic facial paralysis
Yanfeng XIE ; Yongdui RUAN ; Wenzhu WEI ; Xiaojun NING ; Zhi ZHENG
Journal of Acupuncture and Tuina Science 2015;(3):185-188
Objective:To observe the clinical efficacy of skin needling plus heat-sensitive moxibustion in treating chronic facial paralysis. Methods:Sixty patients with chronic facial paralysis were divided into an observation group and an acupuncture group by using the random number table, 30 in each group. Patients in the observation group were given skin needling plus heat-sensitive moxibustion; while patients in the acupuncture group were given conventional acupuncture. Results:Three treatment courses later, the total effective rate was 93.3% in the observation group versus 86.7% in the control group, and the difference was statistically significant (P<0.05). Conclusion:Skin needling plus heat-sensitive moxibustion can produce a more significant efficacy than conventional acupuncture in treating chronic facial paralysis.
3.Research management of the hospital build a new way
Mei YANG ; Peng RUAN ; Weihua LIU ; Yun PENG ; Zhi WANG
Chinese Journal of Medical Science Research Management 2015;28(1):20-22
Hospital Research Branch to provide diversity of services should rely on a combination of different professionals composite research management department.This paper analyzes the current status of the hospital research management staff proposed the formation of complex multifunctional research subjects and their personnel training programs,and the staff have made short-term and long-term co-ordination of running countermeasures,as well as multi functional management functions method.
4.Reasearch on mechanism of neurotrophins in discogenic low back pain.
Zhi-Wei JIA ; Bao-Ku ZHANG ; Di-Ke RUAN
China Journal of Orthopaedics and Traumatology 2012;25(8):698-700
Discogenic low back pain is the common type of chronic low back pain. However,its mechanism has not been completely clarified. Considerable evidence shows that neurotrophins play an important role in discogenic low back pain. The paper summarizes the mechanism of neurotrophins on discogenic low back pain according to the pain transfer pathway of neurotrophins in intervertebral disc, dorsal horn ganglia and spinal trigeminal nucleus. Changing the pain transmission by regulating neurotrophins and its receptor will provide a new way for the treatment of discogenic low back pain.
Humans
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Intervertebral Disc
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metabolism
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pathology
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Low Back Pain
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metabolism
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pathology
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Nerve Growth Factors
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metabolism
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Posterior Horn Cells
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pathology
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Trigeminal Nucleus, Spinal
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pathology
5.Surgical treatment of primary pulmonary low-grade malignant carcinoma.
Ming HAN ; Junzhong RUAN ; Xiuyi ZHI
Chinese Journal of Lung Cancer 2002;5(4):287-289
BACKGROUNDTo arrive at a rational diagnosis and effective surgical treatment of primary pulmonary low-grade malignant carcinoma.
METHODSEighty-nine patients with primary pulmonary low-grade malignant carcinoma received surgical treatment from 1956 to 2000.
RESULTSOut of the 89 patients, 54 were bronchial carcinoid, 18 were mucoepidermoid cancer, and 17 were adenoid cystic carcinoma. The operative procedures included resection of tracheal carcinoma in 3, lobectomy in 49, sleeve lobectomy in 14, total pneumonectomy in 14, and wedge pneumonectomy in 6. All patients were complaint free. The 5-year survival rates of bronchial carcinoid and adenoid cystic carcinoma were 91.3% and 70.6% respectively, and no patients with bronchial mucoepidermoid cancer died until now.
CONCLUSIONSBronchial carcinoid, adenoid cystic carcinoma and mucoepidermoid cancer are a series of primary pulmonary carcinoma of low malignant potential, whose predilection sites are main or lobe bronchi, and clinical symptoms are repeated infection of the lung or intermittent hemoptysis. The diagnosis depends on radiography or CT scan of chest and bronchofiberscopy. The operation is most important, and whose procedure is lobectomy or sleeve lobectomy mainly.
6.Analysis of the county-level evaluation results after reaching the goal of eliminating iodine deficiency disorders in Longyan city, Fujian province in 2009
Jian-an, CHEN ; Yong-gui, LAN ; Hui-qin, CHEN ; Xue-ling, RUAN ; Zhi-peng, ZHOU
Chinese Journal of Endemiology 2011;30(2):165-168
Objective To understand the current situation of iodine deficient disorder(IDD) 10 years after achieving the stage goal of eliminating IDD in Longyan city and to evaluate the effect of prevention and treatment measures, and to provide the basis for the development of control strategies. Methods There were 7 counties in the city, and each county(city, district) was as a unit to carry out the inspection for organization and leadership,iodine salt management, monitoring and control, health education (referred to as the four management indicators)according to "The County-Level Assessment and Evaluation Implementation Detailed Rules of Realizing the Goal to Eliminate IDD in Fujian Province". According to the east, west, south, north and middle positions in each county,a village and a primary school were selected. Forty 8 to 10 year-old students in each school were randomly selected to check thyroid and among them 20 students were collected urine samples to determine urinary iodine. Nine townships were selected in the 7 counties of the city and among which 4 administrative villages were selected in each township. Eight edible salt samples from each household in each administrative village were collected to test salt iodine. Goiter was examined by palpation, the level of urinary iodine was examined by arsenic and cerium spectrophotometry, salt iodine was detected by direct titration. Results The average score of the four management indicators was 94.1 in Longyan city. The adjusted goiter rate of children aged 8 - 10 years old was 1.9%. The median of urinary iodine was 278.6 μg/L, among which less than 100 μg/L accounted for 4.57%(32/700), 100 -< 200 μg/L accounted for 24.00%(168/700), 200 - < 300 μg/L accounted for 25.29%(177/700), and higher than 300 μg/L accounted for 46.14%(323/700). The using rate of qualified iodized salt was 98.86%. The coverage rate of iodized salt was 99.50%, the qualified rate of iodized salt was 99.35%, and the rate of non-iodized salt was 0.50%. All the indicators had reached the national standard to eliminate IDD. Conclusions After achieving the stage goal of eliminating IDD, the disease is stable and the effect of control measures are significantly. But the iodine provided has a trend of more than suitable. Therefore, it is reasonable to reduce the current salt iodine content.
