Objective To discuss the clinical effect of entecavir in treatment of hepatitis B-related nephritis. Methods 28 patients with hepatitis B-related nephritis diagnosed in our hospital through needling biopsy of kidney from 2009 to 2012 were selected in this study. All patients were given oral entecavir, besides conprehensive treatments,including potassium aspartate and diammonium glycyrrhizinate. The treatment course was three months. We observed and analyzed patients' serum glutamic pyruvic transaminase, serum albumin and urine protein within 24 hours after two treatment courses.Results After one treatment course, the overall effective rate was 82.14%. Two courses later, the overall effective rate was 96.43%. Patients' serum glutamic pyruvic transaminase, serum albumin and urine protein within 24 hours after two treatment courses had significant differences with those before treatment's,the difference had statistical significance ( <0.05),but serum creatinine had no significant change after treatment. Conclusion Entecavir has significant curative effect on hepatitis B-related nephritis.

Fracture Fixation ; methods ; trends ; Fractures, Bone ; surgery ; Humans ; Pelvic Bones ; injuries ; surgery

China ; Humans ; Occupational Diseases ; prevention & control ; Occupational Health ; legislation & jurisprudence ; Occupational Health Services ; organization & administration ; standards

Objective To explore the feasibility of conservative treatment in patients with ectopic pregnancy.Methods The clinical data of 38 cases of ectopic pregnancy treated with conservative treatment were retrospectively analyzed.Results All the 38 patients with ectopic pregnancies were treated with MTX single dosage.There were 7 patients who failed in the conservative treatment and the rest of which were successfully cured.Conclusion For those early diagnosis and strictly selected ectopic pregnancy patients .conservative drug treatment is safe and effective.

Objective To investigate the clinical effect of implantable collamer lens ( ICL) in the treatment of super high myopia. Methods 20 patients with high myopia were given ICL,and changes in patients with visual acuity,intraocular pressure and corneal endothe-lial cells,and surgery-related complications and outcome were observed. Results Before surgery,the visual acuity of patients was (0. 10±0. 05),and postoperative (0. 60±0. 20),the difference was statistical significance(P<0. 05);the intraocular pressure and corneal endothe-lial cells of patients did not change significantly after surgery,with less postoperative complications. Conclusion The ICL has a very signifi-cant effect in the treatment of super high myopia,which can help to improve the patient's quality of life,and it is worthy of wide promotion and application.

The zymograms of lactate dehydrogenase (LDH) and esterase (EST) isoenzymes in different physiologic state from two species of Anopheles mosquitoes were studied with polyacrylamide gel electro -phoresis. Some zymogram variation of LDH from single female mosquito was found after engorged blood meals for 48 h, that consisted of two main bands whose relative mobility (Rm) was different. The isozymograms of EST showed some similar characteristics of sibling which divided into three groups ESTⅠ, ESTⅡand ESTⅢ, respectively. The two species of mosquitoes could be differentiated from each other by the particular band in EST Ⅱ group of An. anthropophagus.

A simple and reliable procedure for the isolation of pure DNA from human fetal liver is described.A high pure and natural DNA with an average molecular weight of 4 ?106 can be easily obtained after the sample is treated with SDS and trypsin and fractionated by a sepharose 4B column.The product meets the requirement for general research work of molecular biology.

This paper is to report the results of the clinical application of the Shexiang hemostasis-removing plaster. 265 cases of dermatohemostasis including chilblain, erythema multiforme, erythema nodosum, and so on were treated locally with Shexiang hemostasis-removing plaster. 20 cases of dermatohemostasis were treated with Shexiang analgesic plaster and served as control.It was found the rates of marked improvement and improvement after the application of Shexiang hemostasis-removing plaster were 85.61% and 96.60%, while those after Shxiang analgesic plaster treatment were 65% and 90% respectively. It is bovious that Shexiang hemostasis-removing plaster is more effective in treating dermatohemostasis than Shexiang analgesic plaster. The difference between the 2 is statistically significant(P

Aim This study aimed to observe effects of tyroserleutide(tyrosyl-seryl-leucine,YSL) on the survival time of mice transplanted with the ascitic fluid-type hepatocarcinoma H_(22),as well as the T lymphocyte transformation and killing activity of NK cell impacted by YSL on mice bearing H_(22) tumor.Methods The model of ascetic fluid-type hepatocarcinoma H_(22) was established and the survival time of mice bearing H_(22) tumor treated by YSL was observed.MTT was used to observe the effect of lymphocyte transformation and killing activity of NK cells activated by YSL in vitro.Results YSL could significantly prolong the survival time of mice bearing ascetic fluid-type hepatocarcinoma H_(22).At doses of 5 and 50 ?g?kg~(1),YSL could advance the T lymphocyte transformation.At doses of 0.5,5 and 50 ?g?kg~(-1),YSL could enhance the killing activity of NK cells on mice bearing H_(22) tumor.Conclusion YSL can significantly prolong the survival time of mice bearing fluid-type hepatocarcinoma H_(22) and promote the effect of T lymphocyte transformation and NK cell killing activity.

Acute kidney injury(AKI) can lead to remote organ damage.The specific mechanism by which the AKI results in distant organ damage is yet to be determined.In animal models,it has become increasingly clear that AKI is not an isolated event but results in remote organ dysfunction involving the heart,lungs,liver,and brain.This review summarizes the effects of AKI on remote organs.