7.Malignant blood disease great amount of application curative effect IL-2 observes after the chemotherapy
Zhi GUO ; Xiaodong LIU ; Xinjian RUAN ; Jinxin LOU ; Xuepeng HE ; Xiaohua TAN
Journal of Leukemia & Lymphoma 2008;17(2):123-124
Objective The clinical curative effect observed the empress of the chemotherapy of malignant blood disease big mount of an application IL-2. Methods The review analyzes 65 malignant chemotherapy be over of the blood patient's (treatment set) juniorses to go a big quantity IL-2 treatments,(matched control) choose random of 98 sufferer's chemotherapy be overs don't carry on any immunity treatment behind. Results With visit be over the covariance relapse a rate: the treatment set is 28 %, the matched control is 42 %; Medium exist a period: the treatment set is 44(0~80) months, the matched control is 21(0~80) months. Conclusion For the leukemia, lymphoid lump etc. malignant blood patient the chemotherapy gives after ending big quantity IL-2 immunity treatment is a kind of to cure a method effectively, after maying reduce a sufferer a chemotherapy of relapse a rate, also hope extension existence a period.
8.The clinical observation of oxaliplatin combined with capecitabin for patients with advanced colorectal cancer
Xin-Jian RUAN ; Jian-Fei WANG ; Zhi GUO ; Zhao-Liang CHEN ; Xia ZHANG ;
Cancer Research and Clinic 2000;0(06):-
Objective To observe the therapeutic effect and toxicity reaction of Oxaliplatin com- bined with XeLoda in the treatment of 42 patients with advanced colorectal cancer.Methods All the pa- tients were treated with Oxaliplatin(130 mg/m~2,ivgtt for 2 h,d1)combined with XeLoda(2000 mg?m~(-2)?d~(-1), po,bid,d1 to d14).The regime was repeated every 21 days for at least 3 consecutive cycles.Results The to- tal response rate was 40.5%(17/42)in which 2 got CR and 15 PR.24 patients got Kamofsky score increased. The major toxic effects were alopecia,peripheral neuritis,gastrointestinal tract reactions and myelosuppression. Conclusion Oxaliplatin combined with XeLoda regimen is effective in the treatment of advanced colorectal cancer,and its toxicity is tolerable.It is worth studying in the future.
9.Extension of service life for CT tubes
Yi ZHU ; Shu-Bo YANG ; Xin-Yun RUAN ; Zhi-Rong XU ;
Chinese Medical Equipment Journal 2003;0(10):-
X-Ray tube is the core part of CT machines and its service life is closely tied to its quality,installation & adjustments and the status of the equipment itself.Besides,whether the operaters use the equipment correctly or not also influence the life of X-ray tubes.The author summarizes some methods for extending the life of CT tubes according to the experiences of installation,adjustment and using of the CT tubes for many years.
10.Efficacy comparison of tissue selecting therapy stapler and procedure for prolapse and hemorrhoids in the treatment of severe hemorrhoids.
Ning RUAN ; Zhi-hua CHEN ; Xia-bing LIN
Chinese Journal of Gastrointestinal Surgery 2013;16(7):645-647
OBJECTIVETo compare the efficacy and complication of tissue selecting therapy stapler (TST) and procedure for prolapse and hemorrhoids (PPH) in the treatment of severe hemorrhoids.
METHODSClinical data of 542 cases of severe hemorrhoids undergoing TST (258 cases) or PPH (284 cases) in The First Affiliated Hospital of Fujian Medical University from November 2010 to January 2012 were analyzed retrospectively. Operative parameters, efficacy and complication 3 months after operation were assessed and compared.
RESULTSNo significant difference in cure rate between TST and PPH (96.5% vs. 95.4%) was found, while the operation time and hospital stay after operation in TST group were significantly shorter urgency [(20.6±4.7) vs. (26.4±6.3) min, (2.9±0.5) vs. (3.5±0.7) d, both P<0.05]. Incidences of postoperative pain, bleeding, anal urgency and urinary retention in TST group were significantly lower than those in PPH group (all P<0.01). No anal stenosis was observed in TST group, and 5 cases developed anal stenosis in PPH group (P<0.05). Hemorrhoid recurrence did not differ significantly between the two groups.
CONCLUSIONSThe efficacy of TST and PPH is comparable for severe hemorrhoids patients, while TST is associated with faster postoperative recovery and less complications.
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Female ; Follow-Up Studies ; Hemorrhoids ; surgery ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Surgical Stapling ; methods ; Treatment Outcome ; Young Adult